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The map label for this gene is dapB

Identifier: 50086567

GI number: 50086567

Start: 3530801

End: 3531622

Strand: Reverse

Name: dapB

Synonym: ACIAD3619

Alternate gene names: 50086567

Gene position: 3531622-3530801 (Counterclockwise)

Preceding gene: 50086568

Following gene: 50086566

Centisome position: 98.14

GC content: 49.03

Gene sequence:

>822_bases
ATGTCAGCATCTCCACGCATTGGTGTTTTGGGTGCGGGTGGCCGTATGGGTCGCATTCTTATTCAGGCTGTCCAACAGGC
AGGCTATCAATTGGCCGCTGCGGTAGAGCGTCCAGAAAGTAGCTTGGTAGGAAGCGATGCTGGCGAGCTGGCAGGGATCG
GTCACATCGGTGTCAAGATTTCAGGCAGTCTGGTAGAGGTTTTAAAAGATTGTGATGTAGTGATTGATTTCACTGCACCT
GTTGCAACTGAACAGCACCTTAAGCTTTGTGGTGATGCGGGTGTGGCGATGGTGATTGGCACGACAGGTTTCTCAGAACA
ACAAAAGCAGCTTTTAAACGAGACGGCACACCAAACCCCAGTCGTCTATGCCGCAAACTATTCTGTGGGTGTCAATGTCA
CGATCAAGTTGCTTGAACTTGCGTCAAAAGTGTTTGGGGATAGTGTCGACATTGAAATTATTGAAGCACACCATCGTCAT
AAAGTGGATGCGCCATCTGGGACAGCACTCATGATGGGTGAGGCAATTGCTGAAACACTTGGGCGTGATCTTAAACAAGA
TGCCGTTTACTGCCGTGAAGGTCATACAGGCCCACGAGAGCGTCAGAGTATCGGTTTCCAGACCATTCGTGGTGGAGATA
TTGTGGGTGAACACACGGCGATGTTTATTGGTGAAGGAGAGCGTGTCGAAATTACTCATAAAGCCACCAACCGTATGAAT
TTTGCTGCGGGCGCAGTACGTGCAGCGGCATGGGTGGTTGGGCGTGAAGCGCGTAAATATGACATGAAAGATGTTTTAGG
CTTTAACGATATTCAGGTTTAA

Upstream 100 bases:

>100_bases
CTGCTGCGGCAGGTTTTTTTATGGTGATTATTTTAGCGTCGAGCCTGAGTTTTGATATAGTAGAACACGAGTTTGGTCAT
TTTTATTTAGGATTTAGATT

Downstream 100 bases:

>100_bases
GCTGATCTCTGTATCAAAATAAATCAGCATGGCTGATATGCCAAACAGGTTGGGCTCTCTTGCCTGTTTGGTGTCCATAG
AAAAATAAAGCGTCTAAAAA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSASPRIGVLGAGGRMGRILIQAVQQAGYQLAAAVERPESSLVGSDAGELAGIGHIGVKISGSLVEVLKDCDVVIDFTAP
VATEQHLKLCGDAGVAMVIGTTGFSEQQKQLLNETAHQTPVVYAANYSVGVNVTIKLLELASKVFGDSVDIEIIEAHHRH
KVDAPSGTALMMGEAIAETLGRDLKQDAVYCREGHTGPRERQSIGFQTIRGGDIVGEHTAMFIGEGERVEITHKATNRMN
FAAGAVRAAAWVVGREARKYDMKDVLGFNDIQV

Sequences:

>Translated_273_residues
MSASPRIGVLGAGGRMGRILIQAVQQAGYQLAAAVERPESSLVGSDAGELAGIGHIGVKISGSLVEVLKDCDVVIDFTAP
VATEQHLKLCGDAGVAMVIGTTGFSEQQKQLLNETAHQTPVVYAANYSVGVNVTIKLLELASKVFGDSVDIEIIEAHHRH
KVDAPSGTALMMGEAIAETLGRDLKQDAVYCREGHTGPRERQSIGFQTIRGGDIVGEHTAMFIGEGERVEITHKATNRMN
FAAGAVRAAAWVVGREARKYDMKDVLGFNDIQV
>Mature_272_residues
SASPRIGVLGAGGRMGRILIQAVQQAGYQLAAAVERPESSLVGSDAGELAGIGHIGVKISGSLVEVLKDCDVVIDFTAPV
ATEQHLKLCGDAGVAMVIGTTGFSEQQKQLLNETAHQTPVVYAANYSVGVNVTIKLLELASKVFGDSVDIEIIEAHHRHK
VDAPSGTALMMGEAIAETLGRDLKQDAVYCREGHTGPRERQSIGFQTIRGGDIVGEHTAMFIGEGERVEITHKATNRMNF
AAGAVRAAAWVVGREARKYDMKDVLGFNDIQV

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=270, Percent_Identity=61.8518518518518, Blast_Score=314, Evalue=3e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_ACIAD (Q6F6R2)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_048077.1
- ProteinModelPortal:   Q6F6R2
- SMR:   Q6F6R2
- STRING:   Q6F6R2
- GeneID:   2878254
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD3619
- NMPDR:   fig|62977.3.peg.3270
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- PhylomeDB:   Q6F6R2
- ProtClustDB:   PRK00048
- BioCyc:   ASP62977:ACIAD3619-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 29004; Mature: 28873

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASPRIGVLGAGGRMGRILIQAVQQAGYQLAAAVERPESSLVGSDAGELAGIGHIGVKI
CCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEHHHHCCCHHCCCCCCHHHCCCEEEEEEE
SGSLVEVLKDCDVVIDFTAPVATEQHLKLCGDAGVAMVIGTTGFSEQQKQLLNETAHQTP
CHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCC
VVYAANYSVGVNVTIKLLELASKVFGDSVDIEIIEAHHRHKVDAPSGTALMMGEAIAETL
EEEEECCEECCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEHHHHHHHHHH
GRDLKQDAVYCREGHTGPRERQSIGFQTIRGGDIVGEHTAMFIGEGERVEITHKATNRMN
HHHHHHHHHHHHCCCCCCHHHHHCCCEEECCCCEECCCEEEEECCCCEEEEEECCCCCCH
FAAGAVRAAAWVVGREARKYDMKDVLGFNDIQV
HHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC
>Mature Secondary Structure 
SASPRIGVLGAGGRMGRILIQAVQQAGYQLAAAVERPESSLVGSDAGELAGIGHIGVKI
CCCCCEEEEECCCHHHHHHHHHHHHCCCEEEHHHHCCCHHCCCCCCHHHCCCEEEEEEE
SGSLVEVLKDCDVVIDFTAPVATEQHLKLCGDAGVAMVIGTTGFSEQQKQLLNETAHQTP
CHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCC
VVYAANYSVGVNVTIKLLELASKVFGDSVDIEIIEAHHRHKVDAPSGTALMMGEAIAETL
EEEEECCEECCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEHHHHHHHHHH
GRDLKQDAVYCREGHTGPRERQSIGFQTIRGGDIVGEHTAMFIGEGERVEITHKATNRMN
HHHHHHHHHHHHCCCCCCHHHHHCCCEEECCCCEECCCEEEEECCCCEEEEEECCCCCCH
FAAGAVRAAAWVVGREARKYDMKDVLGFNDIQV
HHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA