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The map label for this gene is ampC [H]

Identifier: 50086547

GI number: 50086547

Start: 3514986

End: 3516179

Strand: Reverse

Name: ampC [H]

Synonym: ACIAD3597

Alternate gene names: 50086547

Gene position: 3516179-3514986 (Counterclockwise)

Preceding gene: 50086548

Following gene: 50086546

Centisome position: 97.71

GC content: 43.72

Gene sequence:

>1194_bases
ATGATGAAAGACATATTAGGTAACTTAGATAACGTGCCATTTAAGATCATGACAGGCTGTATTGCAGGACTATTGTCCTG
TGGTACGGTCGCTCAATCGACAGTCCAACAATCAATTCAACAAAGTGTAGATCGACATTTTAAGCCCCTTATGGCTCAGT
ATCAAATTTCAGGAATGGCGATTGCGGTCAGCATAAATGGGCAACATTACTATCAGAATTATGGCGTAGCATCTAAACAG
ACCGAGCAAAATGTCTCTGAACATACTCTATTTGAGTTGGGTTCGGTGAGTAAGCTCTTTAATGCAACGCTGACGGGATA
TGCTCAAGCACAAGGTCAACTTAAGTTGAGTGATCATCCTGCCCAATATTTTCCAGAATTAAAAAATACAGCAGTGAATC
AGGCGACTCTCCTGAATCTGGGGACCTATACCGCAGGTGGTTTTCCGCTACAGTTTCCTGAGCAGATCAAGACAACACAA
GACATGACTCAGTATTTTCAGCACTGGCAGCCTAAAGCGGCTCCAAGACGTATTCGAGAATATTCAAATCCAAGCATTGG
CTTGATGGGCTATGTCACCGCACTTGCGATGAAAAATAGCTATTCAAATCTAATTGAAAATACGTTATTCCCTGCGTTGG
GGATGCATCATAGCTATATCAACGTTCCAGCAGCGCAGATGTCAAATTATGCATGGGGATATCAGGCAGATCAGGCGATA
CGTGTCTCACCAGGTATGTTTGATGCAGAGGCGTATGGCATCAAAAGTAACACTGCCGATATGCTTAAATTTCTAGATGC
TCAAATAAATCCCCAAAATCTAAAACCCACGCTCCGAAAGGCCATACAAACCACTCAGATGGGTTATTTTCGGGTGGGAC
AGATGCGACAGGGCTTGGGTTGGGAGCAATATACTTATCCAGTATCCTTAACAACCTTGCTGGCGGGAAATTCCGCTAAA
ATGGCTCTACAGCCTCAACCTGTTACAGGCATTTCAAAACCTATCACTGCTCCGCAGCAGGCCCTTTTGAATAAAACTGG
TGCAACCAATGGTTTTTCGGCTTATGTGGTGGTTATTCCGAGCCAAAAGATTGGACTGGTGATGCTTGCCAATCGTAATT
TTCCCAATGATGCACGGGTGAAAGCAGCTTATGCCACACTACAGCAAATCCTCAATGCAGATATTCAGAAATGA

Upstream 100 bases:

>100_bases
GGTTAATTACGGCCAATGATGGCAATATTTGGGTCATTCAAGATGGTCGCAATGGCAGCCTGATTCAATTAACCCCACAG
TAACGGATTAATCATTTTAA

Downstream 100 bases:

>100_bases
TTTATTTGATTGTAGATTCAAATTGTAGATTTGCATCAGACACAATAGACTACAGGAAAACACCATTAAGTCATTCGTAA
TGTCAGATACTCATATTCCA

Product: beta-lactamase

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MMKDILGNLDNVPFKIMTGCIAGLLSCGTVAQSTVQQSIQQSVDRHFKPLMAQYQISGMAIAVSINGQHYYQNYGVASKQ
TEQNVSEHTLFELGSVSKLFNATLTGYAQAQGQLKLSDHPAQYFPELKNTAVNQATLLNLGTYTAGGFPLQFPEQIKTTQ
DMTQYFQHWQPKAAPRRIREYSNPSIGLMGYVTALAMKNSYSNLIENTLFPALGMHHSYINVPAAQMSNYAWGYQADQAI
RVSPGMFDAEAYGIKSNTADMLKFLDAQINPQNLKPTLRKAIQTTQMGYFRVGQMRQGLGWEQYTYPVSLTTLLAGNSAK
MALQPQPVTGISKPITAPQQALLNKTGATNGFSAYVVVIPSQKIGLVMLANRNFPNDARVKAAYATLQQILNADIQK

Sequences:

>Translated_397_residues
MMKDILGNLDNVPFKIMTGCIAGLLSCGTVAQSTVQQSIQQSVDRHFKPLMAQYQISGMAIAVSINGQHYYQNYGVASKQ
TEQNVSEHTLFELGSVSKLFNATLTGYAQAQGQLKLSDHPAQYFPELKNTAVNQATLLNLGTYTAGGFPLQFPEQIKTTQ
DMTQYFQHWQPKAAPRRIREYSNPSIGLMGYVTALAMKNSYSNLIENTLFPALGMHHSYINVPAAQMSNYAWGYQADQAI
RVSPGMFDAEAYGIKSNTADMLKFLDAQINPQNLKPTLRKAIQTTQMGYFRVGQMRQGLGWEQYTYPVSLTTLLAGNSAK
MALQPQPVTGISKPITAPQQALLNKTGATNGFSAYVVVIPSQKIGLVMLANRNFPNDARVKAAYATLQQILNADIQK
>Mature_397_residues
MMKDILGNLDNVPFKIMTGCIAGLLSCGTVAQSTVQQSIQQSVDRHFKPLMAQYQISGMAIAVSINGQHYYQNYGVASKQ
TEQNVSEHTLFELGSVSKLFNATLTGYAQAQGQLKLSDHPAQYFPELKNTAVNQATLLNLGTYTAGGFPLQFPEQIKTTQ
DMTQYFQHWQPKAAPRRIREYSNPSIGLMGYVTALAMKNSYSNLIENTLFPALGMHHSYINVPAAQMSNYAWGYQADQAI
RVSPGMFDAEAYGIKSNTADMLKFLDAQINPQNLKPTLRKAIQTTQMGYFRVGQMRQGLGWEQYTYPVSLTTLLAGNSAK
MALQPQPVTGISKPITAPQQALLNKTGATNGFSAYVVVIPSQKIGLVMLANRNFPNDARVKAAYATLQQILNADIQK

Specific function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=384, Percent_Identity=44.53125, Blast_Score=325, Evalue=3e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 43716; Mature: 43716

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00336 BETA_LACTAMASE_C

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKDILGNLDNVPFKIMTGCIAGLLSCGTVAQSTVQQSIQQSVDRHFKPLMAQYQISGMA
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEE
IAVSINGQHYYQNYGVASKQTEQNVSEHTLFELGSVSKLFNATLTGYAQAQGQLKLSDHP
EEEEECCCEEECCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
AQYFPELKNTAVNQATLLNLGTYTAGGFPLQFPEQIKTTQDMTQYFQHWQPKAAPRRIRE
HHHHHHHHHHHCCHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YSNPSIGLMGYVTALAMKNSYSNLIENTLFPALGMHHSYINVPAAQMSNYAWGYQADQAI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHCCCCCCCCCCCEE
RVSPGMFDAEAYGIKSNTADMLKFLDAQINPQNLKPTLRKAIQTTQMGYFRVGQMRQGLG
EECCCCCCCHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCC
WEQYTYPVSLTTLLAGNSAKMALQPQPVTGISKPITAPQQALLNKTGATNGFSAYVVVIP
CCCEEECEEEEEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEC
SQKIGLVMLANRNFPNDARVKAAYATLQQILNADIQK
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMKDILGNLDNVPFKIMTGCIAGLLSCGTVAQSTVQQSIQQSVDRHFKPLMAQYQISGMA
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEE
IAVSINGQHYYQNYGVASKQTEQNVSEHTLFELGSVSKLFNATLTGYAQAQGQLKLSDHP
EEEEECCCEEECCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCC
AQYFPELKNTAVNQATLLNLGTYTAGGFPLQFPEQIKTTQDMTQYFQHWQPKAAPRRIRE
HHHHHHHHHHHCCHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YSNPSIGLMGYVTALAMKNSYSNLIENTLFPALGMHHSYINVPAAQMSNYAWGYQADQAI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHCCCCCCCCCCCEE
RVSPGMFDAEAYGIKSNTADMLKFLDAQINPQNLKPTLRKAIQTTQMGYFRVGQMRQGLG
EECCCCCCCHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCC
WEQYTYPVSLTTLLAGNSAKMALQPQPVTGISKPITAPQQALLNKTGATNGFSAYVVVIP
CCCEEECEEEEEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEC
SQKIGLVMLANRNFPNDARVKAAYATLQQILNADIQK
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA