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The map label for this gene is fabH1 [H]

Identifier: 50842467

GI number: 50842467

Start: 1065912

End: 1066910

Strand: Reverse

Name: fabH1 [H]

Synonym: PPA0983

Alternate gene names: 50842467

Gene position: 1066910-1065912 (Counterclockwise)

Preceding gene: 50842468

Following gene: 50842466

Centisome position: 41.67

GC content: 62.16

Gene sequence:

>999_bases
ATGACGGCCATCAAGACCCGTCCCGTCCACGGCTACTCGAAATTCCTGTCCACCGGATCAGCTCGCGGATCGCGAGTAGT
CACCAACAAGGAGATGTGCACGCTCATCGACTCCACCCCAGAGTGGATCGAACAGCGTACCGGCATTACCGAGCGGCGCT
GGGCCACCAACTCTGAGACTGTGGCGTCCATGGGCACCACAGCCGCGCGTACCGCCCTAGAGCGATCCGGGCTGGAGGCA
TCCCAGATCGATGCCATCATCGTGGCGACCGTGTCACATCATCGTCCTTCCCCCAGCTTGGCGGCTTACATCGCCCGGGA
GCTCGGCTTGGGTGACGCTGCTGCGTTTGACCTCAACGGCGCATGTGCTGGGTTTTGCTACTCAACCGCTCTGGCTGACT
CAATGATCCGCACCGGATCGGCGAATTACGTCCTCGTTATCGGCGTCGAGAAGCTCTCGGAAATGACGAATCTTGACGAC
CGCTCCACCGCCTTCCTCTTCTCTGACGGGGCTGGTGCCGCAATCATCGGTGCCAGCGATGAGCCGGGGATCGGCCCGGT
GGTGTGGGGATCTCGCTCTGATCAGCTCAAAACTATCGAGCTCGAGGACTGGCCGACGGCTAGCGCTGATCCCAACAAGA
TTCACCCCCTCATTCGCATGGAAGGTCGCGCGGTCTTCAAGTGGGCTATGACTGACGTCGCCAAGCGCGCCGCCGAGGCC
ATCGCCGAGGCCGGAATCACCCCCGCCGACCTCGATGTCTTCATCCCCCATCAGGCTAACGACCGGATTACCGACGTCGT
GTCCCGCCACCTCAAGCTGCCTGAGTCAGTGACGGTGTGTCACGACATCGCGGATATGGGAAACACCTCCGCCGCATCCG
TGCCGATCGCTATTGACCGTATGCTTCAGCGTGGACAGGCCCACAGCGGGGACCTCGCCCTCATCATCGGATTCGGAGCC
GGGCTGGTCTACGCCGGCCAAGTCATCCGCCTCCCCTGA

Upstream 100 bases:

>100_bases
AGCGCAACTTGAAGGGAGTGGAGTTGTTCAACCTCAACACCCCCGATCAGATCCCGGCTGCCCGCGAGTTCATCACGACT
CACTCCAGCAAGGAGAATGC

Downstream 100 bases:

>100_bases
ACCCCACGTTCATCACGAGAAAAACACCCACAGACTTCGGGCGCACAGCCCGAGGATAACGACAAGAAGAGGAACAATCA
TCATGGCTGACAAAGACCAG

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 1; Beta-ketoacyl-ACP synthase III 1; KAS III 1 [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTAIKTRPVHGYSKFLSTGSARGSRVVTNKEMCTLIDSTPEWIEQRTGITERRWATNSETVASMGTTAARTALERSGLEA
SQIDAIIVATVSHHRPSPSLAAYIARELGLGDAAAFDLNGACAGFCYSTALADSMIRTGSANYVLVIGVEKLSEMTNLDD
RSTAFLFSDGAGAAIIGASDEPGIGPVVWGSRSDQLKTIELEDWPTASADPNKIHPLIRMEGRAVFKWAMTDVAKRAAEA
IAEAGITPADLDVFIPHQANDRITDVVSRHLKLPESVTVCHDIADMGNTSAASVPIAIDRMLQRGQAHSGDLALIIGFGA
GLVYAGQVIRLP

Sequences:

>Translated_332_residues
MTAIKTRPVHGYSKFLSTGSARGSRVVTNKEMCTLIDSTPEWIEQRTGITERRWATNSETVASMGTTAARTALERSGLEA
SQIDAIIVATVSHHRPSPSLAAYIARELGLGDAAAFDLNGACAGFCYSTALADSMIRTGSANYVLVIGVEKLSEMTNLDD
RSTAFLFSDGAGAAIIGASDEPGIGPVVWGSRSDQLKTIELEDWPTASADPNKIHPLIRMEGRAVFKWAMTDVAKRAAEA
IAEAGITPADLDVFIPHQANDRITDVVSRHLKLPESVTVCHDIADMGNTSAASVPIAIDRMLQRGQAHSGDLALIIGFGA
GLVYAGQVIRLP
>Mature_331_residues
TAIKTRPVHGYSKFLSTGSARGSRVVTNKEMCTLIDSTPEWIEQRTGITERRWATNSETVASMGTTAARTALERSGLEAS
QIDAIIVATVSHHRPSPSLAAYIARELGLGDAAAFDLNGACAGFCYSTALADSMIRTGSANYVLVIGVEKLSEMTNLDDR
STAFLFSDGAGAAIIGASDEPGIGPVVWGSRSDQLKTIELEDWPTASADPNKIHPLIRMEGRAVFKWAMTDVAKRAAEAI
AEAGITPADLDVFIPHQANDRITDVVSRHLKLPESVTVCHDIADMGNTSAASVPIAIDRMLQRGQAHSGDLALIIGFGAG
LVYAGQVIRLP

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=321, Percent_Identity=38.006230529595, Blast_Score=206, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35276; Mature: 35145

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00261 GLYCO_HORMONE_BETA_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIKTRPVHGYSKFLSTGSARGSRVVTNKEMCTLIDSTPEWIEQRTGITERRWATNSET
CCCCCCCCCCHHHHHHHCCCCCCCEEEECCHHEEEECCCHHHHHHHCCCCHHHCCCCCHH
VASMGTTAARTALERSGLEASQIDAIIVATVSHHRPSPSLAAYIARELGLGDAAAFDLNG
HHHHCCHHHHHHHHHCCCCHHHCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEECCCC
ACAGFCYSTALADSMIRTGSANYVLVIGVEKLSEMTNLDDRSTAFLFSDGAGAAIIGASD
CHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEECCCCEEEEECCC
EPGIGPVVWGSRSDQLKTIELEDWPTASADPNKIHPLIRMEGRAVFKWAMTDVAKRAAEA
CCCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCEEEHHHHHHHHHHHHHH
IAEAGITPADLDVFIPHQANDRITDVVSRHLKLPESVTVCHDIADMGNTSAASVPIAIDR
HHHCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
MLQRGQAHSGDLALIIGFGAGLVYAGQVIRLP
HHHHCCCCCCCEEEEEECCCCHHHCCEEEECC
>Mature Secondary Structure 
TAIKTRPVHGYSKFLSTGSARGSRVVTNKEMCTLIDSTPEWIEQRTGITERRWATNSET
CCCCCCCCCHHHHHHHCCCCCCCEEEECCHHEEEECCCHHHHHHHCCCCHHHCCCCCHH
VASMGTTAARTALERSGLEASQIDAIIVATVSHHRPSPSLAAYIARELGLGDAAAFDLNG
HHHHCCHHHHHHHHHCCCCHHHCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEECCCC
ACAGFCYSTALADSMIRTGSANYVLVIGVEKLSEMTNLDDRSTAFLFSDGAGAAIIGASD
CHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEECCCCEEEEECCC
EPGIGPVVWGSRSDQLKTIELEDWPTASADPNKIHPLIRMEGRAVFKWAMTDVAKRAAEA
CCCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCEEEHHHHHHHHHHHHHH
IAEAGITPADLDVFIPHQANDRITDVVSRHLKLPESVTVCHDIADMGNTSAASVPIAIDR
HHHCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
MLQRGQAHSGDLALIIGFGAGLVYAGQVIRLP
HHHHCCCCCCCEEEEEECCCCHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]