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The map label for this gene is nahA [H]

Identifier: 50841557

GI number: 50841557

Start: 67723

End: 69261

Strand: Reverse

Name: nahA [H]

Synonym: PPA0066

Alternate gene names: 50841557

Gene position: 69261-67723 (Counterclockwise)

Preceding gene: 50841559

Following gene: 50841549

Centisome position: 2.71

GC content: 64.39

Gene sequence:

>1539_bases
ATGCCCACCAACGACACCCTCATCCGGGGCTTGTGCCCCCAGCCCCGCCAGGTACAACTCACCGAAGGACAATTCCCCCT
GCCGTCGGTGCTCACCTGGACTGGCCCCGACGAGGTCATCAACGCCGTTACGATCCTCACCGAGCGACTGGCTCCAGCAC
TCGACGTCGTGCGAGCAACATCACACACCGACGATGCCTCCCTCACCGTCATAGTGGATCCCGCTTTAGAAGCGGAGGGC
TATCGCATTGACATCGACGCGCAGGTCCGCATCACTGTCGGCAGTCCATCTGGAGCGCGTTGGGCAGTGCAAACCCTGCT
CCAGCTGCTCACCCCGTGGGTTTACGGGCCCGGACCGCTAGCGCTGAAGCACCTATGCCTTCCGAAAGGCGTCATCGTCG
ATGCGCCACACCACAGTTGGCGCGGGGCCCATCTAGACGTTTCGCGGCATTTCATGCCCACCTCGTTCATCATGAACTTT
TTGGACGTGCTGGCCGTACACAAGCTCAATCGGCTGCACCTACATCTCACTGACGATCAGGGGTGGCGTCTGCCGGTACC
GGGCTGGCCGCGGCTGACCACGGTGGGCGCGTGGCGTCCAGGAACGGTACGAGGGCACCAACCGCCACCCGACGACAACG
GCTGTGACGACGTCGCTGAGCACGACCACATACCCCACGGTGGTGCCTACACCGTCGACCAGCTGCGCGCCATCGACGAG
CGAGCTCAGCTGTTGGGCATCACGGTCGTCCCGGAAGTCGATCTTCCGGGACACACCGAGTCGGTGGTGGCCGCCTACCC
CGAGTTGGGCTGTGGAGCACCGATCAGCCATCCGCGCACCGCCTTCGGGGTGTCGGAGCACCACATCAACCTCACCGATG
CTGCGCTGGGTTTTTGCCGCGACGTCCTGGATGCCGTGATGGAGATCTTCCCGAACTCGCCGATCCACATCGGCGGCGAC
GAGTGCCCCGGCAAGGAGTGGTTTGGACATAAGCCCACCCGCACCCGGCTAGCCGAGCTGGGCATCACGACCCCACACCA
GGCTCAGGCGTGGTTCGAGCGCCAGATCTGTGGCCACGTCGTCGCTGCTGGGCGTCAGGTCATCGCCTGGGACGAGGTGT
TGGAAGCCGGTGCGCCCGAGGAGGTCACCGTGATGGTGTGGCGGGATGCCGACGACATCGCCCGCGCTGCTGCCGCAGGT
CACGATGTCATTGCCGCACCCGCCCGGCATACCTACTTAGATCACGGCATGGAGACGGGCCCGCAGGCACCGGTGACAAT
CGACGCCCCGATGACTATGAACGATGTCGCCGGGCTGCACGACGTGCTGGCCGCGGTGAACTCACCCCACCTGCTGGGTG
GACAGTTCCAGTTGTGGACCGAATATCTGTGCACCCCTGCTCAGGTCGAGGATGCCGCCTTCCCGCGCGGCACGTCGATC
GCCGAACAGTTGTGGACTGGCAACCCGGCTCGACCGCTGTCGGAATTAGAGGCCCAAACTCGCCGTCTCACCGCGATGGG
GGTCAATTGGCACCGATAA

Upstream 100 bases:

>100_bases
TGGCTCCTGTGCGCGATTGGTCGCCCTTCAGCATAGACAGCTACTAACCCCGGTAACCTGTGAAACACCCCATTGGCAGG
CGATGCCCCGAGGAGTAGAG

Downstream 100 bases:

>100_bases
TGGCATCGATACCGGCCACGTTCATCATGAGCAGGCAGGCCATCGAGTTCGACCAACTGAACCACCCTCGGGTGAACCGA
GTAGGGTCGGTTGGATCGAA

Product: glycosyl hydrolase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MPTNDTLIRGLCPQPRQVQLTEGQFPLPSVLTWTGPDEVINAVTILTERLAPALDVVRATSHTDDASLTVIVDPALEAEG
YRIDIDAQVRITVGSPSGARWAVQTLLQLLTPWVYGPGPLALKHLCLPKGVIVDAPHHSWRGAHLDVSRHFMPTSFIMNF
LDVLAVHKLNRLHLHLTDDQGWRLPVPGWPRLTTVGAWRPGTVRGHQPPPDDNGCDDVAEHDHIPHGGAYTVDQLRAIDE
RAQLLGITVVPEVDLPGHTESVVAAYPELGCGAPISHPRTAFGVSEHHINLTDAALGFCRDVLDAVMEIFPNSPIHIGGD
ECPGKEWFGHKPTRTRLAELGITTPHQAQAWFERQICGHVVAAGRQVIAWDEVLEAGAPEEVTVMVWRDADDIARAAAAG
HDVIAAPARHTYLDHGMETGPQAPVTIDAPMTMNDVAGLHDVLAAVNSPHLLGGQFQLWTEYLCTPAQVEDAAFPRGTSI
AEQLWTGNPARPLSELEAQTRRLTAMGVNWHR

Sequences:

>Translated_512_residues
MPTNDTLIRGLCPQPRQVQLTEGQFPLPSVLTWTGPDEVINAVTILTERLAPALDVVRATSHTDDASLTVIVDPALEAEG
YRIDIDAQVRITVGSPSGARWAVQTLLQLLTPWVYGPGPLALKHLCLPKGVIVDAPHHSWRGAHLDVSRHFMPTSFIMNF
LDVLAVHKLNRLHLHLTDDQGWRLPVPGWPRLTTVGAWRPGTVRGHQPPPDDNGCDDVAEHDHIPHGGAYTVDQLRAIDE
RAQLLGITVVPEVDLPGHTESVVAAYPELGCGAPISHPRTAFGVSEHHINLTDAALGFCRDVLDAVMEIFPNSPIHIGGD
ECPGKEWFGHKPTRTRLAELGITTPHQAQAWFERQICGHVVAAGRQVIAWDEVLEAGAPEEVTVMVWRDADDIARAAAAG
HDVIAAPARHTYLDHGMETGPQAPVTIDAPMTMNDVAGLHDVLAAVNSPHLLGGQFQLWTEYLCTPAQVEDAAFPRGTSI
AEQLWTGNPARPLSELEAQTRRLTAMGVNWHR
>Mature_511_residues
PTNDTLIRGLCPQPRQVQLTEGQFPLPSVLTWTGPDEVINAVTILTERLAPALDVVRATSHTDDASLTVIVDPALEAEGY
RIDIDAQVRITVGSPSGARWAVQTLLQLLTPWVYGPGPLALKHLCLPKGVIVDAPHHSWRGAHLDVSRHFMPTSFIMNFL
DVLAVHKLNRLHLHLTDDQGWRLPVPGWPRLTTVGAWRPGTVRGHQPPPDDNGCDDVAEHDHIPHGGAYTVDQLRAIDER
AQLLGITVVPEVDLPGHTESVVAAYPELGCGAPISHPRTAFGVSEHHINLTDAALGFCRDVLDAVMEIFPNSPIHIGGDE
CPGKEWFGHKPTRTRLAELGITTPHQAQAWFERQICGHVVAAGRQVIAWDEVLEAGAPEEVTVMVWRDADDIARAAAAGH
DVIAAPARHTYLDHGMETGPQAPVTIDAPMTMNDVAGLHDVLAAVNSPHLLGGQFQLWTEYLCTPAQVEDAAFPRGTSIA
EQLWTGNPARPLSELEAQTRRLTAMGVNWHR

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=406, Percent_Identity=25.3694581280788, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI189181666, Length=447, Percent_Identity=27.0693512304251, Blast_Score=108, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17569815, Length=376, Percent_Identity=25.2659574468085, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281365639, Length=455, Percent_Identity=25.7142857142857, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24657474, Length=455, Percent_Identity=25.7142857142857, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24657468, Length=455, Percent_Identity=25.7142857142857, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17647501, Length=455, Percent_Identity=25.7142857142857, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24653074, Length=430, Percent_Identity=24.8837209302326, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45551090, Length=430, Percent_Identity=24.8837209302326, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17933586, Length=463, Percent_Identity=24.8380129589633, Blast_Score=90, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 55785; Mature: 55654

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTNDTLIRGLCPQPRQVQLTEGQFPLPSVLTWTGPDEVINAVTILTERLAPALDVVRAT
CCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHC
SHTDDASLTVIVDPALEAEGYRIDIDAQVRITVGSPSGARWAVQTLLQLLTPWVYGPGPL
CCCCCCEEEEEECCCCCCCCEEEEECEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHH
ALKHLCLPKGVIVDAPHHSWRGAHLDVSRHFMPTSFIMNFLDVLAVHKLNRLHLHLTDDQ
HHHHHHCCCCEEEECCCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEECCC
GWRLPVPGWPRLTTVGAWRPGTVRGHQPPPDDNGCDDVAEHDHIPHGGAYTVDQLRAIDE
CCEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHH
RAQLLGITVVPEVDLPGHTESVVAAYPELGCGAPISHPRTAFGVSEHHINLTDAALGFCR
HHHEEEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHH
DVLDAVMEIFPNSPIHIGGDECPGKEWFGHKPTRTRLAELGITTPHQAQAWFERQICGHV
HHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VAAGRQVIAWDEVLEAGAPEEVTVMVWRDADDIARAAAAGHDVIAAPARHTYLDHGMETG
HHCCCEEEEHHHHHHCCCCCCEEEEEEECHHHHHHHHHCCCCEEECCHHHHHHHCCCCCC
PQAPVTIDAPMTMNDVAGLHDVLAAVNSPHLLGGQFQLWTEYLCTPAQVEDAAFPRGTSI
CCCCEEEECCCCHHHHHHHHHHHHHHCCCCEECCHHHHHHHHCCCCCCCCCCCCCCCCHH
AEQLWTGNPARPLSELEAQTRRLTAMGVNWHR
HHHHHCCCCCCCHHHHHHHHHHEEEECCCCCC
>Mature Secondary Structure 
PTNDTLIRGLCPQPRQVQLTEGQFPLPSVLTWTGPDEVINAVTILTERLAPALDVVRAT
CCCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHC
SHTDDASLTVIVDPALEAEGYRIDIDAQVRITVGSPSGARWAVQTLLQLLTPWVYGPGPL
CCCCCCEEEEEECCCCCCCCEEEEECEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHH
ALKHLCLPKGVIVDAPHHSWRGAHLDVSRHFMPTSFIMNFLDVLAVHKLNRLHLHLTDDQ
HHHHHHCCCCEEEECCCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEECCC
GWRLPVPGWPRLTTVGAWRPGTVRGHQPPPDDNGCDDVAEHDHIPHGGAYTVDQLRAIDE
CCEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHH
RAQLLGITVVPEVDLPGHTESVVAAYPELGCGAPISHPRTAFGVSEHHINLTDAALGFCR
HHHEEEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHH
DVLDAVMEIFPNSPIHIGGDECPGKEWFGHKPTRTRLAELGITTPHQAQAWFERQICGHV
HHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VAAGRQVIAWDEVLEAGAPEEVTVMVWRDADDIARAAAAGHDVIAAPARHTYLDHGMETG
HHCCCEEEEHHHHHHCCCCCCEEEEEEECHHHHHHHHHCCCCEEECCHHHHHHHCCCCCC
PQAPVTIDAPMTMNDVAGLHDVLAAVNSPHLLGGQFQLWTEYLCTPAQVEDAAFPRGTSI
CCCCEEEECCCCHHHHHHHHHHHHHHCCCCEECCHHHHHHHHCCCCCCCCCCCCCCCCHH
AEQLWTGNPARPLSELEAQTRRLTAMGVNWHR
HHHHHCCCCCCCHHHHHHHHHHEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]