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The map label for this gene is moaCB [H]

Identifier: 50841997

GI number: 50841997

Start: 565188

End: 565688

Strand: Direct

Name: moaCB [H]

Synonym: PPA0513

Alternate gene names: 50841997

Gene position: 565188-565688 (Clockwise)

Preceding gene: 50841996

Following gene: 50841998

Centisome position: 22.08

GC content: 63.67

Gene sequence:

>501_bases
GTGGATGAGATCAGGGCACGCGTCATCACTGTCTCAGATCGTTGTGCCGCTGGCGCGGCCCTGGACCGGTCTGGGCCCTT
GGCTGCTTCATTGCTTGCTGAGCTGGGATGCAGCTGGCTCAAGGTCGATCCGGTGACTGTCGTACCTGACGGGATCGACT
CGGTGGGCGGCGCTTTGAGGGATGCACTAGAGAATGGATGCCGGCTTGTCGTCACTACCGGTGGAACGGGGATCTCGCCG
CGTGACCTTACCCCGGAAGCCACCGAGCCGTTGTTAGTGGCCCGTCTAGATGGGCTGGCCGAGCAGGTCCGAGCCCTCGG
TGCGCATGGCTCCGCCCTGGCAGGACTATCGCGTGGTCTCGTAGGTGTGACCTCACGGGGTGACCAAGCGGCTCTCATCA
TCAATGCGCCCGGCTCCACTGGCGGAGTGCGCGACACCCTCACTGTGATCGGGCCGATGCTCGAACACATCTTCAGGCAG
CTTGCCGGAGGAGGTCACTGA

Upstream 100 bases:

>100_bases
GAGGGGGCGGACTCCTGCCCCTCTAGAGGCGCACTCTTAGTGGCTTATGCCGAGCACGGGTCGGCGAGAGCGCTGATCGG
ATCTCGATAAGATCGATTGT

Downstream 100 bases:

>100_bases
CGTTCATGACTAGCGAGTTAGCACACACTGCATTTACTGAGTGCGGCGGACCGCACGTGCAGGCGTCCCTTCGGTTCGCT
GGATCGTAGGGTGTTTTTAA

Product: molybdenum cofactor biosynthesis protein

Products: NA

Alternate protein names: Molybdenum cofactor biosynthesis protein C; Molybdenum cofactor biosynthesis protein B [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MDEIRARVITVSDRCAAGAALDRSGPLAASLLAELGCSWLKVDPVTVVPDGIDSVGGALRDALENGCRLVVTTGGTGISP
RDLTPEATEPLLVARLDGLAEQVRALGAHGSALAGLSRGLVGVTSRGDQAALIINAPGSTGGVRDTLTVIGPMLEHIFRQ
LAGGGH

Sequences:

>Translated_166_residues
MDEIRARVITVSDRCAAGAALDRSGPLAASLLAELGCSWLKVDPVTVVPDGIDSVGGALRDALENGCRLVVTTGGTGISP
RDLTPEATEPLLVARLDGLAEQVRALGAHGSALAGLSRGLVGVTSRGDQAALIINAPGSTGGVRDTLTVIGPMLEHIFRQ
LAGGGH
>Mature_166_residues
MDEIRARVITVSDRCAAGAALDRSGPLAASLLAELGCSWLKVDPVTVVPDGIDSVGGALRDALENGCRLVVTTGGTGISP
RDLTPEATEPLLVARLDGLAEQVRALGAHGSALAGLSRGLVGVTSRGDQAALIINAPGSTGGVRDTLTVIGPMLEHIFRQ
LAGGGH

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=155, Percent_Identity=36.7741935483871, Blast_Score=80, Evalue=6e-16,
Organism=Homo sapiens, GI66932975, Length=155, Percent_Identity=36.7741935483871, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1786190, Length=148, Percent_Identity=32.4324324324324, Blast_Score=69, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17564954, Length=156, Percent_Identity=37.1794871794872, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17136978, Length=157, Percent_Identity=34.3949044585987, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24638841, Length=157, Percent_Identity=34.3949044585987, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR020817
- InterPro:   IPR012247
- InterPro:   IPR001453
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC; PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 16779; Mature: 16779

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEIRARVITVSDRCAAGAALDRSGPLAASLLAELGCSWLKVDPVTVVPDGIDSVGGALR
CCCHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCEEECCCCHHHHHHHHH
DALENGCRLVVTTGGTGISPRDLTPEATEPLLVARLDGLAEQVRALGAHGSALAGLSRGL
HHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
VGVTSRGDQAALIINAPGSTGGVRDTLTVIGPMLEHIFRQLAGGGH
EEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDEIRARVITVSDRCAAGAALDRSGPLAASLLAELGCSWLKVDPVTVVPDGIDSVGGALR
CCCHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCEEECCCCHHHHHHHHH
DALENGCRLVVTTGGTGISPRDLTPEATEPLLVARLDGLAEQVRALGAHGSALAGLSRGL
HHHHCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
VGVTSRGDQAALIINAPGSTGGVRDTLTVIGPMLEHIFRQLAGGGH
EEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]