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The map label for this gene is pgsA2 [H]

Identifier: 50842490

GI number: 50842490

Start: 1092046

End: 1092660

Strand: Direct

Name: pgsA2 [H]

Synonym: PPA1007

Alternate gene names: 50842490

Gene position: 1092046-1092660 (Clockwise)

Preceding gene: 50842489

Following gene: 50842491

Centisome position: 42.65

GC content: 55.61

Gene sequence:

>615_bases
ATGGCCACGAAGAAGGACCGTCCCAGCAGCATCAACGTTCCCAATGCGCTGACCCTGCTGAGGGTCGTTGCGGTTCCCAT
CTTCGGATGGATGCTATTAGCCCATGCTCATGAAGGTGGCTGGCGGACGACAACGACGATCGTTTTCATGGTGGCGATCC
TCACCGACTTCGTCGATGGCAAGGTTGCTCGTAAATACAACCTCGTCACCAACTTCGGCAAGATCGGTGATTCGATTGCT
GACAAAGCACTGACCGGCATGGCCTTTATCGGCCTCTCGATTATCGGCGAACTCCCGTGGTGGATGACGATTATCATCCT
GTTGCGTGAATGGGGCATCACCGTCATGCGAATGAAGATGCTCAAGTACAAGGTGATGGCGGCTAACAAGGGCGGCAAAC
TGAAAACGGCCATGCAGTCGCTGGCGATTACGCTGTTCTGCCTGGGCTTGTGGCGCATGCCTACTTTTGTCTACGTCATC
GCCTGGGCGGTCATGATCATTGCCTTCGTCCTCACAGTGATTACCGGCCTGGTGTACATCCGCGACGCCATTCTCATTCG
TAACCGCGCAAAGATGACCGAGTCCAGGCCGGCCCGGAAGCGCACGCTCAAATGA

Upstream 100 bases:

>100_bases
ACTAGCCGTCGATCTCAGCGCGCTGCCAAAAAGTGATCAATCCGAGTCGCTTCCAGGGCGGTGAGTCGCATGAGGCATCG
TCACGCGACATACTGAGCCT

Downstream 100 bases:

>100_bases
CTGGCGATGAAGGAGCCCGTCGGCTCATTGCGGTGCTGTCTGAGCATGGACTGACGGCCGCAACCTGCGAATCTCTAACG
GCTGGTCTTGTCGCCGCGAC

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MATKKDRPSSINVPNALTLLRVVAVPIFGWMLLAHAHEGGWRTTTTIVFMVAILTDFVDGKVARKYNLVTNFGKIGDSIA
DKALTGMAFIGLSIIGELPWWMTIIILLREWGITVMRMKMLKYKVMAANKGGKLKTAMQSLAITLFCLGLWRMPTFVYVI
AWAVMIIAFVLTVITGLVYIRDAILIRNRAKMTESRPARKRTLK

Sequences:

>Translated_204_residues
MATKKDRPSSINVPNALTLLRVVAVPIFGWMLLAHAHEGGWRTTTTIVFMVAILTDFVDGKVARKYNLVTNFGKIGDSIA
DKALTGMAFIGLSIIGELPWWMTIIILLREWGITVMRMKMLKYKVMAANKGGKLKTAMQSLAITLFCLGLWRMPTFVYVI
AWAVMIIAFVLTVITGLVYIRDAILIRNRAKMTESRPARKRTLK
>Mature_203_residues
ATKKDRPSSINVPNALTLLRVVAVPIFGWMLLAHAHEGGWRTTTTIVFMVAILTDFVDGKVARKYNLVTNFGKIGDSIAD
KALTGMAFIGLSIIGELPWWMTIIILLREWGITVMRMKMLKYKVMAANKGGKLKTAMQSLAITLFCLGLWRMPTFVYVIA
WAVMIIAFVLTVITGLVYIRDAILIRNRAKMTESRPARKRTLK

Specific function: This Protein Catalyzes The Committed Step To The Synthesis Of The Acidic Phospholipids. [C]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=186, Percent_Identity=32.258064516129, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22904; Mature: 22773

Theoretical pI: Translated: 11.31; Mature: 11.31

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKKDRPSSINVPNALTLLRVVAVPIFGWMLLAHAHEGGWRTTTTIVFMVAILTDFVDG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
KVARKYNLVTNFGKIGDSIADKALTGMAFIGLSIIGELPWWMTIIILLREWGITVMRMKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LKYKVMAANKGGKLKTAMQSLAITLFCLGLWRMPTFVYVIAWAVMIIAFVLTVITGLVYI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDAILIRNRAKMTESRPARKRTLK
HHHHHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure 
ATKKDRPSSINVPNALTLLRVVAVPIFGWMLLAHAHEGGWRTTTTIVFMVAILTDFVDG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
KVARKYNLVTNFGKIGDSIADKALTGMAFIGLSIIGELPWWMTIIILLREWGITVMRMKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LKYKVMAANKGGKLKTAMQSLAITLFCLGLWRMPTFVYVIAWAVMIIAFVLTVITGLVYI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDAILIRNRAKMTESRPARKRTLK
HHHHHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036; 10889206 [H]