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The map label for this gene is zupT [H]

Identifier: 50086582

GI number: 50086582

Start: 3552064

End: 3552885

Strand: Reverse

Name: zupT [H]

Synonym: ACIAD3639

Alternate gene names: 50086582

Gene position: 3552885-3552064 (Counterclockwise)

Preceding gene: 50086583

Following gene: 50086579

Centisome position: 98.73

GC content: 43.92

Gene sequence:

>822_bases
TTGAGAATTTCCTGCATGTCTTCGTTCCTGACCTCTGATGTGCTGATTGCGTTTAGCGTAACCTTTCTAGCAGGATTGGC
GACATTACTGGGTGGAGCGATTGTTCTATTCTTTAAGCAACCCAGTTTGCGGTTATTGTCTTTTGGCCTAGCTTTTTCTG
CGGGTGCGATGGTCTATATTTCTCTCACTGAAATCTTAAATAAATCGATTCATTCTTTTTCAGAAGTTTTTAGTGCAAAA
GTGGGCTTTGCTTTCGCTACCTTTGCATTTTTGACTGGCGTCATTGCCATATTATTACTTGATCGTTGCGTGCCCAATCC
GCATACAATGCTGGAAAAAACCACAGCACAACAGCTCGATCAAACCCAGCTCCGACGTACAGGTTTACTGACGATGTTGG
CAATTACTGCACATAACTTTCCTGAAGGTCTGGCTACATTTTTTGCAACATTGGATAGCCCAATTTTGGGTGCACCTCTG
GCTGTCGCAATTGCAATTCATAATATTCCAGAAGGCATTGCAATTGCTGTTCCAGTATATATGGCAACAGGTCAAAAATC
GTATGCGATCTGGGCCAGTCTGCTGTCAGGCCTAGCTGAACCGTTGGGTGCGGCGCTTGGCTATTTTATTTTAGCCCCGT
ACATGGGAGCGACCATGTATGGCATTATTTTTGGATTAATTGCAGGAGTGATGGTTTATTTGGCCATGGATGAATTATTA
CCCGCCGCTAAAAAATACAGTCAGGGACATGAAACCGTATATGGGCTGGTTACAGGTATGGCTGCATTGGCGACTAGTTT
AGTCCTGTTTCAATGGGTATAG

Upstream 100 bases:

>100_bases
GAGGTAAAGGATCAACATACCCTATAAAAGCCAGGCAAATTGATTTTAAGATATTATTGAAAATGAAAGTCATTATCATT
TATGATGGTGGCTTTATTTT

Downstream 100 bases:

>100_bases
CACAGAAAAATCTAACCATAAAAAAAGCCGCATTATGCGACTTTTTCGATACGACAATAATAAAAACCATCGCCTTGACC
TGAGACTGGTAGTAACTGAC

Product: zinc transporter ZupT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MRISCMSSFLTSDVLIAFSVTFLAGLATLLGGAIVLFFKQPSLRLLSFGLAFSAGAMVYISLTEILNKSIHSFSEVFSAK
VGFAFATFAFLTGVIAILLLDRCVPNPHTMLEKTTAQQLDQTQLRRTGLLTMLAITAHNFPEGLATFFATLDSPILGAPL
AVAIAIHNIPEGIAIAVPVYMATGQKSYAIWASLLSGLAEPLGAALGYFILAPYMGATMYGIIFGLIAGVMVYLAMDELL
PAAKKYSQGHETVYGLVTGMAALATSLVLFQWV

Sequences:

>Translated_273_residues
MRISCMSSFLTSDVLIAFSVTFLAGLATLLGGAIVLFFKQPSLRLLSFGLAFSAGAMVYISLTEILNKSIHSFSEVFSAK
VGFAFATFAFLTGVIAILLLDRCVPNPHTMLEKTTAQQLDQTQLRRTGLLTMLAITAHNFPEGLATFFATLDSPILGAPL
AVAIAIHNIPEGIAIAVPVYMATGQKSYAIWASLLSGLAEPLGAALGYFILAPYMGATMYGIIFGLIAGVMVYLAMDELL
PAAKKYSQGHETVYGLVTGMAALATSLVLFQWV
>Mature_273_residues
MRISCMSSFLTSDVLIAFSVTFLAGLATLLGGAIVLFFKQPSLRLLSFGLAFSAGAMVYISLTEILNKSIHSFSEVFSAK
VGFAFATFAFLTGVIAILLLDRCVPNPHTMLEKTTAQQLDQTQLRRTGLLTMLAITAHNFPEGLATFFATLDSPILGAPL
AVAIAIHNIPEGIAIAVPVYMATGQKSYAIWASLLSGLAEPLGAALGYFILAPYMGATMYGIIFGLIAGVMVYLAMDELL
PAAKKYSQGHETVYGLVTGMAALATSLVLFQWV

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI229577422, Length=167, Percent_Identity=34.1317365269461, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI229577418, Length=167, Percent_Identity=34.1317365269461, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789419, Length=253, Percent_Identity=40.7114624505929, Blast_Score=161, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17507805, Length=306, Percent_Identity=26.797385620915, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24652846, Length=216, Percent_Identity=28.7037037037037, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 29048; Mature: 29048

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRISCMSSFLTSDVLIAFSVTFLAGLATLLGGAIVLFFKQPSLRLLSFGLAFSAGAMVYI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCHHHEE
SLTEILNKSIHSFSEVFSAKVGFAFATFAFLTGVIAILLLDRCVPNPHTMLEKTTAQQLD
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QTQLRRTGLLTMLAITAHNFPEGLATFFATLDSPILGAPLAVAIAIHNIPEGIAIAVPVY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEHHH
MATGQKSYAIWASLLSGLAEPLGAALGYFILAPYMGATMYGIIFGLIAGVMVYLAMDELL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PAAKKYSQGHETVYGLVTGMAALATSLVLFQWV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRISCMSSFLTSDVLIAFSVTFLAGLATLLGGAIVLFFKQPSLRLLSFGLAFSAGAMVYI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCHHHEE
SLTEILNKSIHSFSEVFSAKVGFAFATFAFLTGVIAILLLDRCVPNPHTMLEKTTAQQLD
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QTQLRRTGLLTMLAITAHNFPEGLATFFATLDSPILGAPLAVAIAIHNIPEGIAIAVPVY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEHHH
MATGQKSYAIWASLLSGLAEPLGAALGYFILAPYMGATMYGIIFGLIAGVMVYLAMDELL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PAAKKYSQGHETVYGLVTGMAALATSLVLFQWV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]