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The map label for this gene is entC [H]

Identifier: 50842388

GI number: 50842388

Start: 985810

End: 987165

Strand: Reverse

Name: entC [H]

Synonym: PPA0904

Alternate gene names: 50842388

Gene position: 987165-985810 (Counterclockwise)

Preceding gene: 50842389

Following gene: 50842384

Centisome position: 38.56

GC content: 66.22

Gene sequence:

>1356_bases
TTGACTTCTTGTCGCGGTCGGTCGAATTTGACGCATCACTTCTTGGGCGTTGGGTGCGACCACATTGTTTGCGTGCAACG
TCGTGGTCGCACCCGTAGTCCGGGTCTCCCGCAAAGCATTGTGTGGGCTTCAGCAAGTAAGGTCGAGCCCGTGCTAAACC
TGCTGCCCTGCTCTGACACCGTCTCGGCCCTGCCGGGAACGGCCTGGCTTGATGAAGTGCTCCACTGGGTGCCCGAGGGC
GTCGACCCGTGGATCTGGTTGGCCCCCGACTCCGACGACGCCCCCGCCATGGTCGGCTGGGGCGTCACTCGACGCTTCAC
CGCATCCGGTCACGGAGCGGTCGAGTCCGCCTGGCGCCGGATGGCGTCCGAAGGGCAGGACCTCTTCGCCTTCGGCTCGT
TTCCCTTCTCGCGCACCCAGGAAGGGTTCCTCGTGGTCCCGCAGGTGCTCATCCGACGTCGTCACCTCGGGGGGCCGACC
GAGGTGACGAATCACCAGCGGCTCACCCGACGAACGTGGGGGCCCGAGCCGAAGAAACACCTGACCCGTAGACCGGCCAT
CGACGAAGCCACATGGACAGCGTCGGTTACCGCGGTGACCCAGCAGCTAGACCACGACGGGCAGCTCGAGAAGGTGGTAT
TGGCCGGGGCGGTCGACATCACCTCTGAGGTGCCCATCGACCGCAGTCAGGTCGCCTCACGACTGGCCGCACGGTTCCCC
GGCTGCTGGACGTACAGCCACGACGGGCTGGTGGGGGCAACCCCCGAGCTGCTCGTCGACTGCCGCGACGGGCTCTTCCG
CTGTCGGGTGCTGGCCGGCACCCGCAAACCGGCCTGGGCCCACGAGCTGCTCGACAACCCCAAGGAACGCCACGAACACG
AGCTGGCGGTGGCCTCGGTCACCGGGCGACTGGCCCAGGCCGGGCTGACTGATCCTGTCATCCGCGGTCCTTTCCGTTTG
GAGCTCCCCAATGTCGTCCACTTGGCGACCGATGTCACCGCTAGGGTGAACGGCTCCAACGCGGCGCGCATCGTCGATGC
AATGCACCCGACCGCCGCCGTGTGCGGCACCCCCCGCGAGGCCTCTTACAAGCTCATCGCGCAGATAGAGCACTTGGACC
GGGGACGGTTCGCCGGGCCGGTGGGCTGGATGAGCTCGGACGGGTCGGGACAGTGGGCCCTAGCGCTGCGCTGTGGACAA
TTCAGTGAGGACTCGCGCCAGGTGAGAATGTTCGCTGGAGCCGGAATCTTGCCAACCTCTGACCCTGCTAAGGAGTGGAT
CGAGGTTGGCGCCAAGATGGAAGCCTTCGGCGACGCCCTGCCCAACGGTCAGGTGAGTGGTACCGAAACGACCTGA

Upstream 100 bases:

>100_bases
TTTCGTCCGCAGTTACTATGCCGAATTTCATGATCGCGTCTCCCCATTGACTTTGACGATTTTCTGCGTCTGGTCGCCGT
GGGTGAACTTCTCGAAAATC

Downstream 100 bases:

>100_bases
CGACCCACAACCGGTTCGTCGAGGAACTGGAGGTCGTCTGGAGAGACCCTCCGGTGACTCGCTCCGAGGGCGTGCGCGAG
GGCGGCGGAATCGAGACGCT

Product: isochorismate synthetase, enterochelin biosynthesis

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MTSCRGRSNLTHHFLGVGCDHIVCVQRRGRTRSPGLPQSIVWASASKVEPVLNLLPCSDTVSALPGTAWLDEVLHWVPEG
VDPWIWLAPDSDDAPAMVGWGVTRRFTASGHGAVESAWRRMASEGQDLFAFGSFPFSRTQEGFLVVPQVLIRRRHLGGPT
EVTNHQRLTRRTWGPEPKKHLTRRPAIDEATWTASVTAVTQQLDHDGQLEKVVLAGAVDITSEVPIDRSQVASRLAARFP
GCWTYSHDGLVGATPELLVDCRDGLFRCRVLAGTRKPAWAHELLDNPKERHEHELAVASVTGRLAQAGLTDPVIRGPFRL
ELPNVVHLATDVTARVNGSNAARIVDAMHPTAAVCGTPREASYKLIAQIEHLDRGRFAGPVGWMSSDGSGQWALALRCGQ
FSEDSRQVRMFAGAGILPTSDPAKEWIEVGAKMEAFGDALPNGQVSGTETT

Sequences:

>Translated_451_residues
MTSCRGRSNLTHHFLGVGCDHIVCVQRRGRTRSPGLPQSIVWASASKVEPVLNLLPCSDTVSALPGTAWLDEVLHWVPEG
VDPWIWLAPDSDDAPAMVGWGVTRRFTASGHGAVESAWRRMASEGQDLFAFGSFPFSRTQEGFLVVPQVLIRRRHLGGPT
EVTNHQRLTRRTWGPEPKKHLTRRPAIDEATWTASVTAVTQQLDHDGQLEKVVLAGAVDITSEVPIDRSQVASRLAARFP
GCWTYSHDGLVGATPELLVDCRDGLFRCRVLAGTRKPAWAHELLDNPKERHEHELAVASVTGRLAQAGLTDPVIRGPFRL
ELPNVVHLATDVTARVNGSNAARIVDAMHPTAAVCGTPREASYKLIAQIEHLDRGRFAGPVGWMSSDGSGQWALALRCGQ
FSEDSRQVRMFAGAGILPTSDPAKEWIEVGAKMEAFGDALPNGQVSGTETT
>Mature_450_residues
TSCRGRSNLTHHFLGVGCDHIVCVQRRGRTRSPGLPQSIVWASASKVEPVLNLLPCSDTVSALPGTAWLDEVLHWVPEGV
DPWIWLAPDSDDAPAMVGWGVTRRFTASGHGAVESAWRRMASEGQDLFAFGSFPFSRTQEGFLVVPQVLIRRRHLGGPTE
VTNHQRLTRRTWGPEPKKHLTRRPAIDEATWTASVTAVTQQLDHDGQLEKVVLAGAVDITSEVPIDRSQVASRLAARFPG
CWTYSHDGLVGATPELLVDCRDGLFRCRVLAGTRKPAWAHELLDNPKERHEHELAVASVTGRLAQAGLTDPVIRGPFRLE
LPNVVHLATDVTARVNGSNAARIVDAMHPTAAVCGTPREASYKLIAQIEHLDRGRFAGPVGWMSSDGSGQWALALRCGQF
SEDSRQVRMFAGAGILPTSDPAKEWIEVGAKMEAFGDALPNGQVSGTETT

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=319, Percent_Identity=33.8557993730408, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI87082077, Length=423, Percent_Identity=26.9503546099291, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 49086; Mature: 48955

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSCRGRSNLTHHFLGVGCDHIVCVQRRGRTRSPGLPQSIVWASASKVEPVLNLLPCSDT
CCCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCCCHH
VSALPGTAWLDEVLHWVPEGVDPWIWLAPDSDDAPAMVGWGVTRRFTASGHGAVESAWRR
HHHCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEECCCCEEEECCCCHHHHHHHHH
MASEGQDLFAFGSFPFSRTQEGFLVVPQVLIRRRHLGGPTEVTNHQRLTRRTWGPEPKKH
HHHCCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCHHHH
LTRRPAIDEATWTASVTAVTQQLDHDGQLEKVVLAGAVDITSEVPIDRSQVASRLAARFP
HHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCEECCCCCCCCHHHHHHHHHHHCC
GCWTYSHDGLVGATPELLVDCRDGLFRCRVLAGTRKPAWAHELLDNPKERHEHELAVASV
CCEEECCCCCCCCCHHHHHHHHHHHEEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHH
TGRLAQAGLTDPVIRGPFRLELPNVVHLATDVTARVNGSNAARIVDAMHPTAAVCGTPRE
HHHHHHCCCCCCHHCCCEEECCCCEEEEECCEEEEECCCCHHHHHHHCCCCHHHCCCCCH
ASYKLIAQIEHLDRGRFAGPVGWMSSDGSGQWALALRCGQFSEDSRQVRMFAGAGILPTS
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCC
DPAKEWIEVGAKMEAFGDALPNGQVSGTETT
CHHHHHHHHCCHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSCRGRSNLTHHFLGVGCDHIVCVQRRGRTRSPGLPQSIVWASASKVEPVLNLLPCSDT
CCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCCCHH
VSALPGTAWLDEVLHWVPEGVDPWIWLAPDSDDAPAMVGWGVTRRFTASGHGAVESAWRR
HHHCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEECCCCEEEECCCCHHHHHHHHH
MASEGQDLFAFGSFPFSRTQEGFLVVPQVLIRRRHLGGPTEVTNHQRLTRRTWGPEPKKH
HHHCCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCHHHH
LTRRPAIDEATWTASVTAVTQQLDHDGQLEKVVLAGAVDITSEVPIDRSQVASRLAARFP
HHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCEECCCCCCCCHHHHHHHHHHHCC
GCWTYSHDGLVGATPELLVDCRDGLFRCRVLAGTRKPAWAHELLDNPKERHEHELAVASV
CCEEECCCCCCCCCHHHHHHHHHHHEEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHH
TGRLAQAGLTDPVIRGPFRLELPNVVHLATDVTARVNGSNAARIVDAMHPTAAVCGTPRE
HHHHHHCCCCCCHHCCCEEECCCCEEEEECCEEEEECCCCHHHHHHHCCCCHHHCCCCCH
ASYKLIAQIEHLDRGRFAGPVGWMSSDGSGQWALALRCGQFSEDSRQVRMFAGAGILPTS
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCC
DPAKEWIEVGAKMEAFGDALPNGQVSGTETT
CHHHHHHHHCCHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]