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The map label for this gene is php [C]

Identifier: 50842366

GI number: 50842366

Start: 956567

End: 957559

Strand: Direct

Name: php [C]

Synonym: PPA0879

Alternate gene names: 50842366

Gene position: 956567-957559 (Clockwise)

Preceding gene: 50842362

Following gene: 50842367

Centisome position: 37.36

GC content: 59.92

Gene sequence:

>993_bases
ATGGCCGTCGTTCGTACCATCAATGGCGACGTTTCACCCGACACCCTCGGCGTCGTCAATGCCCACGATCACCTCATCCG
CGTCGGAGCAGGGGAGGTCTACATCGACCCTGACCACTTGCTTGACGACGTCGACAAGGCAGCCCAGGAGGCTACATATT
TCGTCGAGGCCTCTAAGAGCTGGGCCGCTGGGGGAACCATCATCGACATGTGCCCGGCCTCCTCAGGCCGCGGCGTGCTC
AAAACCCTCCAGGTCGTCGAGAAGGTTCCGGGGCTGCAGGTCGTCCAAGCCACCGGATTCCACCAGCAGAAGGTCTACCT
CGAGTGGCGTCAGAGCTGGGTCAACCAGTACACCGTCACTCAGATCGCCGATCTACTCATCGCCGACATCGTTGAGGGCA
TCGACCGTTTCGACTATATGGGCCCCATTGTCGAGCGCACCAACGTCAAGGCGGGCGTCATCAAGTGGGCCACCGCCTAC
GGCAAGATCACCGAGTGGGAAAAGAAGTCCGGCCAAGCCGTCGCCATCGCATCTAAGGAGACCGGCTGTCCCATTAACAC
CCACGTGACGGCCGGAACTTGTGGCCCTGAGCAGGCAAGATTCCTTGTTGACCAGGGTGTTGATCCGGCCAAAATCGCTA
TCGGCCATATGCAGCGCAACTGGGATCCCTGGGTTCACGAGCAGATCTGCAAGCTCGGCTGCTACGTCGAGCTGGACGGC
ACTAACCGCATCAAGTACGTCCCGGATAACACCCGCGTCAACCTCGTGAAGACCCTCGGTGAGAAGGGCTACGGCAAGCA
GATTCTGTTGGGCACCGACTCCGGTAAGGCCTCTTACCAAAAGGTTTACGGTTCGGTCTCAGGCATCGATTACGATCCGG
CCGTCTTCTGTCCACGTCTCGTCGAAGACGAAGGCGTCGACCGCGACTACGTTAACGACCTCCTCATCAACAACGCGGCC
ACCTTCTTCGGCTTCGAGCCGCTGGCCGGGTGA

Upstream 100 bases:

>100_bases
TTAGGATGAATTCACATGTGTGAACTCATGGCCTTGCGGGGTTGCTGTGGCGGCGGCTCAATGGTTCCCGTCACATAGTC
GTGAGAGAGGAATCACTCCA

Downstream 100 bases:

>100_bases
CGACGATGCCACGACTTCAGATCGCTCTTGACACCTATGATCTGCCGTCGGCCCTGGCTCCGTTGGCCACCGCCGTCGAC
CAGATCGACATCATCGAGTG

Product: putative phosphotriesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MAVVRTINGDVSPDTLGVVNAHDHLIRVGAGEVYIDPDHLLDDVDKAAQEATYFVEASKSWAAGGTIIDMCPASSGRGVL
KTLQVVEKVPGLQVVQATGFHQQKVYLEWRQSWVNQYTVTQIADLLIADIVEGIDRFDYMGPIVERTNVKAGVIKWATAY
GKITEWEKKSGQAVAIASKETGCPINTHVTAGTCGPEQARFLVDQGVDPAKIAIGHMQRNWDPWVHEQICKLGCYVELDG
TNRIKYVPDNTRVNLVKTLGEKGYGKQILLGTDSGKASYQKVYGSVSGIDYDPAVFCPRLVEDEGVDRDYVNDLLINNAA
TFFGFEPLAG

Sequences:

>Translated_330_residues
MAVVRTINGDVSPDTLGVVNAHDHLIRVGAGEVYIDPDHLLDDVDKAAQEATYFVEASKSWAAGGTIIDMCPASSGRGVL
KTLQVVEKVPGLQVVQATGFHQQKVYLEWRQSWVNQYTVTQIADLLIADIVEGIDRFDYMGPIVERTNVKAGVIKWATAY
GKITEWEKKSGQAVAIASKETGCPINTHVTAGTCGPEQARFLVDQGVDPAKIAIGHMQRNWDPWVHEQICKLGCYVELDG
TNRIKYVPDNTRVNLVKTLGEKGYGKQILLGTDSGKASYQKVYGSVSGIDYDPAVFCPRLVEDEGVDRDYVNDLLINNAA
TFFGFEPLAG
>Mature_329_residues
AVVRTINGDVSPDTLGVVNAHDHLIRVGAGEVYIDPDHLLDDVDKAAQEATYFVEASKSWAAGGTIIDMCPASSGRGVLK
TLQVVEKVPGLQVVQATGFHQQKVYLEWRQSWVNQYTVTQIADLLIADIVEGIDRFDYMGPIVERTNVKAGVIKWATAYG
KITEWEKKSGQAVAIASKETGCPINTHVTAGTCGPEQARFLVDQGVDPAKIAIGHMQRNWDPWVHEQICKLGCYVELDGT
NRIKYVPDNTRVNLVKTLGEKGYGKQILLGTDSGKASYQKVYGSVSGIDYDPAVFCPRLVEDEGVDRDYVNDLLINNAAT
FFGFEPLAG

Specific function: Its Real Enzymatic Activity Is Not Yet Known. It Was Tested For General Esterase, Aminopeptidase, Sulfatase, Phosphatase, Carbonic Anhydrase, Phosphodiesterase, And Phosphotriesterase Activities With The Following Substrates: P- Nitrophenyl Acetate, L-Ala

COG id: COG1735

COG function: function code R; Predicted metal-dependent hydrolase with the TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphotriesterase family [H]

Homologues:

Organism=Homo sapiens, GI20070186, Length=298, Percent_Identity=25.1677852348993, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI47933341, Length=298, Percent_Identity=25.1677852348993, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1789780, Length=318, Percent_Identity=29.2452830188679, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001559 [H]

Pfam domain/function: PF02126 PTE [H]

EC number: NA

Molecular weight: Translated: 36091; Mature: 35960

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS01323 PHOSPHOTRIESTERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVVRTINGDVSPDTLGVVNAHDHLIRVGAGEVYIDPDHLLDDVDKAAQEATYFVEASKS
CEEEEECCCCCCCCCEEEEECCCCEEEECCCEEEECHHHHHHHHHHHHHHHEEEEECCCC
WAAGGTIIDMCPASSGRGVLKTLQVVEKVPGLQVVQATGFHQQKVYLEWRQSWVNQYTVT
CCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHH
QIADLLIADIVEGIDRFDYMGPIVERTNVKAGVIKWATAYGKITEWEKKSGQAVAIASKE
HHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHCCCCHHHCCCCCEEEEECCC
TGCPINTHVTAGTCGPEQARFLVDQGVDPAKIAIGHMQRNWDPWVHEQICKLGCYVELDG
CCCCCCCEEEECCCCHHHHHHHHHCCCCHHHHEEHHHHCCCCHHHHHHHHHHCCEEEECC
TNRIKYVPDNTRVNLVKTLGEKGYGKQILLGTDSGKASYQKVYGSVSGIDYDPAVFCPRL
CCEEEECCCCCCCHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCHHHHCCHH
VEDEGVDRDYVNDLLINNAATFFGFEPLAG
HCCCCCCHHHHHHHHHCCCHHHCCCCCCCC
>Mature Secondary Structure 
AVVRTINGDVSPDTLGVVNAHDHLIRVGAGEVYIDPDHLLDDVDKAAQEATYFVEASKS
EEEEECCCCCCCCCEEEEECCCCEEEECCCEEEECHHHHHHHHHHHHHHHEEEEECCCC
WAAGGTIIDMCPASSGRGVLKTLQVVEKVPGLQVVQATGFHQQKVYLEWRQSWVNQYTVT
CCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHH
QIADLLIADIVEGIDRFDYMGPIVERTNVKAGVIKWATAYGKITEWEKKSGQAVAIASKE
HHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHCCCCHHHCCCCCEEEEECCC
TGCPINTHVTAGTCGPEQARFLVDQGVDPAKIAIGHMQRNWDPWVHEQICKLGCYVELDG
CCCCCCCEEEECCCCHHHHHHHHHCCCCHHHHEEHHHHCCCCHHHHHHHHHHCCEEEECC
TNRIKYVPDNTRVNLVKTLGEKGYGKQILLGTDSGKASYQKVYGSVSGIDYDPAVFCPRL
CCEEEECCCCCCCHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCHHHHCCHH
VEDEGVDRDYVNDLLINNAATFFGFEPLAG
HCCCCCCHHHHHHHHHCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]