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The map label for this gene is yvoA [H]

Identifier: 50842163

GI number: 50842163

Start: 744036

End: 744761

Strand: Direct

Name: yvoA [H]

Synonym: PPA0676

Alternate gene names: 50842163

Gene position: 744036-744761 (Clockwise)

Preceding gene: 50842161

Following gene: 50842164

Centisome position: 29.06

GC content: 60.06

Gene sequence:

>726_bases
ATGAAGTACGTGACCGTGCGGGATTACCTTGTCGAGCTCATCGACACCCGCTTATCGGTCGGGGATGTCGTGCCTAGTGA
GCGGGAGCTTGCTGAGCGGTTCGGTATCTCGCGCATGACGGTCCGCCAGGCGGTTGATTCGCTGGTGAGTAGCGGAATGC
TGGAGCGTCGTCGCGGCAGCGGTACCTATGTCAGAGCTCCCAAAGTGCATGTGCAGTCGCGCATCTCGTCTTTTAGTGAG
GAGATGCGTCAGCGCGGCATGATCCCAGACACCCGAGTGCTGCGCGATGAGGAGATCTCCGCCGCTCCTGACGTGGCTGT
GTGGCTAGGGATTGAGCCGGGGGAGCCAGTCCATTACATCTACCGCGTGCGGCTAGCTGACGGTGTTCCGATGGCCGTCG
AAAGGACCTGGATCGCTGCCCGAGTGATGCCAGATCTGTTGACCGATGGCGTTCCGGCGAGTATTTATGGGGCGATGGCG
GCAGCTGGGCTAGTTCCTACGTGGGGCGAGGATGCGATCGAGGCTGTCAGCGGTGACGCGCTGGTCTGCGAGCACCTGCA
GATCCCCGTCGGGTCGGCTGTATTGGCTATCAACCGTCGTACCTACGCCGACGATACCGCGATCTCTTATTCCCGATCTT
GGTACCGAGGGGATCGTTACAAACTATGGGTTCCGATCTCTGGTCCACACAGAACCCTGTATCCACCTCGAGGAGGTTCA
CGATGA

Upstream 100 bases:

>100_bases
GGCCATGTCAAGACAACGTGCAGAGTTTGTGAACGTCACCATGGTGGGGCTTTCGCGGTGATCGGTGCTGGTGGCACTGC
GCCCGAGGCATAATTCACCC

Downstream 100 bases:

>100_bases
AGCGTGTCGAGCACATCTTGGCGGCCTTGGGTGGAGTCGACAATGTCGTGTCGATCGAGCCATGCGTAACCCGGCTACGG
TGTCAGGTTCGTCGTTGCGA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MKYVTVRDYLVELIDTRLSVGDVVPSERELAERFGISRMTVRQAVDSLVSSGMLERRRGSGTYVRAPKVHVQSRISSFSE
EMRQRGMIPDTRVLRDEEISAAPDVAVWLGIEPGEPVHYIYRVRLADGVPMAVERTWIAARVMPDLLTDGVPASIYGAMA
AAGLVPTWGEDAIEAVSGDALVCEHLQIPVGSAVLAINRRTYADDTAISYSRSWYRGDRYKLWVPISGPHRTLYPPRGGS
R

Sequences:

>Translated_241_residues
MKYVTVRDYLVELIDTRLSVGDVVPSERELAERFGISRMTVRQAVDSLVSSGMLERRRGSGTYVRAPKVHVQSRISSFSE
EMRQRGMIPDTRVLRDEEISAAPDVAVWLGIEPGEPVHYIYRVRLADGVPMAVERTWIAARVMPDLLTDGVPASIYGAMA
AAGLVPTWGEDAIEAVSGDALVCEHLQIPVGSAVLAINRRTYADDTAISYSRSWYRGDRYKLWVPISGPHRTLYPPRGGS
R
>Mature_241_residues
MKYVTVRDYLVELIDTRLSVGDVVPSERELAERFGISRMTVRQAVDSLVSSGMLERRRGSGTYVRAPKVHVQSRISSFSE
EMRQRGMIPDTRVLRDEEISAAPDVAVWLGIEPGEPVHYIYRVRLADGVPMAVERTWIAARVMPDLLTDGVPASIYGAMA
AAGLVPTWGEDAIEAVSGDALVCEHLQIPVGSAVLAINRRTYADDTAISYSRSWYRGDRYKLWVPISGPHRTLYPPRGGS
R

Specific function: Acts as a weak repressor of yflG expression [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790118, Length=242, Percent_Identity=25.6198347107438, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1786950, Length=227, Percent_Identity=32.15859030837, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788418, Length=204, Percent_Identity=28.921568627451, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082252, Length=146, Percent_Identity=32.1917808219178, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1790540, Length=221, Percent_Identity=27.1493212669683, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 26774; Mature: 26774

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYVTVRDYLVELIDTRLSVGDVVPSERELAERFGISRMTVRQAVDSLVSSGMLERRRGS
CCEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
GTYVRAPKVHVQSRISSFSEEMRQRGMIPDTRVLRDEEISAAPDVAVWLGIEPGEPVHYI
CCEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEEEECCCCCCEEEE
YRVRLADGVPMAVERTWIAARVMPDLLTDGVPASIYGAMAAAGLVPTWGEDAIEAVSGDA
EEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCE
LVCEHLQIPVGSAVLAINRRTYADDTAISYSRSWYRGDRYKLWVPISGPHRTLYPPRGGS
EEEHHCCCCCCCEEEEECCCCCCCCCHHHHCHHHCCCCCEEEEEEECCCCCEECCCCCCC
R
C
>Mature Secondary Structure
MKYVTVRDYLVELIDTRLSVGDVVPSERELAERFGISRMTVRQAVDSLVSSGMLERRRGS
CCEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
GTYVRAPKVHVQSRISSFSEEMRQRGMIPDTRVLRDEEISAAPDVAVWLGIEPGEPVHYI
CCEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEEEECCCCCCEEEE
YRVRLADGVPMAVERTWIAARVMPDLLTDGVPASIYGAMAAAGLVPTWGEDAIEAVSGDA
EEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCE
LVCEHLQIPVGSAVLAINRRTYADDTAISYSRSWYRGDRYKLWVPISGPHRTLYPPRGGS
EEEHHCCCCCCCEEEEECCCCCCCCCHHHHCHHHCCCCCEEEEEEECCCCCEECCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]