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The map label for this gene is pgsA [H]

Identifier: 50365478

GI number: 50365478

Start: 769418

End: 770035

Strand: Reverse

Name: pgsA [H]

Synonym: Mfl663

Alternate gene names: 50365478

Gene position: 770035-769418 (Counterclockwise)

Preceding gene: 50365479

Following gene: 50365477

Centisome position: 97.08

GC content: 25.89

Gene sequence:

>618_bases
ATGAAACAAAAACAAAAATTAAATCTACCTAATTGATTAACTCTAATAAGATTACTTTTAGTTCCTGTTGTTGTTATGCT
TGTTATATCAAACATTTGTGATTGAGATAAAAGTTTTATAATTGGAACTGACACTTCAACATTCCATATAACATTAACAA
TGCTATTAGCTGGTATTGTATTCATCGTAGCAAGTTTCACAGATTTTTTAGATGGATACTTAGCTAGAAAGAATAATCAA
GTTACAGAATTTGGGAAATTCTTTGACCCAATAGCAGACAAACTTCTTGTTAATGCAACTTTAATTTTATTCGCTTCAAG
TATTTCTATAATACCTGTTTGAGTAACTTTAGTCTTAATCCTAAGAGATATATTTGTAGATTTTATTAGAATGATATTGA
GTTCAAAAAATATAACTTTATCTGCAGGAATTTTTGGAAAATTAAAAACAGTTTTCCAAATGATTGGATTATCAATCTTA
TTCTTTTTTAGCTCATTTACTCTTAATATAGAAGTTTGACAAGAACAATTGATTTTAATTCCAATGTATATAGCTGTAGC
TTTCAGTTTATATAGTGGTTTGGATTATTTCTTAAAAGCAAGAAAAAATTTATTTTAG

Upstream 100 bases:

>100_bases
AATCCATTTGAAAATGGATTTGAAGGCGAAATTGATAAAGACATGAAAGTTAATAACTGAATGGCAGCCAAAGAAGCCCA
AGAACTTAGAGAAATAAACA

Downstream 100 bases:

>100_bases
TAAACAAAGGAACTTATGTTCCTTTTTATTTAGCAATCTTAAAAAGAAGGTATGTGCTATAATAATTTAAGTTAAAAGAA
GAAAAGGAGATGTGAACAAT

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MKQKQKLNLPNWLTLIRLLLVPVVVMLVISNICDWDKSFIIGTDTSTFHITLTMLLAGIVFIVASFTDFLDGYLARKNNQ
VTEFGKFFDPIADKLLVNATLILFASSISIIPVWVTLVLILRDIFVDFIRMILSSKNITLSAGIFGKLKTVFQMIGLSIL
FFFSSFTLNIEVWQEQLILIPMYIAVAFSLYSGLDYFLKARKNLF

Sequences:

>Translated_205_residues
MKQKQKLNLPN*LTLIRLLLVPVVVMLVISNICD*DKSFIIGTDTSTFHITLTMLLAGIVFIVASFTDFLDGYLARKNNQ
VTEFGKFFDPIADKLLVNATLILFASSISIIPV*VTLVLILRDIFVDFIRMILSSKNITLSAGIFGKLKTVFQMIGLSIL
FFFSSFTLNIEV*QEQLILIPMYIAVAFSLYSGLDYFLKARKNLF
>Mature_205_residues
MKQKQKLNLPN*LTLIRLLLVPVVVMLVISNICD*DKSFIIGTDTSTFHITLTMLLAGIVFIVASFTDFLDGYLARKNNQ
VTEFGKFFDPIADKLLVNATLILFASSISIIPV*VTLVLILRDIFVDFIRMILSSKNITLSAGIFGKLKTVFQMIGLSIL
FFFSSFTLNIEV*QEQLILIPMYIAVAFSLYSGLDYFLKARKNLF

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=202, Percent_Identity=32.1782178217822, Blast_Score=94, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22533; Mature: 22533

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQKQKLNLPNLTLIRLLLVPVVVMLVISNICDDKSFIIGTDTSTFHITLTMLLAGIVFI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHH
VASFTDFLDGYLARKNNQVTEFGKFFDPIADKLLVNATLILFASSISIIPVVTLVLILRD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IFVDFIRMILSSKNITLSAGIFGKLKTVFQMIGLSILFFFSSFTLNIEVQEQLILIPMYI
HHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHH
AVAFSLYSGLDYFLKARKNLF
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQKQKLNLPNLTLIRLLLVPVVVMLVISNICDDKSFIIGTDTSTFHITLTMLLAGIVFI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHH
VASFTDFLDGYLARKNNQVTEFGKFFDPIADKLLVNATLILFASSISIIPVVTLVLILRD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IFVDFIRMILSSKNITLSAGIFGKLKTVFQMIGLSILFFFSSFTLNIEVQEQLILIPMYI
HHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHH
AVAFSLYSGLDYFLKARKNLF
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA