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The map label for this gene is serB [H]

Identifier: 50086521

GI number: 50086521

Start: 3490419

End: 3491639

Strand: Reverse

Name: serB [H]

Synonym: ACIAD3567

Alternate gene names: 50086521

Gene position: 3491639-3490419 (Counterclockwise)

Preceding gene: 50086535

Following gene: 50086519

Centisome position: 97.03

GC content: 47.42

Gene sequence:

>1221_bases
ATGCGAGAAATCATTCTTATCTCTTTTTTGGGACCCGACCAACCTAATCAGTTCACCCGATTAATGCAGGTTTTGTCCGT
TCATTCCTTACAAATTCTAGATGTCGGTCAGGCAGTCATTCACAATCAGCTTACCTTGGGCATCGTGGTTGCATCCGACG
ACGAAACCGCTACAGCACTAGCGATGAAGGAAATTTTGATTCTAGCACATGATATCGGCCTCACTGTGCGCTTTAAACCG
ATCTCAAGTGCAGAATACGATCAGTGGGTCAGTGAGGGCGGACGTACACGCTATATTGTGACAGCATTAGCGCCAGAATT
GACCGCTTCACATTTACAAGCTGTTACCAAAATTGTCTCTAATCAAGGCTTCAATATTGAAACGGTAACCCGTTTATCGG
GTCGACCAGCACTTGAGTTGGAGCAAGATGCACCTCAGCGTGCCTGTGTGCAGTTTGGTTTAAGTGGACAAATGCTCGAT
GCACAGGCGATGCGTGCCGCATGCTTAAGCCTCTCTGGTGAACTGAACATTGATGTGGCTGTGCAAGAAGACAACGCTTA
CCGTCGTAATCGTCGTTTGGTCTGTTTTGATATGGACTCGACCCTGATCGAGCAAGAGGTGATTGATGAGCTAGCACTTG
AAGCAGGTGTTGGTGAGCAAGTTGCCGAAATCACCGAACGTGCCATGCAGGGCGAGCTGGATTTTCAGCAAAGTTTTCGC
GCACGTGTGGCATTGCTTAAAGGTCTTGATGCCGCTGTGTTACCTAAAATTGCCGAGCGTCTCACCGTAACGGAAGGTGC
AGAGCGTTTGATTTCTACTCTAAAAGCATTGGGTTATCGTACAGCAATCTTATCGGGCGGTTTTCAATATTTTGCAGAAT
ATTTACAAGGTAAACTCGGGATTGATGAAGTCCATGCCAATATTCTGGATGTCGAAAATGGCTTCGTCACTGGTGAAGTG
AAAGGTGCGATTGTCGATGGTGCGCGTAAGGCAGAATTACTACGTGATCTGGCACAGTGTATGGGAATTTCACTCGAACA
GACCATCGCGGTAGGTGACGGTGCCAATGATCTACCAATGCTGTCGATTGCTGGTTTAGGCGTGGCATTTCGTGCTAAAC
CGCTGGTGCGTCAGAATGCCAATCAGGCAATTTCCAGTGTTGGTTTAGATGGCGTACTGTATCTGCTCGGGGTACATGAT
AAAGACTTGTCTCGTGCTTGA

Upstream 100 bases:

>100_bases
AGCCCTTGTCGAGGTGCATTCAACGTAAACTTCCAAGGCAAATAGATTCAAATTCGATTATGATTCTTACAATAGTTGTA
GCTCAAACCCGAGTCAATTC

Downstream 100 bases:

>100_bases
TATAATCTCTCATGATGTAAAAACGCCATGATCTTATGGCGTTTTTTTATGTTTAATTTTAAAAGAATCAATGGCTTTTG
TTCGCTAAAAAAAATGATAA

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MREIILISFLGPDQPNQFTRLMQVLSVHSLQILDVGQAVIHNQLTLGIVVASDDETATALAMKEILILAHDIGLTVRFKP
ISSAEYDQWVSEGGRTRYIVTALAPELTASHLQAVTKIVSNQGFNIETVTRLSGRPALELEQDAPQRACVQFGLSGQMLD
AQAMRAACLSLSGELNIDVAVQEDNAYRRNRRLVCFDMDSTLIEQEVIDELALEAGVGEQVAEITERAMQGELDFQQSFR
ARVALLKGLDAAVLPKIAERLTVTEGAERLISTLKALGYRTAILSGGFQYFAEYLQGKLGIDEVHANILDVENGFVTGEV
KGAIVDGARKAELLRDLAQCMGISLEQTIAVGDGANDLPMLSIAGLGVAFRAKPLVRQNANQAISSVGLDGVLYLLGVHD
KDLSRA

Sequences:

>Translated_406_residues
MREIILISFLGPDQPNQFTRLMQVLSVHSLQILDVGQAVIHNQLTLGIVVASDDETATALAMKEILILAHDIGLTVRFKP
ISSAEYDQWVSEGGRTRYIVTALAPELTASHLQAVTKIVSNQGFNIETVTRLSGRPALELEQDAPQRACVQFGLSGQMLD
AQAMRAACLSLSGELNIDVAVQEDNAYRRNRRLVCFDMDSTLIEQEVIDELALEAGVGEQVAEITERAMQGELDFQQSFR
ARVALLKGLDAAVLPKIAERLTVTEGAERLISTLKALGYRTAILSGGFQYFAEYLQGKLGIDEVHANILDVENGFVTGEV
KGAIVDGARKAELLRDLAQCMGISLEQTIAVGDGANDLPMLSIAGLGVAFRAKPLVRQNANQAISSVGLDGVLYLLGVHD
KDLSRA
>Mature_406_residues
MREIILISFLGPDQPNQFTRLMQVLSVHSLQILDVGQAVIHNQLTLGIVVASDDETATALAMKEILILAHDIGLTVRFKP
ISSAEYDQWVSEGGRTRYIVTALAPELTASHLQAVTKIVSNQGFNIETVTRLSGRPALELEQDAPQRACVQFGLSGQMLD
AQAMRAACLSLSGELNIDVAVQEDNAYRRNRRLVCFDMDSTLIEQEVIDELALEAGVGEQVAEITERAMQGELDFQQSFR
ARVALLKGLDAAVLPKIAERLTVTEGAERLISTLKALGYRTAILSGGFQYFAEYLQGKLGIDEVHANILDVENGFVTGEV
KGAIVDGARKAELLRDLAQCMGISLEQTIAVGDGANDLPMLSIAGLGVAFRAKPLVRQNANQAISSVGLDGVLYLLGVHD
KDLSRA

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=203, Percent_Identity=32.0197044334975, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1790849, Length=236, Percent_Identity=48.728813559322, Blast_Score=203, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI115534456, Length=191, Percent_Identity=30.8900523560209, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115534454, Length=191, Percent_Identity=30.8900523560209, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321647, Length=230, Percent_Identity=45.2173913043478, Blast_Score=193, Evalue=5e-50,
Organism=Drosophila melanogaster, GI24661601, Length=184, Percent_Identity=32.0652173913043, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 43953; Mature: 43953

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIILISFLGPDQPNQFTRLMQVLSVHSLQILDVGQAVIHNQLTLGIVVASDDETATAL
CCEEEEEEECCCCCCHHHHHHHHHHHHHCEEEEHHHHHHHHCCEEEEEEEECCCCHHHHH
AMKEILILAHDIGLTVRFKPISSAEYDQWVSEGGRTRYIVTALAPELTASHLQAVTKIVS
HHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHH
NQGFNIETVTRLSGRPALELEQDAPQRACVQFGLSGQMLDAQAMRAACLSLSGELNIDVA
CCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCEECHHHHHHHHHHCCCCCEEEEE
VQEDNAYRRNRRLVCFDMDSTLIEQEVIDELALEAGVGEQVAEITERAMQGELDFQQSFR
EECCCCHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHH
ARVALLKGLDAAVLPKIAERLTVTEGAERLISTLKALGYRTAILSGGFQYFAEYLQGKLG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
IDEVHANILDVENGFVTGEVKGAIVDGARKAELLRDLAQCMGISLEQTIAVGDGANDLPM
HHHHHHHHEECCCCEEEEEECEEEECCHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCE
LSIAGLGVAFRAKPLVRQNANQAISSVGLDGVLYLLGVHDKDLSRA
EEECCCCHHHCCCHHHHCCHHHHHHHCCCCCEEEEEECCCHHCCCC
>Mature Secondary Structure
MREIILISFLGPDQPNQFTRLMQVLSVHSLQILDVGQAVIHNQLTLGIVVASDDETATAL
CCEEEEEEECCCCCCHHHHHHHHHHHHHCEEEEHHHHHHHHCCEEEEEEEECCCCHHHHH
AMKEILILAHDIGLTVRFKPISSAEYDQWVSEGGRTRYIVTALAPELTASHLQAVTKIVS
HHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHH
NQGFNIETVTRLSGRPALELEQDAPQRACVQFGLSGQMLDAQAMRAACLSLSGELNIDVA
CCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCEECHHHHHHHHHHCCCCCEEEEE
VQEDNAYRRNRRLVCFDMDSTLIEQEVIDELALEAGVGEQVAEITERAMQGELDFQQSFR
EECCCCHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHH
ARVALLKGLDAAVLPKIAERLTVTEGAERLISTLKALGYRTAILSGGFQYFAEYLQGKLG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
IDEVHANILDVENGFVTGEVKGAIVDGARKAELLRDLAQCMGISLEQTIAVGDGANDLPM
HHHHHHHHEECCCCEEEEEECEEEECCHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCE
LSIAGLGVAFRAKPLVRQNANQAISSVGLDGVLYLLGVHDKDLSRA
EEECCCCHHHCCCHHHHCCHHHHHHHCCCCCEEEEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA