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The map label for this gene is nanK [H]

Identifier: 50364828

GI number: 50364828

Start: 17728

End: 18645

Strand: Direct

Name: nanK [H]

Synonym: Mfl013

Alternate gene names: 50364828

Gene position: 17728-18645 (Clockwise)

Preceding gene: 50364827

Following gene: 50364833

Centisome position: 2.23

GC content: 26.14

Gene sequence:

>918_bases
ATGAAATATTATACTTTTGATATAGGTGGAACATCTACAAAGTACCTAATTTTTGAAGATAAAAAAGTTATTAAATCTGG
CGTAATTGAGTATAAAGAACAAATGAAAGAAAAAGGTTCAATTAGAGACAAAATAACTTTAACTAAAATATTTGATGAAA
TATCAGTTATGCTTGAAAATGAAAGTATGGATTTTTGTTTAGGGCTATCAATTCCAGGTATTGTAGATAGTAAAAACCAA
AAAATTTTAAGTGATTCTGGAATATCTGAAACAAATATCGATATTCAAGATTACTTTAAAAAATTTAAGAATATTATTAA
ATTAAGTATTGAAAACGATGCTAAATCAGCAGCATATGGTGAATTTTATTTTGGACAAGATCAAAAACCTATAAATATGG
TACATCTGACTTTTGGTACAGGATTAGGTTGCGGAATTATTATAAATAAAGAAATTTATAGAACAATAAATCATAAGGCC
GGAGAAATTGGCAAAAGTTATTCAAACATAAATAGCACAGAGTCAGTTGTAGTAATGGACACAAGCGTTATTGCAATATT
AATAAAATATAAAATGGCAACAGGAAAAGAAATAAGTGGAAAAGAATTCTTTGAATTATACGAGAAAAAAGACCCTTTAG
TTCAAAAATTAATGAAGGATTGAACATCAGCTGTTGCAAGAACCATTATTGGATTAGATTATAGTTTTGACTTTGATTTA
TTAACAATTGGTGGTGGCGTTAGCGATAATAAAATTTTTCAAAAACTTTTATTTGAAGAACTTGATTTAAATAAAGACTT
TGAATTTATGGGAAATAAACTATCATCAAATGGTCAAACAATAAGCAAAGTAAAAATATCTAATTTAAAAAATGATGCAG
GTTGTTACGGAATGTTGGCAATTTTAAAACAAAATTAA

Upstream 100 bases:

>100_bases
TTATGATGATTATCATAGAGGAACAGGGAATAGATTTAAGAAAAAATCTTTTACTTGATTCCAAAACTTTATGAAAACAA
GCGAAGTTTAAGGAGATAAA

Downstream 100 bases:

>100_bases
TAAAAAAACAAAGTTTAAAATTAAGACTTTGTTTTTTATTTACCTAAACAATACTTTTTGAATATATTATCAATTATTTC
TTCGTCATATTGCTCACCAA

Product: transcriptional regulator/sugar kinase

Products: NA

Alternate protein names: ManNAc kinase; N-acetyl-D-mannosamine kinase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKYYTFDIGGTSTKYLIFEDKKVIKSGVIEYKEQMKEKGSIRDKITLTKIFDEISVMLENESMDFCLGLSIPGIVDSKNQ
KILSDSGISETNIDIQDYFKKFKNIIKLSIENDAKSAAYGEFYFGQDQKPINMVHLTFGTGLGCGIIINKEIYRTINHKA
GEIGKSYSNINSTESVVVMDTSVIAILIKYKMATGKEISGKEFFELYEKKDPLVQKLMKDWTSAVARTIIGLDYSFDFDL
LTIGGGVSDNKIFQKLLFEELDLNKDFEFMGNKLSSNGQTISKVKISNLKNDAGCYGMLAILKQN

Sequences:

>Translated_305_residues
MKYYTFDIGGTSTKYLIFEDKKVIKSGVIEYKEQMKEKGSIRDKITLTKIFDEISVMLENESMDFCLGLSIPGIVDSKNQ
KILSDSGISETNIDIQDYFKKFKNIIKLSIENDAKSAAYGEFYFGQDQKPINMVHLTFGTGLGCGIIINKEIYRTINHKA
GEIGKSYSNINSTESVVVMDTSVIAILIKYKMATGKEISGKEFFELYEKKDPLVQKLMKD*TSAVARTIIGLDYSFDFDL
LTIGGGVSDNKIFQKLLFEELDLNKDFEFMGNKLSSNGQTISKVKISNLKNDAGCYGMLAILKQN
>Mature_305_residues
MKYYTFDIGGTSTKYLIFEDKKVIKSGVIEYKEQMKEKGSIRDKITLTKIFDEISVMLENESMDFCLGLSIPGIVDSKNQ
KILSDSGISETNIDIQDYFKKFKNIIKLSIENDAKSAAYGEFYFGQDQKPINMVHLTFGTGLGCGIIINKEIYRTINHKA
GEIGKSYSNINSTESVVVMDTSVIAILIKYKMATGKEISGKEFFELYEKKDPLVQKLMKD*TSAVARTIIGLDYSFDFDL
LTIGGGVSDNKIFQKLLFEELDLNKDFEFMGNKLSSNGQTISKVKISNLKNDAGCYGMLAILKQN

Specific function: Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family. NanK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.60 [H]

Molecular weight: Translated: 34124; Mature: 34124

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYYTFDIGGTSTKYLIFEDKKVIKSGVIEYKEQMKEKGSIRDKITLTKIFDEISVMLEN
CEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECC
ESMDFCLGLSIPGIVDSKNQKILSDSGISETNIDIQDYFKKFKNIIKLSIENDAKSAAYG
CCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHEEEEECCCCCCCCCC
EFYFGQDQKPINMVHLTFGTGLGCGIIINKEIYRTINHKAGEIGKSYSNINSTESVVVMD
CEEECCCCCCEEEEEEEECCCCCEEEEECHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEE
TSVIAILIKYKMATGKEISGKEFFELYEKKDPLVQKLMKDTSAVARTIIGLDYSFDFDLL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
TIGGGVSDNKIFQKLLFEELDLNKDFEFMGNKLSSNGQTISKVKISNLKNDAGCYGMLAI
EECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEEEEEEECCCCCCCCHHEEEEE
LKQN
EECC
>Mature Secondary Structure
MKYYTFDIGGTSTKYLIFEDKKVIKSGVIEYKEQMKEKGSIRDKITLTKIFDEISVMLEN
CEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECC
ESMDFCLGLSIPGIVDSKNQKILSDSGISETNIDIQDYFKKFKNIIKLSIENDAKSAAYG
CCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHEEEEECCCCCCCCCC
EFYFGQDQKPINMVHLTFGTGLGCGIIINKEIYRTINHKAGEIGKSYSNINSTESVVVMD
CEEECCCCCCEEEEEEEECCCCCEEEEECHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEE
TSVIAILIKYKMATGKEISGKEFFELYEKKDPLVQKLMKDTSAVARTIIGLDYSFDFDLL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
TIGGGVSDNKIFQKLLFEELDLNKDFEFMGNKLSSNGQTISKVKISNLKNDAGCYGMLAI
EECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEEEEEEECCCCCCCCHHEEEEE
LKQN
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA