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The map label for this gene is hrcA

Identifier: 50842399

GI number: 50842399

Start: 996120

End: 997139

Strand: Direct

Name: hrcA

Synonym: PPA0915

Alternate gene names: 50842399

Gene position: 996120-997139 (Clockwise)

Preceding gene: 50842397

Following gene: 50842400

Centisome position: 38.91

GC content: 61.86

Gene sequence:

>1020_bases
GTGCTCGACGACCGCAAGCTCGACGTGCTCAAAGCCATCGTCACCGATTACGTCTCCAGCAAGGAGCCGGTAGGTTCAAA
GGCGCTGGTGGAACGCCACGGGTTGCGCGTTTCCCCGGCCACTGTCCGTAACGACATGGCCGTACTAGAGGAGGAGGGGT
ACATTACCCACCCCCACACCAGCGCCGGGCGCATCCCTACGGACAAGGGGTACCGCCTCTTCGTCGACCGCATCGCTACT
CTCAAGCCGCTCTCGGCGCCTGAGCGACGAGCCATTCAGGCATTCATGACTGGGGCGGTGGACCTTGACGACATCGTGCG
CCGTACTGTGCGCCTGCTTGCTCAAATCACCCACCAGGTAGCGATTATGCAGTACCCGGTGGCGACGACGGGGACGATTC
GTCACCTCGAATTGGTGAGTTTGTCGACCGACCGTATCCTTATCGTGCTCATCATGTCGTCGGGATCGGTAGAGCAGCAG
ATCGTTGAGCTTCCGGGCCACGACGAGCAGAGTCTTGCTGCACTTCGCACCCGGCTAAATGAGACTCTCGTCGGATTGAC
AGTCGCTGAAGCGGCCGACTCGCTCAACCGCTTTCTTGACGACCTGGGACCGGCCGAAGGGCCTCGGGCAGCGTCGGTGA
TTGCTACCGTTCTCGAGATCCTTGCCGTCGACCCATCTGCTCGGGTTGTGGTCGCCGGGGTTCCCAATCTCACCGCATTC
GGTGCACAGTGGGAGACAGCGGTACGTCCCGTCCTTGAGGCCCTTGAAGAGCAGGTCGTCCTTATGCGACTGCTCGGCGA
GGCAACCGCGGGGGAGGCTGGCGAGGTTACGGTCCGCATCGGCGCCGAGAACACCGATGTACCTTTCCAATCGACCTCGT
TAGTGGCGAGCACCTACGGTCCCGAGGATGCCTTGTCGAGTCTTGGCGTCGTCGGGCCGATCCGAATGGACTACCCCTCA
ACCATGGCAGCTGTGCGAGCCGTGGCCCGTTATGTGGGCCGGTTCCTGGCAGAAGGATGA

Upstream 100 bases:

>100_bases
AGAGGCAGGAGGACCGAGTGTGAACGCGATAAGGTGGCACTCGGCACCCGAGAGTGCCAAAGTGGGATGTGCATTTGGCC
GGATCGCGTGAGGAGGGGTT

Downstream 100 bases:

>100_bases
TTCTTGAGTAACGACTACTACGAGATTCTTGGCGTTTCCCATGATGCGAGTGCCGACGAGATCAAGAAGGCGTATCGCCG
TAAGGCTATGAAACTCCACC

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MLDDRKLDVLKAIVTDYVSSKEPVGSKALVERHGLRVSPATVRNDMAVLEEEGYITHPHTSAGRIPTDKGYRLFVDRIAT
LKPLSAPERRAIQAFMTGAVDLDDIVRRTVRLLAQITHQVAIMQYPVATTGTIRHLELVSLSTDRILIVLIMSSGSVEQQ
IVELPGHDEQSLAALRTRLNETLVGLTVAEAADSLNRFLDDLGPAEGPRAASVIATVLEILAVDPSARVVVAGVPNLTAF
GAQWETAVRPVLEALEEQVVLMRLLGEATAGEAGEVTVRIGAENTDVPFQSTSLVASTYGPEDALSSLGVVGPIRMDYPS
TMAAVRAVARYVGRFLAEG

Sequences:

>Translated_339_residues
MLDDRKLDVLKAIVTDYVSSKEPVGSKALVERHGLRVSPATVRNDMAVLEEEGYITHPHTSAGRIPTDKGYRLFVDRIAT
LKPLSAPERRAIQAFMTGAVDLDDIVRRTVRLLAQITHQVAIMQYPVATTGTIRHLELVSLSTDRILIVLIMSSGSVEQQ
IVELPGHDEQSLAALRTRLNETLVGLTVAEAADSLNRFLDDLGPAEGPRAASVIATVLEILAVDPSARVVVAGVPNLTAF
GAQWETAVRPVLEALEEQVVLMRLLGEATAGEAGEVTVRIGAENTDVPFQSTSLVASTYGPEDALSSLGVVGPIRMDYPS
TMAAVRAVARYVGRFLAEG
>Mature_339_residues
MLDDRKLDVLKAIVTDYVSSKEPVGSKALVERHGLRVSPATVRNDMAVLEEEGYITHPHTSAGRIPTDKGYRLFVDRIAT
LKPLSAPERRAIQAFMTGAVDLDDIVRRTVRLLAQITHQVAIMQYPVATTGTIRHLELVSLSTDRILIVLIMSSGSVEQQ
IVELPGHDEQSLAALRTRLNETLVGLTVAEAADSLNRFLDDLGPAEGPRAASVIATVLEILAVDPSARVVVAGVPNLTAF
GAQWETAVRPVLEALEEQVVLMRLLGEATAGEAGEVTVRIGAENTDVPFQSTSLVASTYGPEDALSSLGVVGPIRMDYPS
TMAAVRAVARYVGRFLAEG

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_PROAC (Q6A998)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_055626.1
- ProteinModelPortal:   Q6A998
- SMR:   Q6A998
- GeneID:   2932581
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA0915
- NMPDR:   fig|267747.1.peg.903
- HOGENOM:   HBG729878
- OMA:   RYLTAFL
- ProtClustDB:   PRK00082
- BioCyc:   PACN267747:PPA0915-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00081
- InterPro:   IPR001034
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF01628 HrcA; PF08220 HTH_DeoR

EC number: NA

Molecular weight: Translated: 36421; Mature: 36421

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDDRKLDVLKAIVTDYVSSKEPVGSKALVERHGLRVSPATVRNDMAVLEEEGYITHPHT
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCC
SAGRIPTDKGYRLFVDRIATLKPLSAPERRAIQAFMTGAVDLDDIVRRTVRLLAQITHQV
CCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AIMQYPVATTGTIRHLELVSLSTDRILIVLIMSSGSVEQQIVELPGHDEQSLAALRTRLN
HHHHCCCCCCCCEEEEEEEEECCCCEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHH
ETLVGLTVAEAADSLNRFLDDLGPAEGPRAASVIATVLEILAVDPSARVVVAGVPNLTAF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHC
GAQWETAVRPVLEALEEQVVLMRLLGEATAGEAGEVTVRIGAENTDVPFQSTSLVASTYG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHEEECCC
PEDALSSLGVVGPIRMDYPSTMAAVRAVARYVGRFLAEG
CHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDDRKLDVLKAIVTDYVSSKEPVGSKALVERHGLRVSPATVRNDMAVLEEEGYITHPHT
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCC
SAGRIPTDKGYRLFVDRIATLKPLSAPERRAIQAFMTGAVDLDDIVRRTVRLLAQITHQV
CCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AIMQYPVATTGTIRHLELVSLSTDRILIVLIMSSGSVEQQIVELPGHDEQSLAALRTRLN
HHHHCCCCCCCCEEEEEEEEECCCCEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHH
ETLVGLTVAEAADSLNRFLDDLGPAEGPRAASVIATVLEILAVDPSARVVVAGVPNLTAF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHC
GAQWETAVRPVLEALEEQVVLMRLLGEATAGEAGEVTVRIGAENTDVPFQSTSLVASTYG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHEEECCC
PEDALSSLGVVGPIRMDYPSTMAAVRAVARYVGRFLAEG
CHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA