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The map label for this gene is dapL [H]

Identifier: 50842115

GI number: 50842115

Start: 693906

End: 695009

Strand: Direct

Name: dapL [H]

Synonym: PPA0628

Alternate gene names: 50842115

Gene position: 693906-695009 (Clockwise)

Preceding gene: 50842114

Following gene: 50842119

Centisome position: 27.1

GC content: 60.96

Gene sequence:

>1104_bases
ATGAGTCGCCGTAACGTCTCTGCCAGCCTGCCTACCTTTCCTTGGGATACCATCGCCGAGGCCAGGCGTAAGGCTCAGTC
CCATCCCGACGGCATCGTCGATTTGTCGATGGGTACGCCGGTCGATCCCGCCCCGGGCGTTGCCATCGCGGCGCTTACGG
CGGCTGGTGACGCTCACGGTTACCCGCAGGTGTGGGGGACTCCTGCCCTGCGAGCCGGAATCCTGGATCACATGAAACAG
GTCTGGGGTGCGCCCGCCAGCCTTGAGGAGACTAGCGTTCTGCCAGTTATCGGGACCAAAGAGTTGGTGGCCTCCCTGCC
TGGCCAGCTTGGACTGGGGCCGGATTCGACCATCGTCATACCAGCGTGCGCCTATCCGACCTACCGGGTTGGTGCTCAGC
TTGCTGGGGCCAAGATTGTTGCCGTTAATGAGCCTGACGAGGTCGATGTCGCACCTGACCTTATCTGGATTAATTCCCCG
GCCAACCCGTCAGGTCGCGTCCTCGACCTTGACGAGATGAAAGCATGGGTGGATCTGGCGCGCAGCACGGGGGCTGTGCT
GGCCTCCGACGAGTGCTATGGCGAGTTTGTCTGGGAAGGGGAGTCGGTTTCGGTCCTAGACGAGAGAGTCAACAGCGGTG
ACGTCACCGGCTTACTGGCCTGCCTGTCGATGTCCAAGCGATCGAATATGGCCGGCTACCGCGCGGGGTTTGCCGTTGGG
GATGCTGAGTTGACCAGTGAGCTACTCACCGTGCGTAAGCACTCGGGACTCATGATTCCAGCCCCGGTGGTAGCTGCTAT
GCAGGCTGCCCTGGCAGATCGCTCCCATGTGCTTGAGCAAGTGAAGCGGTACCGGCTACGTCGCAATGTCCTGAAGCCAG
CTTTGGAGAAGGCCGGCTTCCGTATCGACCATTCCGAAGGGTCGCTGTACCTGTGGGCGACTCACGACGAGGACTGCCGG
GTTACTCTGGATCGACTAGCCGATCTGGGAATTCTCTGTTCTCCCGGTGATTTTTACGTTGCCGGTGGTTCCGACCATGT
CCGTATCGGACTGACGGCTACCGACGAGAGGATTAATGCCGCCGCCCAGCGGATACAGCCTTGA

Upstream 100 bases:

>100_bases
CCGAGTTCTTTAACGAGCTGGGATCCCCGGGCGGTGCTGCGCGGCTTGGCCCGACCCACAAGGACCACCCGGCCGTCGAA
ACCCTGCCCCCACAGGGCGA

Downstream 100 bases:

>100_bases
CTAGCTCCGAGCGGTGACGGTGCCGGAGACCCAGCCCGTCCCGCTGGCAGCTGGGCTCGCTGAGGGACCGGCGGCCGCGC
CCCATGAGGCGTAATGCTCG

Product: N-succinyldiaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSRRNVSASLPTFPWDTIAEARRKAQSHPDGIVDLSMGTPVDPAPGVAIAALTAAGDAHGYPQVWGTPALRAGILDHMKQ
VWGAPASLEETSVLPVIGTKELVASLPGQLGLGPDSTIVIPACAYPTYRVGAQLAGAKIVAVNEPDEVDVAPDLIWINSP
ANPSGRVLDLDEMKAWVDLARSTGAVLASDECYGEFVWEGESVSVLDERVNSGDVTGLLACLSMSKRSNMAGYRAGFAVG
DAELTSELLTVRKHSGLMIPAPVVAAMQAALADRSHVLEQVKRYRLRRNVLKPALEKAGFRIDHSEGSLYLWATHDEDCR
VTLDRLADLGILCSPGDFYVAGGSDHVRIGLTATDERINAAAQRIQP

Sequences:

>Translated_367_residues
MSRRNVSASLPTFPWDTIAEARRKAQSHPDGIVDLSMGTPVDPAPGVAIAALTAAGDAHGYPQVWGTPALRAGILDHMKQ
VWGAPASLEETSVLPVIGTKELVASLPGQLGLGPDSTIVIPACAYPTYRVGAQLAGAKIVAVNEPDEVDVAPDLIWINSP
ANPSGRVLDLDEMKAWVDLARSTGAVLASDECYGEFVWEGESVSVLDERVNSGDVTGLLACLSMSKRSNMAGYRAGFAVG
DAELTSELLTVRKHSGLMIPAPVVAAMQAALADRSHVLEQVKRYRLRRNVLKPALEKAGFRIDHSEGSLYLWATHDEDCR
VTLDRLADLGILCSPGDFYVAGGSDHVRIGLTATDERINAAAQRIQP
>Mature_366_residues
SRRNVSASLPTFPWDTIAEARRKAQSHPDGIVDLSMGTPVDPAPGVAIAALTAAGDAHGYPQVWGTPALRAGILDHMKQV
WGAPASLEETSVLPVIGTKELVASLPGQLGLGPDSTIVIPACAYPTYRVGAQLAGAKIVAVNEPDEVDVAPDLIWINSPA
NPSGRVLDLDEMKAWVDLARSTGAVLASDECYGEFVWEGESVSVLDERVNSGDVTGLLACLSMSKRSNMAGYRAGFAVGD
AELTSELLTVRKHSGLMIPAPVVAAMQAALADRSHVLEQVKRYRLRRNVLKPALEKAGFRIDHSEGSLYLWATHDEDCRV
TLDRLADLGILCSPGDFYVAGGSDHVRIGLTATDERINAAAQRIQP

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788722, Length=380, Percent_Identity=27.1052631578947, Blast_Score=133, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17567369, Length=334, Percent_Identity=23.3532934131737, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 39077; Mature: 38946

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRNVSASLPTFPWDTIAEARRKAQSHPDGIVDLSMGTPVDPAPGVAIAALTAAGDAHG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCC
YPQVWGTPALRAGILDHMKQVWGAPASLEETSVLPVIGTKELVASLPGQLGLGPDSTIVI
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCCCCEEEE
PACAYPTYRVGAQLAGAKIVAVNEPDEVDVAPDLIWINSPANPSGRVLDLDEMKAWVDLA
EECCCCCHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHH
RSTGAVLASDECYGEFVWEGESVSVLDERVNSGDVTGLLACLSMSKRSNMAGYRAGFAVG
HCCCCEEECCCCCEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHCCEEEC
DAELTSELLTVRKHSGLMIPAPVVAAMQAALADRSHVLEQVKRYRLRRNVLKPALEKAGF
HHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RIDHSEGSLYLWATHDEDCRVTLDRLADLGILCSPGDFYVAGGSDHVRIGLTATDERINA
EEECCCCCEEEEEECCCCHHHHHHHHHCCCEEECCCCEEEECCCCEEEEEEEECHHHHHH
AAQRIQP
HHHHCCC
>Mature Secondary Structure 
SRRNVSASLPTFPWDTIAEARRKAQSHPDGIVDLSMGTPVDPAPGVAIAALTAAGDAHG
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCC
YPQVWGTPALRAGILDHMKQVWGAPASLEETSVLPVIGTKELVASLPGQLGLGPDSTIVI
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCCCCEEEE
PACAYPTYRVGAQLAGAKIVAVNEPDEVDVAPDLIWINSPANPSGRVLDLDEMKAWVDLA
EECCCCCHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHH
RSTGAVLASDECYGEFVWEGESVSVLDERVNSGDVTGLLACLSMSKRSNMAGYRAGFAVG
HCCCCEEECCCCCEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHCCEEEC
DAELTSELLTVRKHSGLMIPAPVVAAMQAALADRSHVLEQVKRYRLRRNVLKPALEKAGF
HHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RIDHSEGSLYLWATHDEDCRVTLDRLADLGILCSPGDFYVAGGSDHVRIGLTATDERINA
EEECCCCCEEEEEECCCCHHHHHHHHHCCCEEECCCCEEEECCCCEEEEEEEECHHHHHH
AAQRIQP
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]