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The map label for this gene is hprK [H]

Identifier: 50364877

GI number: 50364877

Start: 80225

End: 81157

Strand: Direct

Name: hprK [H]

Synonym: Mfl062

Alternate gene names: 50364877

Gene position: 80225-81157 (Clockwise)

Preceding gene: 50364876

Following gene: 50364878

Centisome position: 10.11

GC content: 27.22

Gene sequence:

>933_bases
ATGAGTAAATTAACAATAAAAGAATTAGTAAATAAGTTTGATTTTGAGATCATTTCAGGAGCTGAACATATTGATAGTGA
AATAACAGTTTATGGACTTAACCGTGCTGGATTAGAGTTAACAGGTTATTTCAATGAAAAAGAAGATAAGAAACATAAAC
GTGCAATTTTAATGTCTTCAAAAGAAAATAATTATATGTCTCAATTTTCTGATGAAGAAGCATATGAAAAATATAAAAAC
CTAATTAAAATGGGTTCTCCAGTAATAATAGTTACTCAAAAATTTACAGATGAAAGATTGAGTAAAATAGCAAAGGAATT
TAACTTTCCGTTATTAAAAATTAATTACCCATCAACAAGTGAATTAACACAAAAAATATTAGATATTTATGATTTATATT
TTGCTCCTACAATAGAAGTGCATTCTACATTAATGAATATTTATGGAAAAGGAGTTCTTATCTTTGGACAATCAGGAATT
GGTAAATCAGAAGTATCTCTAGAATTAATGAAAAAAAACCACTTGTTTGTTGGTGATGATAGAATAGTTATTTCAAATAG
AAATAGTGAATTATTTGGTAAATCACATGCTCTTTTACAAAATTTAATTGAGGTTAGAGGAATTGGAATAATAGATATTT
CAAAAGTTCAAGGACAACAATTAATAATGCCTGAGACAAAGATACATATGGGTATTGAATTATTTAAATTTCAAGAAGGT
GGAATTGACAATACTGATAGATTAGGCAATGAATGAACTCAAAAAGATTTCTTAGGATTAAAAATACCTTACTTAAGAGT
TCCTGTTAGTGCAGGACGAAACTTAGCAAATATTATAGAAGCCGCAGTTGGGCAATTAAAAGTTAACGAAAGTTCTGATG
CTCAAGATATTATTGAATTATTAGCTAAAAGAAATAGTGAATTAGCAGAATAG

Upstream 100 bases:

>100_bases
AAAGCAAATAAGTAGTTTGCTTTTTTATATTTGCTCACTATTATTTTTTTAATAAACAATTATAGTAAAATTATAATAAT
AAAAACAAGGAGTTTTAAAG

Downstream 100 bases:

>100_bases
AGGAAAAATGTGACAACAATACCAAGATTTTTATAGATGAATAAATATATCTAATAAAACACCTGAAGACATGCGTCTTC
TTTTTGGTCTTGTCCCAGCA

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSKLTIKELVNKFDFEIISGAEHIDSEITVYGLNRAGLELTGYFNEKEDKKHKRAILMSSKENNYMSQFSDEEAYEKYKN
LIKMGSPVIIVTQKFTDERLSKIAKEFNFPLLKINYPSTSELTQKILDIYDLYFAPTIEVHSTLMNIYGKGVLIFGQSGI
GKSEVSLELMKKNHLFVGDDRIVISNRNSELFGKSHALLQNLIEVRGIGIIDISKVQGQQLIMPETKIHMGIELFKFQEG
GIDNTDRLGNEWTQKDFLGLKIPYLRVPVSAGRNLANIIEAAVGQLKVNESSDAQDIIELLAKRNSELAE

Sequences:

>Translated_310_residues
MSKLTIKELVNKFDFEIISGAEHIDSEITVYGLNRAGLELTGYFNEKEDKKHKRAILMSSKENNYMSQFSDEEAYEKYKN
LIKMGSPVIIVTQKFTDERLSKIAKEFNFPLLKINYPSTSELTQKILDIYDLYFAPTIEVHSTLMNIYGKGVLIFGQSGI
GKSEVSLELMKKNHLFVGDDRIVISNRNSELFGKSHALLQNLIEVRGIGIIDISKVQGQQLIMPETKIHMGIELFKFQEG
GIDNTDRLGNE*TQKDFLGLKIPYLRVPVSAGRNLANIIEAAVGQLKVNESSDAQDIIELLAKRNSELAE
>Mature_309_residues
SKLTIKELVNKFDFEIISGAEHIDSEITVYGLNRAGLELTGYFNEKEDKKHKRAILMSSKENNYMSQFSDEEAYEKYKNL
IKMGSPVIIVTQKFTDERLSKIAKEFNFPLLKINYPSTSELTQKILDIYDLYFAPTIEVHSTLMNIYGKGVLIFGQSGIG
KSEVSLELMKKNHLFVGDDRIVISNRNSELFGKSHALLQNLIEVRGIGIIDISKVQGQQLIMPETKIHMGIELFKFQEGG
IDNTDRLGNE*TQKDFLGLKIPYLRVPVSAGRNLANIIEAAVGQLKVNESSDAQDIIELLAKRNSELAE

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 34865; Mature: 34733

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLTIKELVNKFDFEIISGAEHIDSEITVYGLNRAGLELTGYFNEKEDKKHKRAILMSS
CCCCCHHHHHHHHCHHEECCHHHCCCCEEEEECCCCCEEEEECCCCCHHHHHHHEEEEEC
KENNYMSQFSDEEAYEKYKNLIKMGSPVIIVTQKFTDERLSKIAKEFNFPLLKINYPSTS
CCCCHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEECCCHH
ELTQKILDIYDLYFAPTIEVHSTLMNIYGKGVLIFGQSGIGKSEVSLELMKKNHLFVGDD
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHEEHHCCCEEECCC
RIVISNRNSELFGKSHALLQNLIEVRGIGIIDISKVQGQQLIMPETKIHMGIELFKFQEG
EEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCHHHHCCEEEEEECCC
GIDNTDRLGNETQKDFLGLKIPYLRVPVSAGRNLANIIEAAVGQLKVNESSDAQDIIELL
CCCCHHHCCCHHHHHHCCEECCEEEEEHHHCCCHHHHHHHHHHCEEECCCCCHHHHHHHH
AKRNSELAE
HHCCCCCCC
>Mature Secondary Structure 
SKLTIKELVNKFDFEIISGAEHIDSEITVYGLNRAGLELTGYFNEKEDKKHKRAILMSS
CCCCHHHHHHHHCHHEECCHHHCCCCEEEEECCCCCEEEEECCCCCHHHHHHHEEEEEC
KENNYMSQFSDEEAYEKYKNLIKMGSPVIIVTQKFTDERLSKIAKEFNFPLLKINYPSTS
CCCCHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEECCCHH
ELTQKILDIYDLYFAPTIEVHSTLMNIYGKGVLIFGQSGIGKSEVSLELMKKNHLFVGDD
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHEEHHCCCEEECCC
RIVISNRNSELFGKSHALLQNLIEVRGIGIIDISKVQGQQLIMPETKIHMGIELFKFQEG
EEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCHHHHCCEEEEEECCC
GIDNTDRLGNETQKDFLGLKIPYLRVPVSAGRNLANIIEAAVGQLKVNESSDAQDIIELL
CCCCHHHCCCHHHHHHCCEECCEEEEEHHHCCCHHHHHHHHHHCEEECCCCCHHHHHHHH
AKRNSELAE
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA