| Definition | Propionibacterium acnes KPA171202, complete genome. |
|---|---|
| Accession | NC_006085 |
| Length | 2,560,265 |
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The map label for this gene is uvrA [H]
Identifier: 50842363
GI number: 50842363
Start: 952257
End: 954596
Strand: Reverse
Name: uvrA [H]
Synonym: PPA0877
Alternate gene names: 50842363
Gene position: 954596-952257 (Counterclockwise)
Preceding gene: 50842364
Following gene: 50842360
Centisome position: 37.29
GC content: 56.45
Gene sequence:
>2340_bases ATGCGTAACCTCAGGAAGGATATCGTTTCGCGCAGCTCTGTGGGCTCGATCCAAATCCACGGTGCCAAGACACATAATCT GCGAGACGTCACAGTTTGCATCCCCAAGCATGCGCTTGTCGGCGTCGCCGGGGTTTCTGGTTCTGGAAAAACTTCCTTGG TATCTACTCTGGCAGTCGGGGCACAACAAGCCGTGTCCTCGCTTTTTCCGGCTTTTGTGCAAGCTAGGTTGAATACCTTG GAACCTGGCCTGGTCGATGGCTTGCAAGGTCTGACCTTCACCGCGATCGTCGGGCAAAAGAAATTCAGTAGAAATGCGCG CTCATCAGTGAGCACGGCCAGCGGTATCGCGCCATATCTGCGCCTGCTGTTCTCCCGGTCAGGTTCTCCCTCTGCAGGTT ATTCTCCTTCGTACTCACCGAATGATCCGCGCGGCATGTGCATGGACTGCTCCGGCTTGGGCTATGTGGATGATATCGAC CTGCAAGAGCTTATCGCCCCCGACAGGAGCTTGAATGAAGGAGCTGTCCGCTTCCCCTCGTTCGAACCTGGAACTTATCG ATGGAAACGTCTAGTGTGTTCTGGACTCTTCGACCCCGATGTGCCGTGGAAAGAACTGCCCGAGGCATCACGCAAGCTGC TCCTTCACGGCCAGGGAGTCCGTTTGGAGCGTCCCCTCACCGGCTATCCCAAACATGGCATCTTCGATGGGATCATTCCT CGCCTTAAAGCGTCATATTTGGAAAAAGCCAACGCGAAAACAACCGAGAAGGAAGATGCCGCACTGCGTAGGATCGTGAA GCGGGTCGTATGTCCTCATTGCCACGGTCAGCGCATTAACGAGGCAGCCCGCGCCAGTCGAATCGAGGGGCTCAACATTG CTGAAGCATCCCATTTGAGTATCGATGAATGCATTGCCTTTATCAAAACCATAACCGACGAGATAACTGAGGCACCCCGC CAAGCGGTTTTAGCAAGGCTGAACAACATGCGCGACATCGGCCTGGGGTATCTCAGCCTCGACCGTCCGACGGACACCCT TTCCGGCGGTGAAGCTCAACGGCTACGCCTCGTTAGCCTCTTGGACGCACCCATCACCGACGCAACTTTCGTGATGGATG AACCCTCAAGTGGACTGCACCCTGCCGACATCGAACGCCTGCTACGGTCGCTAAGGAAACTGCGGGACTCTGGGAACACT GTGATCATCGTCGAGCACAATCTGCAGGTCCTGGCCGCCTGCGATCATGTCGTTGAGCTCGGGCCGGGCGCGGGAGATGA TGGCGGACGGGTTCTATTTGAGGGCAGCCCTCGGAGTTTGACCCGTAGCGACACCCCAACGGGAAAAGCACTGCGTGCAG GAATCCAACTGAATCGACGTTCTCGCCCCGCAACCGACGTCATAGAGGTCACTCACGCCCGCTGCAACAACCTGGGTGAT GTGTCTGTGAGCTTTCCGGTCGGGGCACTCACGGTCGTATCTGGGGTGGCGGGTTCCGGAAAGAGTTCGCTGGCATCTGC TTTGGCCCAGCAGCACCCGGAAGTCACCATCATCGATCAATTGCCACTAGCAGCATCCAGCCGCTCCTCCATATTGACTG CTCTGGGTCTTGAATCCCCAATCCGCGAAGCCTTTTCCAAAATCTCAGGTTTGACTACCAGCTGGTTCAGCGCGAATGAG AAAGGCGCGTGCCCCTTGTGCAAGGGACGCGGCACGACACACGTAGACATGGCCTTCATGGATGACGTCCAAACACCGTG TGAGCGCTGCGGCGGCAGGAAGTTCAACGAAACCACGATGGCAGTCCGACTCCCAATGGGCTCGCTTAACCCCACGATCG CGGATGTTCTTGACAGCGGTTTGAATCAGGTCAGCGAACTATACGCCACCCAGGATGACGTGCTCACCGTCATATCCTTG CTCCAGCAGGTTGGCCTCGGCTATCTCACCTTGGGACGGACACTAAACACGCTCTCTGGCGGTGAGCTCCAGCGGATAAA GCTCGTCCAGTTCCTCAAGGAACATCGGGAGGAACAGGAAAGCGTGCTCGTATTAGATGAGATTACGACCGGATTACATC CCAAAGATGTAGAGCAATTGATCCAATTTTTACGCCGATTGTCCGAGAGGGGTGCAACCGCCATCGCGATCGACCATAAC CCAGGGCTCATCTCTCAGGCCGATTACAACATCGATCTCGGCCCAGGCGCGGAGGCTGCAGGAGGCACAGTAGTCTTCTC CGGAACGGCGCAGGGACTGGCTGACTGTCCGGAGTCCACGACAGGCAAATGGCTTCACAAATTGAACTGCTCATCCTCCG GCGTTGAACAAGTGCCATGA
Upstream 100 bases:
>100_bases GAAACGGCGATTAGGTCGATGACGAAGGATGAGCTGGAGGTATTTGCTCGCTTGTCTGAAAAGCTGTCTTCTTCCCTCAA GCAGCAACGGATTGCGAGCC
Downstream 100 bases:
>100_bases GCATTTCTTATGTTGGCAGACAAGAAACGGTAGGAGGCCAGCTTGCCGAGTAGCCAGCGTTTGTAGCTGCTTTAGGGTAA AGAAAATACCCGTCACCGTG
Product: UvrA-like ABC transporter
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 779; Mature: 779
Protein sequence:
>779_residues MRNLRKDIVSRSSVGSIQIHGAKTHNLRDVTVCIPKHALVGVAGVSGSGKTSLVSTLAVGAQQAVSSLFPAFVQARLNTL EPGLVDGLQGLTFTAIVGQKKFSRNARSSVSTASGIAPYLRLLFSRSGSPSAGYSPSYSPNDPRGMCMDCSGLGYVDDID LQELIAPDRSLNEGAVRFPSFEPGTYRWKRLVCSGLFDPDVPWKELPEASRKLLLHGQGVRLERPLTGYPKHGIFDGIIP RLKASYLEKANAKTTEKEDAALRRIVKRVVCPHCHGQRINEAARASRIEGLNIAEASHLSIDECIAFIKTITDEITEAPR QAVLARLNNMRDIGLGYLSLDRPTDTLSGGEAQRLRLVSLLDAPITDATFVMDEPSSGLHPADIERLLRSLRKLRDSGNT VIIVEHNLQVLAACDHVVELGPGAGDDGGRVLFEGSPRSLTRSDTPTGKALRAGIQLNRRSRPATDVIEVTHARCNNLGD VSVSFPVGALTVVSGVAGSGKSSLASALAQQHPEVTIIDQLPLAASSRSSILTALGLESPIREAFSKISGLTTSWFSANE KGACPLCKGRGTTHVDMAFMDDVQTPCERCGGRKFNETTMAVRLPMGSLNPTIADVLDSGLNQVSELYATQDDVLTVISL LQQVGLGYLTLGRTLNTLSGGELQRIKLVQFLKEHREEQESVLVLDEITTGLHPKDVEQLIQFLRRLSERGATAIAIDHN PGLISQADYNIDLGPGAEAAGGTVVFSGTAQGLADCPESTTGKWLHKLNCSSSGVEQVP
Sequences:
>Translated_779_residues MRNLRKDIVSRSSVGSIQIHGAKTHNLRDVTVCIPKHALVGVAGVSGSGKTSLVSTLAVGAQQAVSSLFPAFVQARLNTL EPGLVDGLQGLTFTAIVGQKKFSRNARSSVSTASGIAPYLRLLFSRSGSPSAGYSPSYSPNDPRGMCMDCSGLGYVDDID LQELIAPDRSLNEGAVRFPSFEPGTYRWKRLVCSGLFDPDVPWKELPEASRKLLLHGQGVRLERPLTGYPKHGIFDGIIP RLKASYLEKANAKTTEKEDAALRRIVKRVVCPHCHGQRINEAARASRIEGLNIAEASHLSIDECIAFIKTITDEITEAPR QAVLARLNNMRDIGLGYLSLDRPTDTLSGGEAQRLRLVSLLDAPITDATFVMDEPSSGLHPADIERLLRSLRKLRDSGNT VIIVEHNLQVLAACDHVVELGPGAGDDGGRVLFEGSPRSLTRSDTPTGKALRAGIQLNRRSRPATDVIEVTHARCNNLGD VSVSFPVGALTVVSGVAGSGKSSLASALAQQHPEVTIIDQLPLAASSRSSILTALGLESPIREAFSKISGLTTSWFSANE KGACPLCKGRGTTHVDMAFMDDVQTPCERCGGRKFNETTMAVRLPMGSLNPTIADVLDSGLNQVSELYATQDDVLTVISL LQQVGLGYLTLGRTLNTLSGGELQRIKLVQFLKEHREEQESVLVLDEITTGLHPKDVEQLIQFLRRLSERGATAIAIDHN PGLISQADYNIDLGPGAEAAGGTVVFSGTAQGLADCPESTTGKWLHKLNCSSSGVEQVP >Mature_779_residues MRNLRKDIVSRSSVGSIQIHGAKTHNLRDVTVCIPKHALVGVAGVSGSGKTSLVSTLAVGAQQAVSSLFPAFVQARLNTL EPGLVDGLQGLTFTAIVGQKKFSRNARSSVSTASGIAPYLRLLFSRSGSPSAGYSPSYSPNDPRGMCMDCSGLGYVDDID LQELIAPDRSLNEGAVRFPSFEPGTYRWKRLVCSGLFDPDVPWKELPEASRKLLLHGQGVRLERPLTGYPKHGIFDGIIP RLKASYLEKANAKTTEKEDAALRRIVKRVVCPHCHGQRINEAARASRIEGLNIAEASHLSIDECIAFIKTITDEITEAPR QAVLARLNNMRDIGLGYLSLDRPTDTLSGGEAQRLRLVSLLDAPITDATFVMDEPSSGLHPADIERLLRSLRKLRDSGNT VIIVEHNLQVLAACDHVVELGPGAGDDGGRVLFEGSPRSLTRSDTPTGKALRAGIQLNRRSRPATDVIEVTHARCNNLGD VSVSFPVGALTVVSGVAGSGKSSLASALAQQHPEVTIIDQLPLAASSRSSILTALGLESPIREAFSKISGLTTSWFSANE KGACPLCKGRGTTHVDMAFMDDVQTPCERCGGRKFNETTMAVRLPMGSLNPTIADVLDSGLNQVSELYATQDDVLTVISL LQQVGLGYLTLGRTLNTLSGGELQRIKLVQFLKEHREEQESVLVLDEITTGLHPKDVEQLIQFLRRLSERGATAIAIDHN PGLISQADYNIDLGPGAEAAGGTVVFSGTAQGLADCPESTTGKWLHKLNCSSSGVEQVP
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=709, Percent_Identity=34.132581100141, Blast_Score=355, Evalue=7e-99,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 83498; Mature: 83498
Theoretical pI: Translated: 7.24; Mature: 7.24
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRNLRKDIVSRSSVGSIQIHGAKTHNLRDVTVCIPKHALVGVAGVSGSGKTSLVSTLAVG CCCHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCHHHEEEECCCCCCHHHHHHHHHHH AQQAVSSLFPAFVQARLNTLEPGLVDGLQGLTFTAIVGQKKFSRNARSSVSTASGIAPYL HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHH RLLFSRSGSPSAGYSPSYSPNDPRGMCMDCSGLGYVDDIDLQELIAPDRSLNEGAVRFPS HHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHCCCCCCCCCCEECCC FEPGTYRWKRLVCSGLFDPDVPWKELPEASRKLLLHGQGVRLERPLTGYPKHGIFDGIIP CCCCHHHHHHHHHHCCCCCCCCHHHCCHHHHHEEEECCCCEECCCCCCCCCCCCHHHHHH RLKASYLEKANAKTTEKEDAALRRIVKRVVCPHCHGQRINEAARASRIEGLNIAEASHLS HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC IDECIAFIKTITDEITEAPRQAVLARLNNMRDIGLGYLSLDRPTDTLSGGEAQRLRLVSL HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEECCCCCCCCCCCCHHHHHHHHH LDAPITDATFVMDEPSSGLHPADIERLLRSLRKLRDSGNTVIIVEHNLQVLAACDHVVEL HCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHC GPGAGDDGGRVLFEGSPRSLTRSDTPTGKALRAGIQLNRRSRPATDVIEVTHARCNNLGD CCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCC VSVSFPVGALTVVSGVAGSGKSSLASALAQQHPEVTIIDQLPLAASSRSSILTALGLESP EEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHCCCHH IREAFSKISGLTTSWFSANEKGACPLCKGRGTTHVDMAFMDDVQTPCERCGGRKFNETTM HHHHHHHHHCCEEHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEE AVRLPMGSLNPTIADVLDSGLNQVSELYATQDDVLTVISLLQQVGLGYLTLGRTLNTLSG EEEECCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEECCCHHHCCCC GELQRIKLVQFLKEHREEQESVLVLDEITTGLHPKDVEQLIQFLRRLSERGATAIAIDHN CCHHHHHHHHHHHHHHHHHHHEEEEHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC PGLISQADYNIDLGPGAEAAGGTVVFSGTAQGLADCPESTTGKWLHKLNCSSSGVEQVP CCCCCCCCCCEECCCCCCCCCCEEEECCCCCHHHCCCCCCCHHHHHHCCCCCCCCCCCC >Mature Secondary Structure MRNLRKDIVSRSSVGSIQIHGAKTHNLRDVTVCIPKHALVGVAGVSGSGKTSLVSTLAVG CCCHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCHHHEEEECCCCCCHHHHHHHHHHH AQQAVSSLFPAFVQARLNTLEPGLVDGLQGLTFTAIVGQKKFSRNARSSVSTASGIAPYL HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHH RLLFSRSGSPSAGYSPSYSPNDPRGMCMDCSGLGYVDDIDLQELIAPDRSLNEGAVRFPS HHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHCCCCCCCCCCEECCC FEPGTYRWKRLVCSGLFDPDVPWKELPEASRKLLLHGQGVRLERPLTGYPKHGIFDGIIP CCCCHHHHHHHHHHCCCCCCCCHHHCCHHHHHEEEECCCCEECCCCCCCCCCCCHHHHHH RLKASYLEKANAKTTEKEDAALRRIVKRVVCPHCHGQRINEAARASRIEGLNIAEASHLS HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC IDECIAFIKTITDEITEAPRQAVLARLNNMRDIGLGYLSLDRPTDTLSGGEAQRLRLVSL HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEECCCCCCCCCCCCHHHHHHHHH LDAPITDATFVMDEPSSGLHPADIERLLRSLRKLRDSGNTVIIVEHNLQVLAACDHVVEL HCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHC GPGAGDDGGRVLFEGSPRSLTRSDTPTGKALRAGIQLNRRSRPATDVIEVTHARCNNLGD CCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCC VSVSFPVGALTVVSGVAGSGKSSLASALAQQHPEVTIIDQLPLAASSRSSILTALGLESP EEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHCCCHH IREAFSKISGLTTSWFSANEKGACPLCKGRGTTHVDMAFMDDVQTPCERCGGRKFNETTM HHHHHHHHHCCEEHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEE AVRLPMGSLNPTIADVLDSGLNQVSELYATQDDVLTVISLLQQVGLGYLTLGRTLNTLSG EEEECCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEECCCHHHCCCC GELQRIKLVQFLKEHREEQESVLVLDEITTGLHPKDVEQLIQFLRRLSERGATAIAIDHN CCHHHHHHHHHHHHHHHHHHHEEEEHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC PGLISQADYNIDLGPGAEAAGGTVVFSGTAQGLADCPESTTGKWLHKLNCSSSGVEQVP CCCCCCCCCCEECCCCCCCCCCEEEECCCCCHHHCCCCCCCHHHHHHCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA