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The map label for this gene is argE [H]

Identifier: 50086450

GI number: 50086450

Start: 3416331

End: 3417470

Strand: Reverse

Name: argE [H]

Synonym: ACIAD3489

Alternate gene names: 50086450

Gene position: 3417470-3416331 (Counterclockwise)

Preceding gene: 50086451

Following gene: 50086449

Centisome position: 94.97

GC content: 41.32

Gene sequence:

>1140_bases
ATGAATAAGCAGATTAGAAGTTTAGCGTTATTGGAACGGTTGATTGCATTTGATACGACATCTTATAAAAGTAATATCGA
ACTGATTGATGATGTAAAGCAGATCTTTGAACAACATCAAATCTATGTGCAGCTTAACTTCAATCAGGACAGAACCAAAG
CCAACTTATTTGCCAGTACAGGCCCAGAAAATGAAGCTGGCATTTTACTTTCAGGGCATTCTGATGTGGTTCCAGTAACT
GGACAACAATGGGATACGCCTGCCTTTAATGCTGTGATTAAAGATGATCATGTGTATGGTCGTGGTACAGCAGATATGAA
AGGTTTTTTGGCCTGTGCCATCAATGCAATGTTGGATGCTTCACAGTGTCAGCTGAAAAGACCATTACAGTTATGTATTT
CTTATGATGAAGAAATTGGCTGTATTGGGGTAAGAGGAATTTTGGAACATTTATCCGAAAATTTAATACCTCCACTGGTG
TGTGTCATCGGTGAGCCAACCATGATGCAGATGGCACTTGCCCATAAAGGTAAAACCGTTTATCAGGCTCGTTGCTGTGG
TGAAGAGGGGCATTCTGCCTTGGCGCCACGTTTTGTCAACGCGATTCATGTCGCAGGTCACCTGATTCAATCCTTACAAC
AGACTCAGCAGTATATCGCGTTACAAGGCCAGCAGGATCAGGGTTACGACATCCCTTATACCACGATTCATGTGGGTAAA
ATTGCAGGTGGAACCGCTTTAAACATTGTTCCAAATCAATGCATTGTGGATTATGAAATTCGAAACTTGGCTGAGGACAG
TAGTACCAACATTCAAAATTTGATCTTTGACAAAATCAGTGAAGAATATCAATCCCATATTGAAATCAAGCAAGTCAATG
AATATCCAGGACTAAAAACATCACCGACTGTACAGGCGGTTGAGTTTATTCAGCAACTTCTTCCTGTTGATACGACACAG
ACCAATATTTCGTTTGGGACAGAAGGTGGGCTGTTTCAAAGTGCCATGAATTGTCCTGTGATTGTTTGTGGGCCAGGGGA
TATCGCGGTGGCTCACAAGCCAAATGAATATGTCTCACTGGCGCAGTTGCGACAATGTGAAATATTTTTAGAAAAATTAG
TGACCACTATTACGGTCTAA

Upstream 100 bases:

>100_bases
TGCTTTTATTTCCAATCATTATATTTCAGGCATGACCGATGCCCATTTCTTTGACCCACATATTAAATCTCATGCACTCG
ATGTTCAGGAACCTGAGTAG

Downstream 100 bases:

>100_bases
ATGATTAGCTCTGGATCATGCTGCCAGACAGCATGATCTTGCGGGACGCTCTATTTTCATCAATTCATTGTACAAATGTC
TTCATTTGAATATATCGGCA

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNKQIRSLALLERLIAFDTTSYKSNIELIDDVKQIFEQHQIYVQLNFNQDRTKANLFASTGPENEAGILLSGHSDVVPVT
GQQWDTPAFNAVIKDDHVYGRGTADMKGFLACAINAMLDASQCQLKRPLQLCISYDEEIGCIGVRGILEHLSENLIPPLV
CVIGEPTMMQMALAHKGKTVYQARCCGEEGHSALAPRFVNAIHVAGHLIQSLQQTQQYIALQGQQDQGYDIPYTTIHVGK
IAGGTALNIVPNQCIVDYEIRNLAEDSSTNIQNLIFDKISEEYQSHIEIKQVNEYPGLKTSPTVQAVEFIQQLLPVDTTQ
TNISFGTEGGLFQSAMNCPVIVCGPGDIAVAHKPNEYVSLAQLRQCEIFLEKLVTTITV

Sequences:

>Translated_379_residues
MNKQIRSLALLERLIAFDTTSYKSNIELIDDVKQIFEQHQIYVQLNFNQDRTKANLFASTGPENEAGILLSGHSDVVPVT
GQQWDTPAFNAVIKDDHVYGRGTADMKGFLACAINAMLDASQCQLKRPLQLCISYDEEIGCIGVRGILEHLSENLIPPLV
CVIGEPTMMQMALAHKGKTVYQARCCGEEGHSALAPRFVNAIHVAGHLIQSLQQTQQYIALQGQQDQGYDIPYTTIHVGK
IAGGTALNIVPNQCIVDYEIRNLAEDSSTNIQNLIFDKISEEYQSHIEIKQVNEYPGLKTSPTVQAVEFIQQLLPVDTTQ
TNISFGTEGGLFQSAMNCPVIVCGPGDIAVAHKPNEYVSLAQLRQCEIFLEKLVTTITV
>Mature_379_residues
MNKQIRSLALLERLIAFDTTSYKSNIELIDDVKQIFEQHQIYVQLNFNQDRTKANLFASTGPENEAGILLSGHSDVVPVT
GQQWDTPAFNAVIKDDHVYGRGTADMKGFLACAINAMLDASQCQLKRPLQLCISYDEEIGCIGVRGILEHLSENLIPPLV
CVIGEPTMMQMALAHKGKTVYQARCCGEEGHSALAPRFVNAIHVAGHLIQSLQQTQQYIALQGQQDQGYDIPYTTIHVGK
IAGGTALNIVPNQCIVDYEIRNLAEDSSTNIQNLIFDKISEEYQSHIEIKQVNEYPGLKTSPTVQAVEFIQQLLPVDTTQ
TNISFGTEGGLFQSAMNCPVIVCGPGDIAVAHKPNEYVSLAQLRQCEIFLEKLVTTITV

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=365, Percent_Identity=32.0547945205479, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1788816, Length=333, Percent_Identity=27.027027027027, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17551016, Length=343, Percent_Identity=26.530612244898, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 41805; Mature: 41805

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQIRSLALLERLIAFDTTSYKSNIELIDDVKQIFEQHQIYVQLNFNQDRTKANLFAST
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCHHEEEECC
GPENEAGILLSGHSDVVPVTGQQWDTPAFNAVIKDDHVYGRGTADMKGFLACAINAMLDA
CCCCCCCEEEECCCCEEECCCCCCCCCHHCEEEECCCEECCCCHHHHHHHHHHHHHHHCH
SQCQLKRPLQLCISYDEEIGCIGVRGILEHLSENLIPPLVCVIGEPTMMQMALAHKGKTV
HHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCEE
YQARCCGEEGHSALAPRFVNAIHVAGHLIQSLQQTQQYIALQGQQDQGYDIPYTTIHVGK
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEEEE
IAGGTALNIVPNQCIVDYEIRNLAEDSSTNIQNLIFDKISEEYQSHIEIKQVNEYPGLKT
CCCCEEEEECCCCEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCC
SPTVQAVEFIQQLLPVDTTQTNISFGTEGGLFQSAMNCPVIVCGPGDIAVAHKPNEYVSL
CCHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHCCCCEEEECCCCEEEEECCCHHHHH
AQLRQCEIFLEKLVTTITV
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKQIRSLALLERLIAFDTTSYKSNIELIDDVKQIFEQHQIYVQLNFNQDRTKANLFAST
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCHHEEEECC
GPENEAGILLSGHSDVVPVTGQQWDTPAFNAVIKDDHVYGRGTADMKGFLACAINAMLDA
CCCCCCCEEEECCCCEEECCCCCCCCCHHCEEEECCCEECCCCHHHHHHHHHHHHHHHCH
SQCQLKRPLQLCISYDEEIGCIGVRGILEHLSENLIPPLVCVIGEPTMMQMALAHKGKTV
HHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCEE
YQARCCGEEGHSALAPRFVNAIHVAGHLIQSLQQTQQYIALQGQQDQGYDIPYTTIHVGK
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEEEE
IAGGTALNIVPNQCIVDYEIRNLAEDSSTNIQNLIFDKISEEYQSHIEIKQVNEYPGLKT
CCCCEEEEECCCCEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCC
SPTVQAVEFIQQLLPVDTTQTNISFGTEGGLFQSAMNCPVIVCGPGDIAVAHKPNEYVSL
CCHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHCCCCEEEECCCCEEEEECCCHHHHH
AQLRQCEIFLEKLVTTITV
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9829957 [H]