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The map label for this gene is ompR [H]

Identifier: 50086362

GI number: 50086362

Start: 3301865

End: 3302629

Strand: Direct

Name: ompR [H]

Synonym: ACIAD3388

Alternate gene names: 50086362

Gene position: 3301865-3302629 (Clockwise)

Preceding gene: 50086359

Following gene: 50086363

Centisome position: 91.75

GC content: 46.01

Gene sequence:

>765_bases
ATGAGTTTAGTTGTACCTGCTGAACATACTGAAACTGTACATAACGAAACCGATCGTGTCGAACGTATTTTGGTCGTCGA
TGACGATGTGCGTTTACGCACCCTTTTACAACGCTTTTTAGAAGACAAAGGTTTTGTTGTAAAAACAGCGCATGATGCAA
CTCAAATGGATCGTTTGCTTCAGCGTGAATTATTTTCTTTGATTGTTTTAGATTTTATGCTTCCAGTGGAAGACGGTTTA
AGTATTTGTCGACGTCTACGTCAGTCGAATATCGACACGCCAATTATCATGCTGACTGCACGTGGCAGTGATTCAGACCG
TATTGCAGGACTTGAAGCAGGTGCCGATGATTACCTGCCAAAACCTTTCAATCCAAACGAATTACTAGCACGTATCCGCG
CGGTATTGCGTCGTCAGGTTCGTGAAGTACCAGGAGCGCCAAGCCAACAGGTCGAAGTGGTCAGCTTTGGATCGTGGGCA
CTTGATTTATCTACACGTACCTTGACACGTGAAGGTCAAGTTGTGACGCTTACAACAGGTGAGTTTGCTGTCTTAAAAGC
ACTGGTTCAGCATCCACGCGAGCCCCTGACCCGCGACAAGCTCATGAATCTGGCACGTGGTCGTGAATGGGGTGCCATGG
AACGATCTATTGATGTACAGGTTTCACGTTTACGCCGCCTGATTGAAGATAATCCAGCACGTGCTCGTTATATTCAAACT
GTGTGGGGAATTGGCTACGTGTTTGTTCCAGATGGTGCAGAATAA

Upstream 100 bases:

>100_bases
AATTTTGAGCAATTTGATACATAGTCTAAACAAGACTATCAGCATTATACTGCAGTGATCCAATAATCTATAAATATTGA
CTTAATAAAGGGAGTACATC

Downstream 100 bases:

>100_bases
TAAGTGCCCTAGGATAATCGTGTGAAGTTAGATCCCGTCGATTTACAGGCGTATACCGATTTTGTCGCTTACTCAGAACG
TAAGCGAACACGTTGGGAAC

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MSLVVPAEHTETVHNETDRVERILVVDDDVRLRTLLQRFLEDKGFVVKTAHDATQMDRLLQRELFSLIVLDFMLPVEDGL
SICRRLRQSNIDTPIIMLTARGSDSDRIAGLEAGADDYLPKPFNPNELLARIRAVLRRQVREVPGAPSQQVEVVSFGSWA
LDLSTRTLTREGQVVTLTTGEFAVLKALVQHPREPLTRDKLMNLARGREWGAMERSIDVQVSRLRRLIEDNPARARYIQT
VWGIGYVFVPDGAE

Sequences:

>Translated_254_residues
MSLVVPAEHTETVHNETDRVERILVVDDDVRLRTLLQRFLEDKGFVVKTAHDATQMDRLLQRELFSLIVLDFMLPVEDGL
SICRRLRQSNIDTPIIMLTARGSDSDRIAGLEAGADDYLPKPFNPNELLARIRAVLRRQVREVPGAPSQQVEVVSFGSWA
LDLSTRTLTREGQVVTLTTGEFAVLKALVQHPREPLTRDKLMNLARGREWGAMERSIDVQVSRLRRLIEDNPARARYIQT
VWGIGYVFVPDGAE
>Mature_253_residues
SLVVPAEHTETVHNETDRVERILVVDDDVRLRTLLQRFLEDKGFVVKTAHDATQMDRLLQRELFSLIVLDFMLPVEDGLS
ICRRLRQSNIDTPIIMLTARGSDSDRIAGLEAGADDYLPKPFNPNELLARIRAVLRRQVREVPGAPSQQVEVVSFGSWAL
DLSTRTLTREGQVVTLTTGEFAVLKALVQHPREPLTRDKLMNLARGREWGAMERSIDVQVSRLRRLIEDNPARARYIQTV
WGIGYVFVPDGAE

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=69.0987124463519, Blast_Score=340, Evalue=5e-95,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=39.8305084745763, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=36.2445414847162, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=38.7931034482759, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=34.8936170212766, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=36.7965367965368, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1788394, Length=238, Percent_Identity=33.1932773109244, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786911, Length=238, Percent_Identity=37.8151260504202, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=35.2173913043478, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI145693140, Length=240, Percent_Identity=32.5, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=34.2105263157895, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=32.3275862068966, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=30.3964757709251, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=31.2775330396476, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=30.0813008130081, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790437, Length=172, Percent_Identity=29.0697674418605, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788550, Length=179, Percent_Identity=26.2569832402235, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28808; Mature: 28676

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVVPAEHTETVHNETDRVERILVVDDDVRLRTLLQRFLEDKGFVVKTAHDATQMDRLL
CCEECCCCHHHHHHCHHHHHEEEEEECCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHH
QRELFSLIVLDFMLPVEDGLSICRRLRQSNIDTPIIMLTARGSDSDRIAGLEAGADDYLP
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCCCCCC
KPFNPNELLARIRAVLRRQVREVPGAPSQQVEVVSFGSWALDLSTRTLTREGQVVTLTTG
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEECCHHEEECCCCEEEEECC
EFAVLKALVQHPREPLTRDKLMNLARGREWGAMERSIDVQVSRLRRLIEDNPARARYIQT
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VWGIGYVFVPDGAE
HHCCCEEECCCCCC
>Mature Secondary Structure 
SLVVPAEHTETVHNETDRVERILVVDDDVRLRTLLQRFLEDKGFVVKTAHDATQMDRLL
CEECCCCHHHHHHCHHHHHEEEEEECCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHH
QRELFSLIVLDFMLPVEDGLSICRRLRQSNIDTPIIMLTARGSDSDRIAGLEAGADDYLP
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCCCCCC
KPFNPNELLARIRAVLRRQVREVPGAPSQQVEVVSFGSWALDLSTRTLTREGQVVTLTTG
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEECCHHEEECCCCEEEEECC
EFAVLKALVQHPREPLTRDKLMNLARGREWGAMERSIDVQVSRLRRLIEDNPARARYIQT
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VWGIGYVFVPDGAE
HHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]