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The map label for this gene is czcB [H]

Identifier: 50086353

GI number: 50086353

Start: 3286833

End: 3288086

Strand: Reverse

Name: czcB [H]

Synonym: ACIAD3376

Alternate gene names: 50086353

Gene position: 3288086-3286833 (Counterclockwise)

Preceding gene: 50086354

Following gene: 50086352

Centisome position: 91.37

GC content: 50.24

Gene sequence:

>1254_bases
ATGTTAACAAAAAAATCGCAGTGGTTTTGGGTGGTGCTGGTATTGATCATCAGTCTGGTCGTGGCAGGCATATTGCTATT
CTCCGGCAAAAAATCGAGTGCTATGAATGGCGGTGAAGCTGAGCATGCACATGCAGAGGCGCAAGAGGCTAAGACTAAAG
AATCCGGTCATGAAGCACATCAAGAAAAAGCCACAGAGGCGCATCAAGAAGAGCAGCCAGAACTGATCTTTACAGCCCAG
CAGCTTCAGCAATTTGGCATTGTGACTGATCGTGTGCGTTTGGGCGAAATTCAGCAACAGACCCGGCATCCGGCGAAACT
GGTGGTCAATACCGATGCGCAGGCGCATGTGGGAGCATCTTTTATGGCGCAAGTCGAGCAAGTGAATGTCAGTCTTGGAC
AGTCGGTTAAAAAAGGGCAAGTCTTGGCGACGCTATTTGTTCCCGAGTTGATTGATCAACAGGCCAATTTAAGTCTGGCA
CGTGAAGCACTCAATCTTGCAGCGCAAGACTATCAACGTGAGAAGCAACTGATGAATCAAGGCGTGTCTGCACGTCAGGA
CTATCAGCGTGCATACAATGCCTATCGTCAGGCACAAATTCAGGTTCAGGCGGCGACACAGCGGCTTTTGGCCTACGGGG
CCAGCGCAGGAAGTCAGGGCCGATATGCTGTGCGTGCGCCGCTGAGTGGCACCATCAGCAGCAAAGATATTGTGGTGGGC
GAGCAAGTCGCGACAGGTAAACCTTTGTTTGTCATTGATCAGCTCGATCAGTTATGGCTGGAGTTTATTTTGCCCAATAG
CAGCACAGTCGCCATGCAACCAGGTCAAAAAATAAAATTTGTTTCCTTGCAAACCCAACATGAGTTTGAGGCACAAATTC
AGAGCTTAACCGCACAGGCCGATCAAGACACTGGTCGTCTGCAAGTACGTGGCAAGGTGCTGACTGCGGCCAAAGAACTG
CGTCCGAATTTGATGGTTAATGTACTGCTCGAAACACCTAATCCTGTGCCTGTTCTGCGTGTAGACAAGCGTGCGATTCA
GCAACGAGAAGGCCAGTCGGTGGTGTTTGTGGTCTCTCAAGACAAAAAAGGGCTGCGCTTTGAGCCAAAGCCTGTACAAA
CCGGTCGCTACTCGAGCGATGGTGCATGGGTTGAAATTGTCTCTGGGCTGACCCAACAGCAGCATTATGTGCGTGAGGGA
AGCTTCGTTTTGAAATCTGAACTGGAAAAAGGCGAGGCTGAGCATGGACACTAA

Upstream 100 bases:

>100_bases
TTTCACCCGATACGATTATGTCGGCCGATGCCTTGGAACAACTCCAGTACACCCTCTGGCAAGACACGCAAAGCCTCAAT
ACTGGTAATGGAGCAAACTA

Downstream 100 bases:

>100_bases
GCACACAAATAGCTTGCCGCCTGCACAAGGGCTTTTCGATCGTTTGATCCAGTTCGCCATCCAGAATGCCATCTGGGTGT
TGCTGTTTATGGTCGCATGG

Product: RND divalent metal cation efflux membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MLTKKSQWFWVVLVLIISLVVAGILLFSGKKSSAMNGGEAEHAHAEAQEAKTKESGHEAHQEKATEAHQEEQPELIFTAQ
QLQQFGIVTDRVRLGEIQQQTRHPAKLVVNTDAQAHVGASFMAQVEQVNVSLGQSVKKGQVLATLFVPELIDQQANLSLA
REALNLAAQDYQREKQLMNQGVSARQDYQRAYNAYRQAQIQVQAATQRLLAYGASAGSQGRYAVRAPLSGTISSKDIVVG
EQVATGKPLFVIDQLDQLWLEFILPNSSTVAMQPGQKIKFVSLQTQHEFEAQIQSLTAQADQDTGRLQVRGKVLTAAKEL
RPNLMVNVLLETPNPVPVLRVDKRAIQQREGQSVVFVVSQDKKGLRFEPKPVQTGRYSSDGAWVEIVSGLTQQQHYVREG
SFVLKSELEKGEAEHGH

Sequences:

>Translated_417_residues
MLTKKSQWFWVVLVLIISLVVAGILLFSGKKSSAMNGGEAEHAHAEAQEAKTKESGHEAHQEKATEAHQEEQPELIFTAQ
QLQQFGIVTDRVRLGEIQQQTRHPAKLVVNTDAQAHVGASFMAQVEQVNVSLGQSVKKGQVLATLFVPELIDQQANLSLA
REALNLAAQDYQREKQLMNQGVSARQDYQRAYNAYRQAQIQVQAATQRLLAYGASAGSQGRYAVRAPLSGTISSKDIVVG
EQVATGKPLFVIDQLDQLWLEFILPNSSTVAMQPGQKIKFVSLQTQHEFEAQIQSLTAQADQDTGRLQVRGKVLTAAKEL
RPNLMVNVLLETPNPVPVLRVDKRAIQQREGQSVVFVVSQDKKGLRFEPKPVQTGRYSSDGAWVEIVSGLTQQQHYVREG
SFVLKSELEKGEAEHGH
>Mature_417_residues
MLTKKSQWFWVVLVLIISLVVAGILLFSGKKSSAMNGGEAEHAHAEAQEAKTKESGHEAHQEKATEAHQEEQPELIFTAQ
QLQQFGIVTDRVRLGEIQQQTRHPAKLVVNTDAQAHVGASFMAQVEQVNVSLGQSVKKGQVLATLFVPELIDQQANLSLA
REALNLAAQDYQREKQLMNQGVSARQDYQRAYNAYRQAQIQVQAATQRLLAYGASAGSQGRYAVRAPLSGTISSKDIVVG
EQVATGKPLFVIDQLDQLWLEFILPNSSTVAMQPGQKIKFVSLQTQHEFEAQIQSLTAQADQDTGRLQVRGKVLTAAKEL
RPNLMVNVLLETPNPVPVLRVDKRAIQQREGQSVVFVVSQDKKGLRFEPKPVQTGRYSSDGAWVEIVSGLTQQQHYVREG
SFVLKSELEKGEAEHGH

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=348, Percent_Identity=24.1379310344828, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 46099; Mature: 46099

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTKKSQWFWVVLVLIISLVVAGILLFSGKKSSAMNGGEAEHAHAEAQEAKTKESGHEAH
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QEKATEAHQEEQPELIFTAQQLQQFGIVTDRVRLGEIQQQTRHPAKLVVNTDAQAHVGAS
HHHHHHHHHHCCCCEEEEHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHH
FMAQVEQVNVSLGQSVKKGQVLATLFVPELIDQQANLSLAREALNLAAQDYQREKQLMNQ
HHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GVSARQDYQRAYNAYRQAQIQVQAATQRLLAYGASAGSQGRYAVRAPLSGTISSKDIVVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEEC
EQVATGKPLFVIDQLDQLWLEFILPNSSTVAMQPGQKIKFVSLQTQHEFEAQIQSLTAQA
CCCCCCCCEEEEHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCHHHHHHHHHHHHHC
DQDTGRLQVRGKVLTAAKELRPNLMVNVLLETPNPVPVLRVDKRAIQQREGQSVVFVVSQ
CCCCCEEEEEHHHHHHHHHHCCCEEEEEEEECCCCCCEEEECHHHHHHCCCCEEEEEEEC
DKKGLRFEPKPVQTGRYSSDGAWVEIVSGLTQQQHYVREGSFVLKSELEKGEAEHGH
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLTKKSQWFWVVLVLIISLVVAGILLFSGKKSSAMNGGEAEHAHAEAQEAKTKESGHEAH
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QEKATEAHQEEQPELIFTAQQLQQFGIVTDRVRLGEIQQQTRHPAKLVVNTDAQAHVGAS
HHHHHHHHHHCCCCEEEEHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHH
FMAQVEQVNVSLGQSVKKGQVLATLFVPELIDQQANLSLAREALNLAAQDYQREKQLMNQ
HHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GVSARQDYQRAYNAYRQAQIQVQAATQRLLAYGASAGSQGRYAVRAPLSGTISSKDIVVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEEC
EQVATGKPLFVIDQLDQLWLEFILPNSSTVAMQPGQKIKFVSLQTQHEFEAQIQSLTAQA
CCCCCCCCEEEEHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCHHHHHHHHHHHHHC
DQDTGRLQVRGKVLTAAKELRPNLMVNVLLETPNPVPVLRVDKRAIQQREGQSVVFVVSQ
CCCCCEEEEEHHHHHHHHHHCCCEEEEEEEECCCCCCEEEECHHHHHHCCCCEEEEEEEC
DKKGLRFEPKPVQTGRYSSDGAWVEIVSGLTQQQHYVREGSFVLKSELEKGEAEHGH
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]