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The map label for this gene is coaE

Identifier: 50842272

GI number: 50842272

Start: 864204

End: 864899

Strand: Direct

Name: coaE

Synonym: PPA0785

Alternate gene names: 50842272

Gene position: 864204-864899 (Clockwise)

Preceding gene: 50842271

Following gene: 50842273

Centisome position: 33.75

GC content: 60.63

Gene sequence:

>696_bases
GTGAGGCGCACGGTGATAGGTGATGAGACGACAGCGCGGGATGTTGCGCGAGCTGATTGGGTCGCAGGGGCCGGTGGTGT
TGTTCGGGTGGGTCTGACTGGTGGTATTGCCAGTGGTAAGTCGACGGTGTCGCAGATGCTGGGTGAGCGTGGAGCTGTCA
TTATCGATTATGACCGGCTCTCCCGGGATGTCGTTGCGGTGGGGACGCAGGGGCTTGCTCAGGTCGTTGAGGCCTTTGGG
CGTGAGGTTCTTGTTGCTGATGGTTCTCTTAATCGATCGGCTCTGGGGTCGATCGTGTTTGCTGATTTGCAGGCGCGCCG
CCGTCTTGAAGCCATTATTCATCCGCTGGTAGAAGAAGCTGCCCACCGGGTCGACGAGGAAGCCCGGGCTGCCGACGGAC
TCGTGGTCGTTGTCCATGACATCCCGCTGCTCGTCGAAACTGGGCGTGCCGACGAGTTCGATGTCGTGATGGTGACCGAC
GTCGATCCGGCTGAGCAGGTACGTCGGGTTGTCGAGAGGGATGGGTGCAGTCAGGCCGATGCGTGGGCGAGGATTCACGC
TCAGGCTTCTCGTGAGGAGCATCTGGCGGTTGCCGATGTCATTATCGATACCAGCGTTCCGCTGGAGGATCTGCCCGAGC
AGATCGATCGGGTGTGGTCACGGATTGCGGGAGCTCTCCGCTTTGATCGGCGATGA

Upstream 100 bases:

>100_bases
CATGAATGCGATTGTGGTGGTGAGACTGTTGTGTTGGATCGTGGCAGGGTTGTGAAGCATCTGCGTCGATAATTGGCAGG
GTGCCCGGGGGAGACGGGAT

Downstream 100 bases:

>100_bases
GGAAAAATGTGACTATTGTTTGTCGGGTGACTTTTACGAGGGTTATGCGGTAGCGAAGGCGGACAAAGAACATCTATATG
TTCCATGAACATGTGCGGTA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MRRTVIGDETTARDVARADWVAGAGGVVRVGLTGGIASGKSTVSQMLGERGAVIIDYDRLSRDVVAVGTQGLAQVVEAFG
REVLVADGSLNRSALGSIVFADLQARRRLEAIIHPLVEEAAHRVDEEARAADGLVVVVHDIPLLVETGRADEFDVVMVTD
VDPAEQVRRVVERDGCSQADAWARIHAQASREEHLAVADVIIDTSVPLEDLPEQIDRVWSRIAGALRFDRR

Sequences:

>Translated_231_residues
MRRTVIGDETTARDVARADWVAGAGGVVRVGLTGGIASGKSTVSQMLGERGAVIIDYDRLSRDVVAVGTQGLAQVVEAFG
REVLVADGSLNRSALGSIVFADLQARRRLEAIIHPLVEEAAHRVDEEARAADGLVVVVHDIPLLVETGRADEFDVVMVTD
VDPAEQVRRVVERDGCSQADAWARIHAQASREEHLAVADVIIDTSVPLEDLPEQIDRVWSRIAGALRFDRR
>Mature_231_residues
MRRTVIGDETTARDVARADWVAGAGGVVRVGLTGGIASGKSTVSQMLGERGAVIIDYDRLSRDVVAVGTQGLAQVVEAFG
REVLVADGSLNRSALGSIVFADLQARRRLEAIIHPLVEEAAHRVDEEARAADGLVVVVHDIPLLVETGRADEFDVVMVTD
VDPAEQVRRVVERDGCSQADAWARIHAQASREEHLAVADVIIDTSVPLEDLPEQIDRVWSRIAGALRFDRR

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=179, Percent_Identity=37.4301675977654, Blast_Score=107, Evalue=7e-24,
Organism=Homo sapiens, GI191252795, Length=179, Percent_Identity=37.4301675977654, Blast_Score=107, Evalue=7e-24,
Organism=Homo sapiens, GI110227607, Length=191, Percent_Identity=35.0785340314136, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI110227605, Length=193, Percent_Identity=34.7150259067358, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI110227603, Length=193, Percent_Identity=34.7150259067358, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI110227601, Length=193, Percent_Identity=34.7150259067358, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI205277394, Length=193, Percent_Identity=34.7150259067358, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1786292, Length=176, Percent_Identity=38.0681818181818, Blast_Score=111, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17554944, Length=202, Percent_Identity=35.1485148514851, Blast_Score=111, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25143409, Length=195, Percent_Identity=32.3076923076923, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320402, Length=202, Percent_Identity=39.1089108910891, Blast_Score=104, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24658602, Length=198, Percent_Identity=34.8484848484849, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24644728, Length=183, Percent_Identity=32.7868852459016, Blast_Score=101, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_PROAC (Q6A9M5)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_055499.1
- ProteinModelPortal:   Q6A9M5
- SMR:   Q6A9M5
- GeneID:   2931092
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA0785
- NMPDR:   fig|267747.1.peg.776
- HOGENOM:   HBG650290
- OMA:   IIAREVV
- ProtClustDB:   CLSK2763529
- BioCyc:   PACN267747:PPA0785-MONOMER
- BRENDA:   2.7.1.24
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 24972; Mature: 24972

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS51219 DPCK; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTVIGDETTARDVARADWVAGAGGVVRVGLTGGIASGKSTVSQMLGERGAVIIDYDRL
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEHHHH
SRDVVAVGTQGLAQVVEAFGREVLVADGSLNRSALGSIVFADLQARRRLEAIIHPLVEEA
CCHHHHHCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHRVDEEARAADGLVVVVHDIPLLVETGRADEFDVVMVTDVDPAEQVRRVVERDGCSQAD
HHHHCHHHHHCCCEEEEEECCCEEEECCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCHH
AWARIHAQASREEHLAVADVIIDTSVPLEDLPEQIDRVWSRIAGALRFDRR
HHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRRTVIGDETTARDVARADWVAGAGGVVRVGLTGGIASGKSTVSQMLGERGAVIIDYDRL
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEHHHH
SRDVVAVGTQGLAQVVEAFGREVLVADGSLNRSALGSIVFADLQARRRLEAIIHPLVEEA
CCHHHHHCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHRVDEEARAADGLVVVVHDIPLLVETGRADEFDVVMVTDVDPAEQVRRVVERDGCSQAD
HHHHCHHHHHCCCEEEEEECCCEEEECCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCHH
AWARIHAQASREEHLAVADVIIDTSVPLEDLPEQIDRVWSRIAGALRFDRR
HHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA