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The map label for this gene is glpR [H]

Identifier: 50841523

GI number: 50841523

Start: 30784

End: 31542

Strand: Direct

Name: glpR [H]

Synonym: PPA0031

Alternate gene names: 50841523

Gene position: 30784-31542 (Clockwise)

Preceding gene: 50841514

Following gene: 50841524

Centisome position: 1.2

GC content: 62.19

Gene sequence:

>759_bases
ATGCAACGATTATTTCGCCAGAAAATGATCATCAACTCTCTCGGGACCTCACCGACCTCGGTGGATACACTCGTGGAGCT
CACCGGCGCCTCGCCGGCGACGATCCGCCGTGACCTCACCGACCTTGAAGGCCACGGACAGTTGCGCAAGGTGCATGGCG
GGGCAGTGGCGGTGAACCTGCGCGGCACGCCGATGCCTTACTCCCTGCGGTCGGCCGAGAATGCTGAAAGCAAGACTGCC
ATAGCTCAGCTGGTCTCCCGCCTCGTGACTGACGACATGTCCGTGATCATCGACAACGGCTCGACCATGGTTGCCGTGGC
GCAGGCCCTTCAGGAACGCCCCATCACGGCTTTGTGTCTCTCGTTGCGCGCCGCGCTGCCCCTGGGCGAAGGCGGCGTGG
CTACCGTGAGCACGCCGGATGGAACGCTTATGCCCGAGAGCCTGCGCTACGCGGCTGCTTCATGTTTGCGTGCACTGGGT
GAGTTCCGGGCTGATGTCGCCATCGTCGGCACATGTTCTGCCTCTCCTGCCATGGGTCTGACGGTCACGACGCATCAAGA
TGCCCAGGTGAAACGCGCCATCCTCGCGTCCTCGGCCCGGGTCGTTTTGGCTGCCACGGGTGACAAGCTCTCACGAACCT
CAAGTTTTCGCTTCGGCGACATCGAGGACATCGACGATTTGGTCACCACGCGAGATGCGCCTCAGGTAACGCTTGACGCT
TTCCGGGTTGCGGGAAGCAGGGTTTACGTCGCTGACTGA

Upstream 100 bases:

>100_bases
CACACGCTTGCGGTGATGGCCAGGCCCTTGGTGCTGAGGACGGCCCAGATTCGCTGCCATATATGAGCCACGCCACTAGC
GTGCATGATTAAATAATCAT

Downstream 100 bases:

>100_bases
CTAGCTCCGAGGAACGCACGACTCTCGGCTACCTAGAGAATCTCTTGCAGGATCCGGCGGCCATGTTGAGTCTTAGGTGC
CCAAGACCGTCGCCTCCTAT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MQRLFRQKMIINSLGTSPTSVDTLVELTGASPATIRRDLTDLEGHGQLRKVHGGAVAVNLRGTPMPYSLRSAENAESKTA
IAQLVSRLVTDDMSVIIDNGSTMVAVAQALQERPITALCLSLRAALPLGEGGVATVSTPDGTLMPESLRYAAASCLRALG
EFRADVAIVGTCSASPAMGLTVTTHQDAQVKRAILASSARVVLAATGDKLSRTSSFRFGDIEDIDDLVTTRDAPQVTLDA
FRVAGSRVYVAD

Sequences:

>Translated_252_residues
MQRLFRQKMIINSLGTSPTSVDTLVELTGASPATIRRDLTDLEGHGQLRKVHGGAVAVNLRGTPMPYSLRSAENAESKTA
IAQLVSRLVTDDMSVIIDNGSTMVAVAQALQERPITALCLSLRAALPLGEGGVATVSTPDGTLMPESLRYAAASCLRALG
EFRADVAIVGTCSASPAMGLTVTTHQDAQVKRAILASSARVVLAATGDKLSRTSSFRFGDIEDIDDLVTTRDAPQVTLDA
FRVAGSRVYVAD
>Mature_252_residues
MQRLFRQKMIINSLGTSPTSVDTLVELTGASPATIRRDLTDLEGHGQLRKVHGGAVAVNLRGTPMPYSLRSAENAESKTA
IAQLVSRLVTDDMSVIIDNGSTMVAVAQALQERPITALCLSLRAALPLGEGGVATVSTPDGTLMPESLRYAAASCLRALG
EFRADVAIVGTCSASPAMGLTVTTHQDAQVKRAILASSARVVLAATGDKLSRTSSFRFGDIEDIDDLVTTRDAPQVTLDA
FRVAGSRVYVAD

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=225, Percent_Identity=29.7777777777778, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789519, Length=247, Percent_Identity=23.8866396761134, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790635, Length=234, Percent_Identity=25.6410256410256, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789059, Length=227, Percent_Identity=27.7533039647577, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082344, Length=217, Percent_Identity=26.2672811059908, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26541; Mature: 26541

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRLFRQKMIINSLGTSPTSVDTLVELTGASPATIRRDLTDLEGHGQLRKVHGGAVAVNL
CHHHHHHHHHHHHCCCCCCCHHHHHEECCCCHHHHHHHHHCCCCCCCEEEECCCEEEEEE
RGTPMPYSLRSAENAESKTAIAQLVSRLVTDDMSVIIDNGSTMVAVAQALQERPITALCL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCHHHHHH
SLRAALPLGEGGVATVSTPDGTLMPESLRYAAASCLRALGEFRADVAIVGTCSASPAMGL
HHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEE
TVTTHQDAQVKRAILASSARVVLAATGDKLSRTSSFRFGDIEDIDDLVTTRDAPQVTLDA
EEECCCCHHHHHHHHHCCCEEEEEECCCCHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHH
FRVAGSRVYVAD
HHHCCCEEEEEC
>Mature Secondary Structure
MQRLFRQKMIINSLGTSPTSVDTLVELTGASPATIRRDLTDLEGHGQLRKVHGGAVAVNL
CHHHHHHHHHHHHCCCCCCCHHHHHEECCCCHHHHHHHHHCCCCCCCEEEECCCEEEEEE
RGTPMPYSLRSAENAESKTAIAQLVSRLVTDDMSVIIDNGSTMVAVAQALQERPITALCL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCHHHHHH
SLRAALPLGEGGVATVSTPDGTLMPESLRYAAASCLRALGEFRADVAIVGTCSASPAMGL
HHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEE
TVTTHQDAQVKRAILASSARVVLAATGDKLSRTSSFRFGDIEDIDDLVTTRDAPQVTLDA
EEECCCCHHHHHHHHHCCCEEEEEECCCCHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHH
FRVAGSRVYVAD
HHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]