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The map label for this gene is idsA [H]

Identifier: 50842220

GI number: 50842220

Start: 802887

End: 803984

Strand: Reverse

Name: idsA [H]

Synonym: PPA0732

Alternate gene names: 50842220

Gene position: 803984-802887 (Counterclockwise)

Preceding gene: 50842221

Following gene: 50842217

Centisome position: 31.4

GC content: 63.11

Gene sequence:

>1098_bases
ATGTACCCCTTTGATCCGTCCTCTCCAGTCAGCGCTGACTTCCGCGACTCCGTGAGCGCAAGGATCCTCTCCTTCCTCGA
CGACGAAAAGCGGGTCATTGACGCGATCGGCGCCGAGCTGTCCCCCGTTCTCGATGCCGCTCGTGATTACACCGCAGGCG
GCAAGCGATTGCGCCCGGCCTTCTGCTATTGGGGTCATGCAGCTGCGGCGGACCAACCCACTGAACCCGCCGGCCTGTTA
CAGGCGGCGGCGAGCCTCGAGTTTCTGCACGTGTCCGCCTTGGTCCACGACGACCTCATGGACCACTCCGACACCCGACG
TGGATTGCCTTCGGTGCACCGTCATTTCGAGGCGGCCCATGGCATTGCCCACGGAGACGGACCCGCTGAGCAATTCGGAT
TTGACATCGCGATCTTGCTCGGCGACCTGCTACTCATGTGGTCGTCGCAGATGTTCACGTCCGCCCCAGTCAAAGCTGAC
AGGCTGGCGGCCGCCACCCCGCTGCTTGACGCCATGCGCACCGAGGTCACCTGCGGCCAGGTCCTCGACGTCACCTCACA
GTCGGGAATGGCGGGGTCCGACTCCGAATCCGCTCTCGACCTGGTCGGCCGGGTTGTGGAGTACAAGTGCGCCTCATACA
CGGTCGTTCGTCCATGTCAGATTGGTGTGGCCTTGGCTGGGGGCTCTGACCGTCTACAACAGACGATGGCCGACTTCGGC
TCCCCCATCGGACGGGCCTTCCAATACCGCGACGATCTTCTTGGCGTCTTCGGCGACGCCGAGCTGACTGGCAAGCCCGC
TGGCGACGATCTGAGAGAAGGCAAGCGGACTGTGCTCGTCGCCCATGCGCTCAATCGGGCCGACTCCCACGACGCTGCTC
GCTTGAAGTCATTGCTGGGTCGCCCCGACCTCGACGATAACGACGTCGCCACCGCCCGTCGTATCATCGAGACAAGTGGA
GCCCGGGAGGCTGTCGAGTCAACAATTGTGCAGTGCCATGATCACGCCATCGCAGTTCTCGACGACGCCGAGATGACCGA
TGCCGGCCGAATTGCCCTGCGGGAATTAGCCCGCCAATGCGTCGAGCGTCATTTCTGA

Upstream 100 bases:

>100_bases
GACTACATAGGTGCGAGGCTAGGCGGCGCTCCCACCAGGTGGGCCAGACGTCCAGCGTACGGACTCGTTTCCGACCATCC
GACGCCTCTATGCTGGCGCT

Downstream 100 bases:

>100_bases
TACCACGATCCCGCGGCCTGAGTTTCACACCAGGAGGAGAGCGAAACCGTTGACCTCGTCCTCATCGAGACGCTGACCAA
TGACCTCAACTAGCCGACCC

Product: geranylgeranyl pyrophosphate synthase

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MYPFDPSSPVSADFRDSVSARILSFLDDEKRVIDAIGAELSPVLDAARDYTAGGKRLRPAFCYWGHAAAADQPTEPAGLL
QAAASLEFLHVSALVHDDLMDHSDTRRGLPSVHRHFEAAHGIAHGDGPAEQFGFDIAILLGDLLLMWSSQMFTSAPVKAD
RLAAATPLLDAMRTEVTCGQVLDVTSQSGMAGSDSESALDLVGRVVEYKCASYTVVRPCQIGVALAGGSDRLQQTMADFG
SPIGRAFQYRDDLLGVFGDAELTGKPAGDDLREGKRTVLVAHALNRADSHDAARLKSLLGRPDLDDNDVATARRIIETSG
AREAVESTIVQCHDHAIAVLDDAEMTDAGRIALRELARQCVERHF

Sequences:

>Translated_365_residues
MYPFDPSSPVSADFRDSVSARILSFLDDEKRVIDAIGAELSPVLDAARDYTAGGKRLRPAFCYWGHAAAADQPTEPAGLL
QAAASLEFLHVSALVHDDLMDHSDTRRGLPSVHRHFEAAHGIAHGDGPAEQFGFDIAILLGDLLLMWSSQMFTSAPVKAD
RLAAATPLLDAMRTEVTCGQVLDVTSQSGMAGSDSESALDLVGRVVEYKCASYTVVRPCQIGVALAGGSDRLQQTMADFG
SPIGRAFQYRDDLLGVFGDAELTGKPAGDDLREGKRTVLVAHALNRADSHDAARLKSLLGRPDLDDNDVATARRIIETSG
AREAVESTIVQCHDHAIAVLDDAEMTDAGRIALRELARQCVERHF
>Mature_365_residues
MYPFDPSSPVSADFRDSVSARILSFLDDEKRVIDAIGAELSPVLDAARDYTAGGKRLRPAFCYWGHAAAADQPTEPAGLL
QAAASLEFLHVSALVHDDLMDHSDTRRGLPSVHRHFEAAHGIAHGDGPAEQFGFDIAILLGDLLLMWSSQMFTSAPVKAD
RLAAATPLLDAMRTEVTCGQVLDVTSQSGMAGSDSESALDLVGRVVEYKCASYTVVRPCQIGVALAGGSDRLQQTMADFG
SPIGRAFQYRDDLLGVFGDAELTGKPAGDDLREGKRTVLVAHALNRADSHDAARLKSLLGRPDLDDNDVATARRIIETSG
AREAVESTIVQCHDHAIAVLDDAEMTDAGRIALRELARQCVERHF

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789578, Length=284, Percent_Identity=28.5211267605634, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786623, Length=333, Percent_Identity=28.8288288288288, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508563, Length=240, Percent_Identity=31.25, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17505681, Length=236, Percent_Identity=25.8474576271186, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 39220; Mature: 39220

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPFDPSSPVSADFRDSVSARILSFLDDEKRVIDAIGAELSPVLDAARDYTAGGKRLRPA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCH
FCYWGHAAAADQPTEPAGLLQAAASLEFLHVSALVHDDLMDHSDTRRGLPSVHRHFEAAH
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHC
GIAHGDGPAEQFGFDIAILLGDLLLMWSSQMFTSAPVKADRLAAATPLLDAMRTEVTCGQ
CCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
VLDVTSQSGMAGSDSESALDLVGRVVEYKCASYTVVRPCQIGVALAGGSDRLQQTMADFG
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEHHEEEEEEECCHHHHHHHHHHHC
SPIGRAFQYRDDLLGVFGDAELTGKPAGDDLREGKRTVLVAHALNRADSHDAARLKSLLG
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEEHHHHHCCCCCHHHHHHHHHHC
RPDLDDNDVATARRIIETSGAREAVESTIVQCHDHAIAVLDDAEMTDAGRIALRELARQC
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHH
VERHF
HHCCC
>Mature Secondary Structure
MYPFDPSSPVSADFRDSVSARILSFLDDEKRVIDAIGAELSPVLDAARDYTAGGKRLRPA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCH
FCYWGHAAAADQPTEPAGLLQAAASLEFLHVSALVHDDLMDHSDTRRGLPSVHRHFEAAH
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHC
GIAHGDGPAEQFGFDIAILLGDLLLMWSSQMFTSAPVKADRLAAATPLLDAMRTEVTCGQ
CCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
VLDVTSQSGMAGSDSESALDLVGRVVEYKCASYTVVRPCQIGVALAGGSDRLQQTMADFG
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEHHEEEEEEECCHHHHHHHHHHHC
SPIGRAFQYRDDLLGVFGDAELTGKPAGDDLREGKRTVLVAHALNRADSHDAARLKSLLG
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEEHHHHHCCCCCHHHHHHHHHHC
RPDLDDNDVATARRIIETSGAREAVESTIVQCHDHAIAVLDDAEMTDAGRIALRELARQC
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHH
VERHF
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]