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The map label for this gene is helD [H]

Identifier: 50842221

GI number: 50842221

Start: 804584

End: 806845

Strand: Reverse

Name: helD [H]

Synonym: PPA0733

Alternate gene names: 50842221

Gene position: 806845-804584 (Counterclockwise)

Preceding gene: 50842222

Following gene: 50842220

Centisome position: 31.51

GC content: 62.78

Gene sequence:

>2262_bases
TTGACCGCACACGATAGTTCGACCACCGACCCCCGCGTTGTGGAAACTGAGATCGCCAAGGAACAGGACCACGTCGACCG
CGTCCGCGCCCAATTGGAGATCGACGAGAACAAAGCCCGCATGCTAGCCAAGGCCGGCCAAGACATGTACCGCTCGGACC
GCACCAGTTGGGTTCGTGAAGAGGACGGCACGGCGATGTTTGAACGCGACGCCTTCTCTTATAACGCGGCAAAGAGATTA
GCGGTCCTTGACGCTGAGCATGAAGGTCTGGTCTTCGGCCGACTTGATCTGGCTGACGACGAGGTGCGTCACATCGGGAG
AATCGGGGTACGGGACGCCGACTATGAGCCTCTCGTCATCGACTGGCGTGCCCGCGCTGCCGAGCCCTTTTACCGAGCCA
CCCCGTCTGATCCGATGGGTGTTGTTCGTCGCCGCGTCTTGCGCTGTCGCGATGACAAGGTCCTCGGCATCGAAGATGAC
CTGCTGGATTCCACCTCGCAGGCGAATCTGCCGATTATCGGCGAGGGAGCCCTCATGGCGTCTCTCTCTCGGGCCCGCGA
CACTCGAATGCATTCAATCGTCTCGACGATCCAGGCCGAGCAGGATGAGGCCATTCGCGCCCCTTACCAAGGCGTAACGA
CGATTATGGGCGGACCTGGCACCGGCAAGACGGTCGTCGCTCTGCACCGCGCAGCATTCCTGCTTTATTCTCATCGCACT
CGGCTGGAGAATGGCGGGGTGCTCGTCATCGGGCCGTCACCGGTTTTCATGAGCTACATCGAGCGGGTGCTACCCAGCCT
CGGGGAAGACTCCGTAACACTGCGCTCAGTAGGCCAGGTGCCGTCGGATATCCTGCGCTTCTCCTCTGACCGTCTCGATG
AGCCCCGTACTGCCAATATCAAGGGCAGCCTTGAGATGGTTGACGTGCTCACCCGACTGGTCAATTTGCCCATGTCGGCG
GATCCCGATTCCTTGCAGCTGCGAGTAACGGTCAAAGGCGAGGTTCTTACCCTCGATGCCTCCATCCTCGCGACGACCCG
TCAACGCATCCTCAAGCGCAATCGCTACAACGACGGCAGGGAGGCCGTTGAGGTCTCGCTGCGCGACCAGCTGTGGGCAA
GAGTCCCGGCCGATGTCCTCGCCGCCCATGACCTCACAAGGGACGATTTCGACGAGCTAGTGTCCTCCCAGGCATCCTGG
CGGATGCTCCTCAACGCCTGGTGGCCCGCCCTGTCGGCCTCCGACGCCCTCGCTCGGTTGGCCGATCCCGCGGTCGCCGA
AGCAGTGACCCCCGACTGGAACGAGGAAACCCGTCAGCTTCTCGTCAGCTCTATCCCGACCGAAGCGGATCGACGTGGAC
GGCGCAACTGGTCGATAGCCGATATGGCCCTGCTCGACGAGTTGGCCGCTCTGCTCGGCCCAGTTCCCCCCGAGCCCGAT
GCCGACGACCCGGTCTTTATCGAGGGAGGTGACGCCGAGGAACTCGTCACCCTCGGCGATCGTCTCCATGAGTCCCGCCA
CATTGACGAGGACGAGCCTCGCGATACCTTCGCTCACGTTCTCGTCGACGAGGCCCAAGACATCTCCCCCATGCAGTGGC
GGATGATCGGACGTCGAGGCCGCCAGGCTTCCTGGACGATCGTCGGGGACCCGGCCCAGTCTGCCTTCCCCCATCCCGAC
CAGACCAGAGCGGCCTTGGACGAATTGGTTGGTAATTCCCCGTCACGCACCTTCACCCTGACCAAGAACTACCGTTCCCC
GGCCGAGGTTTTCGATATCGCCGCCGACGTGGTTGTCACCGTCCAGCCCGACGCTGATCTTCCACAGGCGGTGCGCTGGG
TTGGTGTCCGTCCCACGGTGGTACGCACTGACGACCTATGGGCACAGGTGCGCTCGCAGCTGGACGAGATGCTCACATCG
GTGGACGGGACGATCGGTCTGGTGTGCCCGGCTGGCCTCTTCGAGCAGGCGCGCCGGCTTGCCGATGATCCTCGCATCAT
CACGGTGACGACCATGCAGGCCAAGGGTCTTGAGTACGATGGTGCAGTAGTCGTCGATCCCGAGCGCATCGTCTCCGAGA
CCGGTAATCCTGCCGGTGGCGTCCGGTTGCTCTACGTCGCTTTGACCCGCCCTACCCAACGGTTAGCGGTAGTCGGGCTC
AGGAAGCAGAAATCGCCTCATCGTTCCGAGGCGAACCAGCCCGTTCGAGGCGCCGCCGCGCCAGCATGGTCCGAAGCTCT
GTGGTCGCACGAGACCTGTTGA

Upstream 100 bases:

>100_bases
AGAAGAAGTCACAGTTCCACTGACAGGGTCTCGACGCGTAGACTTGACCGTTAGCCCCACGGCACCGCGCCTGGAGGCAA
ACATCTCGTGAAGGACGACT

Downstream 100 bases:

>100_bases
GGGTGTAGTGGTGGAAGCCGAGAGCGCCAACATTAAAGAGCTCACAGCCCATGTCACGCACCCTCTCTACCGATGCATGT
CTCTGGGTGAACCCGCTTAA

Product: putative helicase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 753; Mature: 752

Protein sequence:

>753_residues
MTAHDSSTTDPRVVETEIAKEQDHVDRVRAQLEIDENKARMLAKAGQDMYRSDRTSWVREEDGTAMFERDAFSYNAAKRL
AVLDAEHEGLVFGRLDLADDEVRHIGRIGVRDADYEPLVIDWRARAAEPFYRATPSDPMGVVRRRVLRCRDDKVLGIEDD
LLDSTSQANLPIIGEGALMASLSRARDTRMHSIVSTIQAEQDEAIRAPYQGVTTIMGGPGTGKTVVALHRAAFLLYSHRT
RLENGGVLVIGPSPVFMSYIERVLPSLGEDSVTLRSVGQVPSDILRFSSDRLDEPRTANIKGSLEMVDVLTRLVNLPMSA
DPDSLQLRVTVKGEVLTLDASILATTRQRILKRNRYNDGREAVEVSLRDQLWARVPADVLAAHDLTRDDFDELVSSQASW
RMLLNAWWPALSASDALARLADPAVAEAVTPDWNEETRQLLVSSIPTEADRRGRRNWSIADMALLDELAALLGPVPPEPD
ADDPVFIEGGDAEELVTLGDRLHESRHIDEDEPRDTFAHVLVDEAQDISPMQWRMIGRRGRQASWTIVGDPAQSAFPHPD
QTRAALDELVGNSPSRTFTLTKNYRSPAEVFDIAADVVVTVQPDADLPQAVRWVGVRPTVVRTDDLWAQVRSQLDEMLTS
VDGTIGLVCPAGLFEQARRLADDPRIITVTTMQAKGLEYDGAVVVDPERIVSETGNPAGGVRLLYVALTRPTQRLAVVGL
RKQKSPHRSEANQPVRGAAAPAWSEALWSHETC

Sequences:

>Translated_753_residues
MTAHDSSTTDPRVVETEIAKEQDHVDRVRAQLEIDENKARMLAKAGQDMYRSDRTSWVREEDGTAMFERDAFSYNAAKRL
AVLDAEHEGLVFGRLDLADDEVRHIGRIGVRDADYEPLVIDWRARAAEPFYRATPSDPMGVVRRRVLRCRDDKVLGIEDD
LLDSTSQANLPIIGEGALMASLSRARDTRMHSIVSTIQAEQDEAIRAPYQGVTTIMGGPGTGKTVVALHRAAFLLYSHRT
RLENGGVLVIGPSPVFMSYIERVLPSLGEDSVTLRSVGQVPSDILRFSSDRLDEPRTANIKGSLEMVDVLTRLVNLPMSA
DPDSLQLRVTVKGEVLTLDASILATTRQRILKRNRYNDGREAVEVSLRDQLWARVPADVLAAHDLTRDDFDELVSSQASW
RMLLNAWWPALSASDALARLADPAVAEAVTPDWNEETRQLLVSSIPTEADRRGRRNWSIADMALLDELAALLGPVPPEPD
ADDPVFIEGGDAEELVTLGDRLHESRHIDEDEPRDTFAHVLVDEAQDISPMQWRMIGRRGRQASWTIVGDPAQSAFPHPD
QTRAALDELVGNSPSRTFTLTKNYRSPAEVFDIAADVVVTVQPDADLPQAVRWVGVRPTVVRTDDLWAQVRSQLDEMLTS
VDGTIGLVCPAGLFEQARRLADDPRIITVTTMQAKGLEYDGAVVVDPERIVSETGNPAGGVRLLYVALTRPTQRLAVVGL
RKQKSPHRSEANQPVRGAAAPAWSEALWSHETC
>Mature_752_residues
TAHDSSTTDPRVVETEIAKEQDHVDRVRAQLEIDENKARMLAKAGQDMYRSDRTSWVREEDGTAMFERDAFSYNAAKRLA
VLDAEHEGLVFGRLDLADDEVRHIGRIGVRDADYEPLVIDWRARAAEPFYRATPSDPMGVVRRRVLRCRDDKVLGIEDDL
LDSTSQANLPIIGEGALMASLSRARDTRMHSIVSTIQAEQDEAIRAPYQGVTTIMGGPGTGKTVVALHRAAFLLYSHRTR
LENGGVLVIGPSPVFMSYIERVLPSLGEDSVTLRSVGQVPSDILRFSSDRLDEPRTANIKGSLEMVDVLTRLVNLPMSAD
PDSLQLRVTVKGEVLTLDASILATTRQRILKRNRYNDGREAVEVSLRDQLWARVPADVLAAHDLTRDDFDELVSSQASWR
MLLNAWWPALSASDALARLADPAVAEAVTPDWNEETRQLLVSSIPTEADRRGRRNWSIADMALLDELAALLGPVPPEPDA
DDPVFIEGGDAEELVTLGDRLHESRHIDEDEPRDTFAHVLVDEAQDISPMQWRMIGRRGRQASWTIVGDPAQSAFPHPDQ
TRAALDELVGNSPSRTFTLTKNYRSPAEVFDIAADVVVTVQPDADLPQAVRWVGVRPTVVRTDDLWAQVRSQLDEMLTSV
DGTIGLVCPAGLFEQARRLADDPRIITVTTMQAKGLEYDGAVVVDPERIVSETGNPAGGVRLLYVALTRPTQRLAVVGLR
KQKSPHRSEANQPVRGAAAPAWSEALWSHETC

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 83331; Mature: 83200

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAHDSSTTDPRVVETEIAKEQDHVDRVRAQLEIDENKARMLAKAGQDMYRSDRTSWVRE
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHCCCCCHHCC
EDGTAMFERDAFSYNAAKRLAVLDAEHEGLVFGRLDLADDEVRHIGRIGVRDADYEPLVI
CCCCEEEECCCCCCCHHHEEEEEECCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCEEE
DWRARAAEPFYRATPSDPMGVVRRRVLRCRDDKVLGIEDDLLDSTSQANLPIIGEGALMA
ECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCHHHHCCCCCCCCCEEECCHHHH
SLSRARDTRMHSIVSTIQAEQDEAIRAPYQGVTTIMGGPGTGKTVVALHRAAFLLYSHRT
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
RLENGGVLVIGPSPVFMSYIERVLPSLGEDSVTLRSVGQVPSDILRFSSDRLDEPRTANI
EECCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHCHHCCCCCCCCCC
KGSLEMVDVLTRLVNLPMSADPDSLQLRVTVKGEVLTLDASILATTRQRILKRNRYNDGR
CCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCEEEEECHHHHHHHHHHHHHHCCCCCCH
EAVEVSLRDQLWARVPADVLAAHDLTRDDFDELVSSQASWRMLLNAWWPALSASDALARL
HHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHH
ADPAVAEAVTPDWNEETRQLLVSSIPTEADRRGRRNWSIADMALLDELAALLGPVPPEPD
CCHHHHHHCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
ADDPVFIEGGDAEELVTLGDRLHESRHIDEDEPRDTFAHVLVDEAQDISPMQWRMIGRRG
CCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCC
RQASWTIVGDPAQSAFPHPDQTRAALDELVGNSPSRTFTLTKNYRSPAEVFDIAADVVVT
CCEEEEEEECCHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCEEEE
VQPDADLPQAVRWVGVRPTVVRTDDLWAQVRSQLDEMLTSVDGTIGLVCPAGLFEQARRL
ECCCCCCHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHH
ADDPRIITVTTMQAKGLEYDGAVVVDPERIVSETGNPAGGVRLLYVALTRPTQRLAVVGL
CCCCCEEEEEEEEECCCCCCCEEEECHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHH
RKQKSPHRSEANQPVRGAAAPAWSEALWSHETC
HHCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
TAHDSSTTDPRVVETEIAKEQDHVDRVRAQLEIDENKARMLAKAGQDMYRSDRTSWVRE
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHCCCCCHHCC
EDGTAMFERDAFSYNAAKRLAVLDAEHEGLVFGRLDLADDEVRHIGRIGVRDADYEPLVI
CCCCEEEECCCCCCCHHHEEEEEECCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCEEE
DWRARAAEPFYRATPSDPMGVVRRRVLRCRDDKVLGIEDDLLDSTSQANLPIIGEGALMA
ECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCHHHHCCCCCCCCCEEECCHHHH
SLSRARDTRMHSIVSTIQAEQDEAIRAPYQGVTTIMGGPGTGKTVVALHRAAFLLYSHRT
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
RLENGGVLVIGPSPVFMSYIERVLPSLGEDSVTLRSVGQVPSDILRFSSDRLDEPRTANI
EECCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHCHHCCCCCCCCCC
KGSLEMVDVLTRLVNLPMSADPDSLQLRVTVKGEVLTLDASILATTRQRILKRNRYNDGR
CCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCEEEEECHHHHHHHHHHHHHHCCCCCCH
EAVEVSLRDQLWARVPADVLAAHDLTRDDFDELVSSQASWRMLLNAWWPALSASDALARL
HHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHH
ADPAVAEAVTPDWNEETRQLLVSSIPTEADRRGRRNWSIADMALLDELAALLGPVPPEPD
CCHHHHHHCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
ADDPVFIEGGDAEELVTLGDRLHESRHIDEDEPRDTFAHVLVDEAQDISPMQWRMIGRRG
CCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCC
RQASWTIVGDPAQSAFPHPDQTRAALDELVGNSPSRTFTLTKNYRSPAEVFDIAADVVVT
CCEEEEEEECCHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCEEEE
VQPDADLPQAVRWVGVRPTVVRTDDLWAQVRSQLDEMLTSVDGTIGLVCPAGLFEQARRL
ECCCCCCHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHH
ADDPRIITVTTMQAKGLEYDGAVVVDPERIVSETGNPAGGVRLLYVALTRPTQRLAVVGL
CCCCCEEEEEEEEECCCCCCCEEEECHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHH
RKQKSPHRSEANQPVRGAAAPAWSEALWSHETC
HHCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]