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The map label for this gene is pgpA [H]

Identifier: 50086527

GI number: 50086527

Start: 3496289

End: 3496789

Strand: Direct

Name: pgpA [H]

Synonym: ACIAD3574

Alternate gene names: 50086527

Gene position: 3496289-3496789 (Clockwise)

Preceding gene: 50086526

Following gene: 50086528

Centisome position: 97.16

GC content: 42.91

Gene sequence:

>501_bases
TTGCCTAAACCACCGATCAATTTTCAACAGATGTCTTGGTCAGATCGCTGCATTGTTTTTTGTGGTGTAGGATTTGGTTC
AGGTTTATTACCCAAAGCACCTGGAACCTTTGGTTCTGCTTTTGCGTTGTTATTTATTCCATTCTGGGTCTGGGCTGGAT
TTTATCCAAGTGTCCTGATGATTTTGATGATGAGTCTTGTAGGCATTTACATCTGTGGTAAAGCAGCCAAGCTTATGGGC
GTGCATGATGATGGACGGATCGTGTGGGATGAATTTGCAGGACAATCGATTACCGTTCTGCCTTTAATCTATTTTAATCT
TATGGATGTAAAATGGGCCCTCATCAGTTTTGCCTTGTTCAGACTTTTTGATGTCTGGAAGCCTTGGCCTATTCGGGTGA
TTGATCGTCAGGTGCATGGTGGCTTTGGCATCATGCTCGACGATATTATCGCTGGATTGTGGGCCGCACTGTGTATTTTG
ATATATTTATCTCTGGTCTAA

Upstream 100 bases:

>100_bases
ATTAGCATCACAAAAATTGGCGAAATCACAGCACAACAAGATTTATCATTTGAATATCAGGGTCAGGATTACCCATTGCA
GCTTAAGGGATACCAACACT

Downstream 100 bases:

>100_bases
ACCGTTAAGTAGGTTATTCATGACAACGACCGTTATTATTCTTGCTGCTGGTAAAGGAACGCGCATGCGTTCCCATCTTC
CTAAAGTTTTGCAACCACTG

Product: phosphatidylglycerophosphatase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MPKPPINFQQMSWSDRCIVFCGVGFGSGLLPKAPGTFGSAFALLFIPFWVWAGFYPSVLMILMMSLVGIYICGKAAKLMG
VHDDGRIVWDEFAGQSITVLPLIYFNLMDVKWALISFALFRLFDVWKPWPIRVIDRQVHGGFGIMLDDIIAGLWAALCIL
IYLSLV

Sequences:

>Translated_166_residues
MPKPPINFQQMSWSDRCIVFCGVGFGSGLLPKAPGTFGSAFALLFIPFWVWAGFYPSVLMILMMSLVGIYICGKAAKLMG
VHDDGRIVWDEFAGQSITVLPLIYFNLMDVKWALISFALFRLFDVWKPWPIRVIDRQVHGGFGIMLDDIIAGLWAALCIL
IYLSLV
>Mature_165_residues
PKPPINFQQMSWSDRCIVFCGVGFGSGLLPKAPGTFGSAFALLFIPFWVWAGFYPSVLMILMMSLVGIYICGKAAKLMGV
HDDGRIVWDEFAGQSITVLPLIYFNLMDVKWALISFALFRLFDVWKPWPIRVIDRQVHGGFGIMLDDIIAGLWAALCILI
YLSLV

Specific function: One of the three phospholipid phosphatases, specifically hydrolyzes phosphatidylglycerophosphate [H]

COG id: COG1267

COG function: function code I; Phosphatidylglycerophosphatase A and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786620, Length=137, Percent_Identity=52.5547445255474, Blast_Score=126, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007686 [H]

Pfam domain/function: PF04608 PgpA [H]

EC number: =3.1.3.27 [H]

Molecular weight: Translated: 18612; Mature: 18480

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKPPINFQQMSWSDRCIVFCGVGFGSGLLPKAPGTFGSAFALLFIPFWVWAGFYPSVLM
CCCCCCCHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ILMMSLVGIYICGKAAKLMGVHDDGRIVWDEFAGQSITVLPLIYFNLMDVKWALISFALF
HHHHHHHHHHHHCCHHHHEECCCCCCEEEHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHH
RLFDVWKPWPIRVIDRQVHGGFGIMLDDIIAGLWAALCILIYLSLV
HHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PKPPINFQQMSWSDRCIVFCGVGFGSGLLPKAPGTFGSAFALLFIPFWVWAGFYPSVLM
CCCCCCHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ILMMSLVGIYICGKAAKLMGVHDDGRIVWDEFAGQSITVLPLIYFNLMDVKWALISFALF
HHHHHHHHHHHHCCHHHHEECCCCCCEEEHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHH
RLFDVWKPWPIRVIDRQVHGGFGIMLDDIIAGLWAALCILIYLSLV
HHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2846510; 9278503 [H]