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The map label for this gene is suhB [H]

Identifier: 50842397

GI number: 50842397

Start: 994525

End: 995286

Strand: Direct

Name: suhB [H]

Synonym: PPA0913

Alternate gene names: 50842397

Gene position: 994525-995286 (Clockwise)

Preceding gene: 50842396

Following gene: 50842399

Centisome position: 38.84

GC content: 58.79

Gene sequence:

>762_bases
ATGAGTATTGACGTCGACGCGGTGTCTGACCTCATCCGGGATGTGAGTGCCAGGGTTATCGATCCCCGGTTCCGGACCCT
CGACGATCATCAAATCCACCAGAAAAAGCCTGGGGACTTCGTTACTGATGCCGATCGTCAGGCCGAGCGCGAGCTGGGTG
CCGCTGTGACCAAGTATGCCGGCGGTATTGTCGTGGGGGAGGAATCAGCCTTCGCCGACCCAACCATCCTTGATGCCGTT
TCCGATGCTGACCTGGCCTGGGTCATCGACCCCATTGATGGCACCAAGAACTTCGTGCACGGGTCTGTTGATCACGGCGT
CATGCTTGCTCAGCTCAACCGCGGTGAAACAGTCAGAGGATGGATATGGCAGCCGCAGCACGGGCACATGTGGTTCGCTG
AGCATGGCGCCGGAGTGACGTGCGATGGTGATGAGGTGACGCGGGGGGATTCCCACTCTCCGGTTCGTGCTGCCACCACC
CATGAGGTCTACAAGATTCCCTCGCCTGTGGTGGAATGGCGAATGGCGAAATGGTGCTGTGCGGTGGATTATCCGTTGGT
GTGCCAGGACGAGAACGATGTCACCGTCTATCAACACTCTTACCCGTGGGATCACCTTCCTGGCGCGCTCATGGTACGAG
AGGTCGGCGGAGTAGTGCGTACTGTCGAGGGCGCGGAATATGGCCCTCGAGAAACCTCCGGAAAGCTCATTGTTGCTGCC
GACGAAGAGGCTTATGAGACAGTTGCCAGACTGCTGCGCTGA

Upstream 100 bases:

>100_bases
ACTGGCACGATTTAGACCCCCGCTTTAACACGGAGATGGAGAAACTTATCGATTTCGTCACGTGTGACCATGTTGACGAG
CTGGACAATGAGGAGATGGC

Downstream 100 bases:

>100_bases
ATCTCTTCGCTGTGGCCCTCACGGTAGAGGGATATGGCGGTCGGTGAGCGGGATATTCGTGGGAATTCGCTCGGCGAGCT
GGGCACGCTGATTCATAACG

Product: inositol monophosphatase family protein

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSIDVDAVSDLIRDVSARVIDPRFRTLDDHQIHQKKPGDFVTDADRQAERELGAAVTKYAGGIVVGEESAFADPTILDAV
SDADLAWVIDPIDGTKNFVHGSVDHGVMLAQLNRGETVRGWIWQPQHGHMWFAEHGAGVTCDGDEVTRGDSHSPVRAATT
HEVYKIPSPVVEWRMAKWCCAVDYPLVCQDENDVTVYQHSYPWDHLPGALMVREVGGVVRTVEGAEYGPRETSGKLIVAA
DEEAYETVARLLR

Sequences:

>Translated_253_residues
MSIDVDAVSDLIRDVSARVIDPRFRTLDDHQIHQKKPGDFVTDADRQAERELGAAVTKYAGGIVVGEESAFADPTILDAV
SDADLAWVIDPIDGTKNFVHGSVDHGVMLAQLNRGETVRGWIWQPQHGHMWFAEHGAGVTCDGDEVTRGDSHSPVRAATT
HEVYKIPSPVVEWRMAKWCCAVDYPLVCQDENDVTVYQHSYPWDHLPGALMVREVGGVVRTVEGAEYGPRETSGKLIVAA
DEEAYETVARLLR
>Mature_252_residues
SIDVDAVSDLIRDVSARVIDPRFRTLDDHQIHQKKPGDFVTDADRQAERELGAAVTKYAGGIVVGEESAFADPTILDAVS
DADLAWVIDPIDGTKNFVHGSVDHGVMLAQLNRGETVRGWIWQPQHGHMWFAEHGAGVTCDGDEVTRGDSHSPVRAATTH
EVYKIPSPVVEWRMAKWCCAVDYPLVCQDENDVTVYQHSYPWDHLPGALMVREVGGVVRTVEGAEYGPRETSGKLIVAAD
EEAYETVARLLR

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=226, Percent_Identity=26.1061946902655, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI221625487, Length=226, Percent_Identity=26.1061946902655, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788882, Length=226, Percent_Identity=28.7610619469027, Blast_Score=75, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24664918, Length=241, Percent_Identity=26.9709543568465, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357957, Length=235, Percent_Identity=26.8085106382979, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24664926, Length=235, Percent_Identity=25.531914893617, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 27915; Mature: 27784

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00380 RHODANESE_1 ; PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDVDAVSDLIRDVSARVIDPRFRTLDDHQIHQKKPGDFVTDADRQAERELGAAVTKYA
CCCCHHHHHHHHHHHHHHEECCHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHC
GGIVVGEESAFADPTILDAVSDADLAWVIDPIDGTKNFVHGSVDHGVMLAQLNRGETVRG
CCEEEECCCCCCCCHHHHHCCCCCEEEEEECCCCCCHHCCCCCCCCEEEEEECCCCEEEE
WIWQPQHGHMWFAEHGAGVTCDGDEVTRGDSHSPVRAATTHEVYKIPSPVVEWRMAKWCC
EEECCCCCCEEEEECCCCEEECCCCCCCCCCCCCEEECCCCCEEECCCHHHHHHHHHHHE
AVDYPLVCQDENDVTVYQHSYPWDHLPGALMVREVGGVVRTVEGAEYGPRETSGKLIVAA
ECCCCEEEECCCCEEEEECCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCEEEEE
DEEAYETVARLLR
CHHHHHHHHHHHC
>Mature Secondary Structure 
SIDVDAVSDLIRDVSARVIDPRFRTLDDHQIHQKKPGDFVTDADRQAERELGAAVTKYA
CCCHHHHHHHHHHHHHHEECCHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHC
GGIVVGEESAFADPTILDAVSDADLAWVIDPIDGTKNFVHGSVDHGVMLAQLNRGETVRG
CCEEEECCCCCCCCHHHHHCCCCCEEEEEECCCCCCHHCCCCCCCCEEEEEECCCCEEEE
WIWQPQHGHMWFAEHGAGVTCDGDEVTRGDSHSPVRAATTHEVYKIPSPVVEWRMAKWCC
EEECCCCCCEEEEECCCCEEECCCCCCCCCCCCCEEECCCCCEEECCCHHHHHHHHHHHE
AVDYPLVCQDENDVTVYQHSYPWDHLPGALMVREVGGVVRTVEGAEYGPRETSGKLIVAA
ECCCCEEEECCCCEEEEECCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCEEEEE
DEEAYETVARLLR
CHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]