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The map label for this gene is alc

Identifier: 50086496

GI number: 50086496

Start: 3466513

End: 3467517

Strand: Direct

Name: alc

Synonym: ACIAD3541

Alternate gene names: 50086496

Gene position: 3466513-3467517 (Clockwise)

Preceding gene: 50086494

Following gene: 50086497

Centisome position: 96.33

GC content: 43.18

Gene sequence:

>1005_bases
ATGGCAACGCTTCTCGCACCAGCATTTGAACTCCCAACAAGCTTACATTCGCTAACCAATCTGGCAGATTCCAGAATTGG
TGCTCAAATTGTTGAATGTTCAGATGATTTTTTTGCAGAAGCAAAACGGATGCTGCAATTTGAGGCACCTATTTTTGTCG
AAGACAAATTTGATGACCATGGGAAATGGATGGATGGATGGGAAACCCGTCGTAAACGCCATGCAGGTTACGATTGGTGC
ATTGTGAAGTTAGGTGTTGCAGGCAAGATTAAAGCTGTAGATATCGATACCACTTTTTTCACAGGTAACTATCCCGCTTC
TGCATCATTAGAGGGCTGCTATGCACCAAATGGGAACACTCAAGAAGCTTTATGGCAACCATTATTGGGCAACTCAATTC
TGGGACCAAGTCAACATCATGTTTTTGATGTTCAAAATGATGCCATTTTTACTCATATTCGCCTTAACATTTTTCCTGAT
GGTGGTGTGGCACGTTTACGTATCTATGGTGATGTACAAATTCAGATCACAGATACAGATCAAACCCTTGATCTATTGGC
ACTACAAAATGGTGGACGTGTAATCGCTTATAGTGATGCACACTTTGGCCATCCTCGTAACCTGATTAACCCTGGACGTG
GTGTGAATATGGGAGACGGCTGGGAAACCAAACGTCGCCGTGCGCCAGGCTTCGACTGGTGTTTATTGGCACTTGGACAA
GCAGGCAAGATTGAAAAGATCGAGATTGATACTGCACACTTCAAGGGTAATTACCCAGCGCAAGTGTCGATTCAGGCAAT
TTATATTGAAGATGCCACGGATCCACAGTTGATTCCACAAAGTATGTTCTGGCCATTTTTGTTAGAGGCGCAAGATATGC
AGATGGATCATATTCACAGCTATCTAAATGAAGTTCTGGCTCATGAAAAAGTTTCACATATCCGCGTCAATATGATTCCC
GATGGTGGTATTAGCCGTGTTCGTTTATGGGGCAAAGTGGTTTAA

Upstream 100 bases:

>100_bases
AAGCACGATGATGATGCATTCTTACTGCATTTTGAGTTAAAAAGACACATCAACTCACATCAAGTTGTAATTTATTAATT
ATCTTTAACGGAAATATACA

Downstream 100 bases:

>100_bases
CACCGAGATTATATTATGCCAGATCGAATCATTCATATTCAGCCACTTACCGTTGAAAACTTTCAGCCTTTTGGGGAAGT
GATTAGCTGTACTGGCCATT

Product: allantoicase

Products: NA

Alternate protein names: Allantoate amidinohydrolase

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MATLLAPAFELPTSLHSLTNLADSRIGAQIVECSDDFFAEAKRMLQFEAPIFVEDKFDDHGKWMDGWETRRKRHAGYDWC
IVKLGVAGKIKAVDIDTTFFTGNYPASASLEGCYAPNGNTQEALWQPLLGNSILGPSQHHVFDVQNDAIFTHIRLNIFPD
GGVARLRIYGDVQIQITDTDQTLDLLALQNGGRVIAYSDAHFGHPRNLINPGRGVNMGDGWETKRRRAPGFDWCLLALGQ
AGKIEKIEIDTAHFKGNYPAQVSIQAIYIEDATDPQLIPQSMFWPFLLEAQDMQMDHIHSYLNEVLAHEKVSHIRVNMIP
DGGISRVRLWGKVV

Sequences:

>Translated_334_residues
MATLLAPAFELPTSLHSLTNLADSRIGAQIVECSDDFFAEAKRMLQFEAPIFVEDKFDDHGKWMDGWETRRKRHAGYDWC
IVKLGVAGKIKAVDIDTTFFTGNYPASASLEGCYAPNGNTQEALWQPLLGNSILGPSQHHVFDVQNDAIFTHIRLNIFPD
GGVARLRIYGDVQIQITDTDQTLDLLALQNGGRVIAYSDAHFGHPRNLINPGRGVNMGDGWETKRRRAPGFDWCLLALGQ
AGKIEKIEIDTAHFKGNYPAQVSIQAIYIEDATDPQLIPQSMFWPFLLEAQDMQMDHIHSYLNEVLAHEKVSHIRVNMIP
DGGISRVRLWGKVV
>Mature_333_residues
ATLLAPAFELPTSLHSLTNLADSRIGAQIVECSDDFFAEAKRMLQFEAPIFVEDKFDDHGKWMDGWETRRKRHAGYDWCI
VKLGVAGKIKAVDIDTTFFTGNYPASASLEGCYAPNGNTQEALWQPLLGNSILGPSQHHVFDVQNDAIFTHIRLNIFPDG
GVARLRIYGDVQIQITDTDQTLDLLALQNGGRVIAYSDAHFGHPRNLINPGRGVNMGDGWETKRRRAPGFDWCLLALGQA
GKIEKIEIDTAHFKGNYPAQVSIQAIYIEDATDPQLIPQSMFWPFLLEAQDMQMDHIHSYLNEVLAHEKVSHIRVNMIPD
GGISRVRLWGKVV

Specific function: Unknown

COG id: COG4266

COG function: function code F; Allantoicase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the allantoicase family

Homologues:

Organism=Homo sapiens, GI144953901, Length=364, Percent_Identity=35.1648351648352, Blast_Score=227, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6322220, Length=329, Percent_Identity=40.1215805471125, Blast_Score=236, Evalue=5e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALLC_ACIAD (Q6F6Y1)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_048006.1
- ProteinModelPortal:   Q6F6Y1
- SMR:   Q6F6Y1
- STRING:   Q6F6Y1
- GeneID:   2878213
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD3541
- NMPDR:   fig|62977.3.peg.3199
- eggNOG:   COG4266
- HOGENOM:   HBG480577
- OMA:   NSHHYHE
- PhylomeDB:   Q6F6Y1
- ProtClustDB:   PRK13257
- BioCyc:   ASP62977:ACIAD3541-MONOMER
- HAMAP:   MF_00813
- InterPro:   IPR005164
- InterPro:   IPR015908
- InterPro:   IPR008979
- PANTHER:   PTHR12045
- PIRSF:   PIRSF016516
- TIGRFAMs:   TIGR02961

Pfam domain/function: PF03561 Allantoicase; SSF49785 Gal_bind_like

EC number: =3.5.3.4

Molecular weight: Translated: 37396; Mature: 37265

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLLAPAFELPTSLHSLTNLADSRIGAQIVECSDDFFAEAKRMLQFEAPIFVEDKFDDH
CCCEECCHHHCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHEECCCEEEECCCCCC
GKWMDGWETRRKRHAGYDWCIVKLGVAGKIKAVDIDTTFFTGNYPASASLEGCYAPNGNT
CCCCCCHHHHHHHCCCCCEEEEEECCCCEEEEEEEEEEEEECCCCCCCCCCEEECCCCCC
QEALWQPLLGNSILGPSQHHVFDVQNDAIFTHIRLNIFPDGGVARLRIYGDVQIQITDTD
HHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEEEEEEECCCCEEEEEEEEEEEEEEECCC
QTLDLLALQNGGRVIAYSDAHFGHPRNLINPGRGVNMGDGWETKRRRAPGFDWCLLALGQ
CCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHEECCC
AGKIEKIEIDTAHFKGNYPAQVSIQAIYIEDATDPQLIPQSMFWPFLLEAQDMQMDHIHS
CCCEEEEEEEEEEECCCCCCEEEEEEEEEECCCCCCCCCHHHCCCEEECCCCCCHHHHHH
YLNEVLAHEKVSHIRVNMIPDGGISRVRLWGKVV
HHHHHHHHCCCCEEEEEEECCCCCCEEEEEEECC
>Mature Secondary Structure 
ATLLAPAFELPTSLHSLTNLADSRIGAQIVECSDDFFAEAKRMLQFEAPIFVEDKFDDH
CCEECCHHHCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHEECCCEEEECCCCCC
GKWMDGWETRRKRHAGYDWCIVKLGVAGKIKAVDIDTTFFTGNYPASASLEGCYAPNGNT
CCCCCCHHHHHHHCCCCCEEEEEECCCCEEEEEEEEEEEEECCCCCCCCCCEEECCCCCC
QEALWQPLLGNSILGPSQHHVFDVQNDAIFTHIRLNIFPDGGVARLRIYGDVQIQITDTD
HHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEEEEEEECCCCEEEEEEEEEEEEEEECCC
QTLDLLALQNGGRVIAYSDAHFGHPRNLINPGRGVNMGDGWETKRRRAPGFDWCLLALGQ
CCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHEECCC
AGKIEKIEIDTAHFKGNYPAQVSIQAIYIEDATDPQLIPQSMFWPFLLEAQDMQMDHIHS
CCCEEEEEEEEEEECCCCCCEEEEEEEEEECCCCCCCCCHHHCCCEEECCCCCCHHHHHH
YLNEVLAHEKVSHIRVNMIPDGGISRVRLWGKVV
HHHHHHHHCCCCEEEEEEECCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA