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The map label for this gene is nudL [H]

Identifier: 50841718

GI number: 50841718

Start: 278693

End: 279349

Strand: Direct

Name: nudL [H]

Synonym: PPA0225

Alternate gene names: 50841718

Gene position: 278693-279349 (Clockwise)

Preceding gene: 50841717

Following gene: 50841722

Centisome position: 10.89

GC content: 62.86

Gene sequence:

>657_bases
ATGAGTCACTTAAGTGCCCTCATCGCCAGTCTTGGCCGTGACGACCCTGATTTTTCGGTGGGACGACGACCTGGCGGCGG
ACGATCCTCGGCGGTGCTGGCCCTTATCAGCGAGGAAGGGAACGACATTGTCCTGACTCGACGACCACTGTCCTTGCGTC
ACCATGCTGGACAGGTAGCCCTACCTGGGGGTCGGGCTGAGAACACTGACGAGACGATCGTCGATACCGCCCTGCGGGAA
GCCCACGAGGAGGTGGGATTGGACAGACGCCTCGTCACCGTGAGGGGAGTGCTGCCGACTGCCCACGTGGCTGCTAGCGG
CTCTGATGTCACGACCGTCATCGCCACCTGGAGTGGGGCAGGGACAGTTGGGGTCGTGGATCCCGCCGAGGTGGCCATGG
TGCAGCGTGTCAGACTGGCTGACCTGGCAAATCCGGCGGCTCGTGCCACCACACGTCACCCCTCGGGATATCGCGGTCCG
GCCTTCGTCCTACCCGACATATTCGTGTGGGGATTCACTGCCCATGTTCTCGACGCTTTGCTCGATCGCGGCGGATGGTC
CCGGCCGTGGGATCGGGAGCGCATGGTGGAGATTCCGGAAGGATATTTAGGGGCTCGACGTCTGCCGGAGGAGATGACGC
CGAACGACATTCCTTGA

Upstream 100 bases:

>100_bases
TCATCGTGCGCGACGGAACTATCGTCACCCGTCACAGTGGACAGTGGCGCTCCCAGCGGGAGCTTGACTCTGCTATTGAC
AAGGTCATTAAGAGGACGCC

Downstream 100 bases:

>100_bases
GGTGCGGGTTCCGCGCCTTGATGGCTACATCATAGGCAACGGCCCTCCCACATAGCTGTGGGAGGGCCGTAATAGTTAAC
TCAGTCGCGCTCGGTCGCAC

Product: putative NTP pyrophosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MSHLSALIASLGRDDPDFSVGRRPGGGRSSAVLALISEEGNDIVLTRRPLSLRHHAGQVALPGGRAENTDETIVDTALRE
AHEEVGLDRRLVTVRGVLPTAHVAASGSDVTTVIATWSGAGTVGVVDPAEVAMVQRVRLADLANPAARATTRHPSGYRGP
AFVLPDIFVWGFTAHVLDALLDRGGWSRPWDRERMVEIPEGYLGARRLPEEMTPNDIP

Sequences:

>Translated_218_residues
MSHLSALIASLGRDDPDFSVGRRPGGGRSSAVLALISEEGNDIVLTRRPLSLRHHAGQVALPGGRAENTDETIVDTALRE
AHEEVGLDRRLVTVRGVLPTAHVAASGSDVTTVIATWSGAGTVGVVDPAEVAMVQRVRLADLANPAARATTRHPSGYRGP
AFVLPDIFVWGFTAHVLDALLDRGGWSRPWDRERMVEIPEGYLGARRLPEEMTPNDIP
>Mature_217_residues
SHLSALIASLGRDDPDFSVGRRPGGGRSSAVLALISEEGNDIVLTRRPLSLRHHAGQVALPGGRAENTDETIVDTALREA
HEEVGLDRRLVTVRGVLPTAHVAASGSDVTTVIATWSGAGTVGVVDPAEVAMVQRVRLADLANPAARATTRHPSGYRGPA
FVLPDIFVWGFTAHVLDALLDRGGWSRPWDRERMVEIPEGYLGARRLPEEMTPNDIP

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI18859683, Length=156, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 23372; Mature: 23240

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLSALIASLGRDDPDFSVGRRPGGGRSSAVLALISEEGNDIVLTRRPLSLRHHAGQVA
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCHHHHCCCEEE
LPGGRAENTDETIVDTALREAHEEVGLDRRLVTVRGVLPTAHVAASGSDVTTVIATWSGA
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHCCCCCCEEEEEEECCCC
GTVGVVDPAEVAMVQRVRLADLANPAARATTRHPSGYRGPAFVLPDIFVWGFTAHVLDAL
CEEECCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHH
LDRGGWSRPWDRERMVEIPEGYLGARRLPEEMTPNDIP
HHCCCCCCCCCCCHHHCCCCCHHHHHCCCHHCCCCCCC
>Mature Secondary Structure 
SHLSALIASLGRDDPDFSVGRRPGGGRSSAVLALISEEGNDIVLTRRPLSLRHHAGQVA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCHHHHCCCEEE
LPGGRAENTDETIVDTALREAHEEVGLDRRLVTVRGVLPTAHVAASGSDVTTVIATWSGA
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHCCCCCCEEEEEEECCCC
GTVGVVDPAEVAMVQRVRLADLANPAARATTRHPSGYRGPAFVLPDIFVWGFTAHVLDAL
CEEECCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHH
LDRGGWSRPWDRERMVEIPEGYLGARRLPEEMTPNDIP
HHCCCCCCCCCCCHHHCCCCCHHHHHCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]