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The map label for this gene is pip [H]

Identifier: 50842416

GI number: 50842416

Start: 1013723

End: 1014646

Strand: Direct

Name: pip [H]

Synonym: PPA0932

Alternate gene names: 50842416

Gene position: 1013723-1014646 (Clockwise)

Preceding gene: 50842414

Following gene: 50842420

Centisome position: 39.59

GC content: 60.71

Gene sequence:

>924_bases
GTGACTCTTGCTACTTCCGAGCTGGACATCACCCCGCACCGGGATCTCTATCCGCCGATTGAGCCCTATGACACCCAGAT
GGTTGACGTGGGTGACGGTCAGCAGCTCTACGTCGAACAGTGCGGCAACCCTGAGGGCAAGCCGGTGGTTTTCCTGCATG
GTGGCCCTGGTGGTGGCGGCGGTACCGAGCGGCGTCGCTTCTTCAACCCCGATGCCTACCGCATCATCATCTTGGATCAG
CGGGGCTGCGGCCTGTCTACCCCGCACATTGCCCAGGCTCACACTCCACGTGAGATGGCCACCAATACGACGTGGAAACT
TGTTGAGGATCTTGAGAAGATCCGGGAGTTACTTGGCATTGAGCGTTGGGAGGTCTTTGGCGGATCGTGGGGATCCTGCT
TGTCGCTGGCTTACGCCGAGACCCATCCCGAGCGGGTGACCGAACTCGTGCTGCGTGGCATCTTTACCATGCGTGAGCAG
GAGTTGGACTGGTACTACAACTTCGGTGCCTCCGAGGTTTTCCCGGAGCTGTGGAACAAGTTCTGCGAGCCGCTGCGCCG
CGTCGGGCATGACTTTTCTCGTGACAACATAGCCGCCTACTACGACCTGCTGTGGGACGACGACCCCGACGTCCACGGTC
CTGCCGCGGTGGCCTGGACGACATGGGAGGGCGCGACGACCTCGTTGTCCTTCGACCGGTCCCACATCGAGGAGTTCTCG
GATCCAAACTTCGCGCTGGCCTTCGCCCGCATCGAGAACCACTACTTTGTCAATCATGGGTTCATGGTTGAGGGGCAGTT
GCTGCGTGATGCCCACAAGCTGGCCGACATCCCGACTGTTATCGTTCAGGGACGCTACGACATGTGCTGCCCCGACGTCA
CGGCCGTCGATTTGTCGCGAGCCTTGCCGAGCGCCGATCTGTGA

Upstream 100 bases:

>100_bases
CGCGGATGATCTGAGGCTGGTGGAGTGTGACGTCACGGCGAAATGGTAACCGTGTTGGCGCATATCATCGAGATGACGGT
CATGCCCACAGGAGGTTTCC

Downstream 100 bases:

>100_bases
ATCGTGATGGCAGGTCACTCTGCATTTGAGCCATTAATTGCCTCTGAACTAGTGAAGGTGTGTGACGAATTCGCCGAGCG
ATGAATTGTCGCCCAGGCGT

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTLATSELDITPHRDLYPPIEPYDTQMVDVGDGQQLYVEQCGNPEGKPVVFLHGGPGGGGGTERRRFFNPDAYRIIILDQ
RGCGLSTPHIAQAHTPREMATNTTWKLVEDLEKIRELLGIERWEVFGGSWGSCLSLAYAETHPERVTELVLRGIFTMREQ
ELDWYYNFGASEVFPELWNKFCEPLRRVGHDFSRDNIAAYYDLLWDDDPDVHGPAAVAWTTWEGATTSLSFDRSHIEEFS
DPNFALAFARIENHYFVNHGFMVEGQLLRDAHKLADIPTVIVQGRYDMCCPDVTAVDLSRALPSADL

Sequences:

>Translated_307_residues
MTLATSELDITPHRDLYPPIEPYDTQMVDVGDGQQLYVEQCGNPEGKPVVFLHGGPGGGGGTERRRFFNPDAYRIIILDQ
RGCGLSTPHIAQAHTPREMATNTTWKLVEDLEKIRELLGIERWEVFGGSWGSCLSLAYAETHPERVTELVLRGIFTMREQ
ELDWYYNFGASEVFPELWNKFCEPLRRVGHDFSRDNIAAYYDLLWDDDPDVHGPAAVAWTTWEGATTSLSFDRSHIEEFS
DPNFALAFARIENHYFVNHGFMVEGQLLRDAHKLADIPTVIVQGRYDMCCPDVTAVDLSRALPSADL
>Mature_306_residues
TLATSELDITPHRDLYPPIEPYDTQMVDVGDGQQLYVEQCGNPEGKPVVFLHGGPGGGGGTERRRFFNPDAYRIIILDQR
GCGLSTPHIAQAHTPREMATNTTWKLVEDLEKIRELLGIERWEVFGGSWGSCLSLAYAETHPERVTELVLRGIFTMREQE
LDWYYNFGASEVFPELWNKFCEPLRRVGHDFSRDNIAAYYDLLWDDDPDVHGPAAVAWTTWEGATTSLSFDRSHIEEFSD
PNFALAFARIENHYFVNHGFMVEGQLLRDAHKLADIPTVIVQGRYDMCCPDVTAVDLSRALPSADL

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 34755; Mature: 34624

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLATSELDITPHRDLYPPIEPYDTQMVDVGDGQQLYVEQCGNPEGKPVVFLHGGPGGGG
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEHHHCCCCCCCEEEEEECCCCCCC
GTERRRFFNPDAYRIIILDQRGCGLSTPHIAQAHTPREMATNTTWKLVEDLEKIRELLGI
CCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCC
ERWEVFGGSWGSCLSLAYAETHPERVTELVLRGIFTMREQELDWYYNFGASEVFPELWNK
CCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHH
FCEPLRRVGHDFSRDNIAAYYDLLWDDDPDVHGPAAVAWTTWEGATTSLSFDRSHIEEFS
HHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCCCEEEEECCHHHHHHCC
DPNFALAFARIENHYFVNHGFMVEGQLLRDAHKLADIPTVIVQGRYDMCCPDVTAVDLSR
CCCEEEEEEEECCEEEEECCEEEEHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHH
ALPSADL
CCCCCCC
>Mature Secondary Structure 
TLATSELDITPHRDLYPPIEPYDTQMVDVGDGQQLYVEQCGNPEGKPVVFLHGGPGGGG
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEHHHCCCCCCCEEEEEECCCCCCC
GTERRRFFNPDAYRIIILDQRGCGLSTPHIAQAHTPREMATNTTWKLVEDLEKIRELLGI
CCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCC
ERWEVFGGSWGSCLSLAYAETHPERVTELVLRGIFTMREQELDWYYNFGASEVFPELWNK
CCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHH
FCEPLRRVGHDFSRDNIAAYYDLLWDDDPDVHGPAAVAWTTWEGATTSLSFDRSHIEEFS
HHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCCCEEEEECCHHHHHHCC
DPNFALAFARIENHYFVNHGFMVEGQLLRDAHKLADIPTVIVQGRYDMCCPDVTAVDLSR
CCCEEEEEEEECCEEEEECCEEEEHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHH
ALPSADL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]