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The map label for this gene is fecD [C]

Identifier: 50842144

GI number: 50842144

Start: 721409

End: 722443

Strand: Direct

Name: fecD [C]

Synonym: PPA0657

Alternate gene names: 50842144

Gene position: 721409-722443 (Clockwise)

Preceding gene: 50842143

Following gene: 50842145

Centisome position: 28.18

GC content: 62.71

Gene sequence:

>1035_bases
GTGAGCCGCTGGCGCAGTTGGCTCCTGCTCGGCATTGTCGTTGCTGCCCTGATCGGCAGTGCCCTCGTAGTCCTGGGGAT
CGGGGCAGTTCGGGTTCCGGTTTCCGATGTGGCGCGGGTGGTGGCGCGACGCTTTCGGCTCATTGAAGGAGCCGACGTGA
CGGTCCTCAACGACCAGATCGTATGGCAAATGAGGGCCCCGCGTGTCATCGGATCGATGGCCGTCGGTGCTTTGTTGGCG
ATGTGCGGCGCGGTGTTGCAGACCTTGACCGGCAACGATCTGGCTGATCCGTACCTACTAGGTATCTCCAGCGGGGCGTC
GGTCGGGGCGGTCTTCGTCCTGATCGTCGGGATTTCCAGCACCCTCGGGCAGTCGGTCCTTATGACCCTGGCCTCCTTCA
TTGGAGCCGTCGTAGCCTTGGTCATGGTGCTGACGATGGCCACGGGCAGATCAGGGGAATTGCCTGCCGGCCGAACAATC
TTGGCCGGTGTGGCCGTGGGCCAGTTGTGCGGAGCAGCGGTGTCGGTGATGATCATGATCTTCGGGGAGTCGAATGCGGC
CCGTTCAGCTCTGTCATGGACCCTTGGGTCCTTCGCCGGGCTGAGGTGGGGATCGACGATCACGCTGGTTGTTGCCACCG
TGCCGGCGCTGGTCGTCGGGATGGCTTTGTGCCACATCCTTGACGCCTTCGCATTTGGAGACATCAGTGCGATGTCGTTG
GGTGTTCCGGTGAACACTGTCCGCTGGGCAATCATGGTCAGCACGGCTCTGCTGACGGCCCTCAGCGTGGCGTTCGCTGG
ACCCATCGGCTTCGTCGGGCTCACGGTTCCCCATATCGTGAGATTCTGGACTGGGTCGCGTCACGCTCGTCTTCTGCCGA
TATCTGCCCTGGCCGGAGCGCTGCTCATGGTGTGGTCAGACACCGCTGCACGATGTTTACGTCCCGATACCGAAATCCCC
GTGGGCGTCATCACCGCGATCGTCGGGGCCCCGGTGCTAGTCGTGCTTTTGCGTCGACAGGCCTCGAGATCATGA

Upstream 100 bases:

>100_bases
ACAAATTCGTCACCGTGCCATTTTCCCAGACTACCCCTGGCGCCGAGCTGGTTGACGGAGCAAAGACTCTCAACGACGGC
CTGGCCAGGGTTACCGGGAA

Downstream 100 bases:

>100_bases
CAACGGTGACAACGTCAGCAGTGCTGAGGGCCGAGGCTCTTGGTTGGAGCGTGGATGGAAAGACGATCCTGTCAGGGGTC
AGTGTGGACGTTCGGCCTCA

Product: iron transport system, permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSRWRSWLLLGIVVAALIGSALVVLGIGAVRVPVSDVARVVARRFRLIEGADVTVLNDQIVWQMRAPRVIGSMAVGALLA
MCGAVLQTLTGNDLADPYLLGISSGASVGAVFVLIVGISSTLGQSVLMTLASFIGAVVALVMVLTMATGRSGELPAGRTI
LAGVAVGQLCGAAVSVMIMIFGESNAARSALSWTLGSFAGLRWGSTITLVVATVPALVVGMALCHILDAFAFGDISAMSL
GVPVNTVRWAIMVSTALLTALSVAFAGPIGFVGLTVPHIVRFWTGSRHARLLPISALAGALLMVWSDTAARCLRPDTEIP
VGVITAIVGAPVLVVLLRRQASRS

Sequences:

>Translated_344_residues
MSRWRSWLLLGIVVAALIGSALVVLGIGAVRVPVSDVARVVARRFRLIEGADVTVLNDQIVWQMRAPRVIGSMAVGALLA
MCGAVLQTLTGNDLADPYLLGISSGASVGAVFVLIVGISSTLGQSVLMTLASFIGAVVALVMVLTMATGRSGELPAGRTI
LAGVAVGQLCGAAVSVMIMIFGESNAARSALSWTLGSFAGLRWGSTITLVVATVPALVVGMALCHILDAFAFGDISAMSL
GVPVNTVRWAIMVSTALLTALSVAFAGPIGFVGLTVPHIVRFWTGSRHARLLPISALAGALLMVWSDTAARCLRPDTEIP
VGVITAIVGAPVLVVLLRRQASRS
>Mature_343_residues
SRWRSWLLLGIVVAALIGSALVVLGIGAVRVPVSDVARVVARRFRLIEGADVTVLNDQIVWQMRAPRVIGSMAVGALLAM
CGAVLQTLTGNDLADPYLLGISSGASVGAVFVLIVGISSTLGQSVLMTLASFIGAVVALVMVLTMATGRSGELPAGRTIL
AGVAVGQLCGAAVSVMIMIFGESNAARSALSWTLGSFAGLRWGSTITLVVATVPALVVGMALCHILDAFAFGDISAMSLG
VPVNTVRWAIMVSTALLTALSVAFAGPIGFVGLTVPHIVRFWTGSRHARLLPISALAGALLMVWSDTAARCLRPDTEIPV
GVITAIVGAPVLVVLLRRQASRS

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=329, Percent_Identity=34.6504559270517, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788004, Length=291, Percent_Identity=37.8006872852234, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1790741, Length=305, Percent_Identity=32.7868852459016, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1786347, Length=296, Percent_Identity=33.445945945946, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786805, Length=319, Percent_Identity=32.9153605015674, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1786804, Length=286, Percent_Identity=29.020979020979, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35473; Mature: 35342

Theoretical pI: Translated: 11.70; Mature: 11.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRWRSWLLLGIVVAALIGSALVVLGIGAVRVPVSDVARVVARRFRLIEGADVTVLNDQI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHCCCCEEEECCCE
VWQMRAPRVIGSMAVGALLAMCGAVLQTLTGNDLADPYLLGISSGASVGAVFVLIVGISS
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
TLGQSVLMTLASFIGAVVALVMVLTMATGRSGELPAGRTILAGVAVGQLCGAAVSVMIMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHE
FGESNAARSALSWTLGSFAGLRWGSTITLVVATVPALVVGMALCHILDAFAFGDISAMSL
ECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEE
GVPVNTVRWAIMVSTALLTALSVAFAGPIGFVGLTVPHIVRFWTGSRHARLLPISALAGA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHH
LLMVWSDTAARCLRPDTEIPVGVITAIVGAPVLVVLLRRQASRS
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRWRSWLLLGIVVAALIGSALVVLGIGAVRVPVSDVARVVARRFRLIEGADVTVLNDQI
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHCCCCEEEECCCE
VWQMRAPRVIGSMAVGALLAMCGAVLQTLTGNDLADPYLLGISSGASVGAVFVLIVGISS
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
TLGQSVLMTLASFIGAVVALVMVLTMATGRSGELPAGRTILAGVAVGQLCGAAVSVMIMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHE
FGESNAARSALSWTLGSFAGLRWGSTITLVVATVPALVVGMALCHILDAFAFGDISAMSL
ECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEE
GVPVNTVRWAIMVSTALLTALSVAFAGPIGFVGLTVPHIVRFWTGSRHARLLPISALAGA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHH
LLMVWSDTAARCLRPDTEIPVGVITAIVGAPVLVVLLRRQASRS
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]