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The map label for this gene is grx [H]

Identifier: 50086125

GI number: 50086125

Start: 3050476

End: 3050733

Strand: Direct

Name: grx [H]

Synonym: ACIAD3121

Alternate gene names: 50086125

Gene position: 3050476-3050733 (Clockwise)

Preceding gene: 50086124

Following gene: 50086126

Centisome position: 84.77

GC content: 40.7

Gene sequence:

>258_bases
ATGGCGGCAAATATCACCATTTATTCGACCACGGTGTGTCCGTATTGCATTCGTGCAAAACAACTACTTGAGCGCAAAGG
CGTTAAATATAAAGAAATCAATCTGTCCAATGAAGCACCAGAAGTACGTGTTGAATTAATGCAACGCACCCATCACCGTA
CAGTGCCTCAAATTTTTATCAATGACCAGTTTATTGGCGGTTTTGATCAGCTTTATGCTTTAGAGCGTGATGGTAAACTC
GACGAATTATTGGCTTAA

Upstream 100 bases:

>100_bases
CCATGCCGACAGCTACCGCCTTGATGGTGGAATCAGCAATTGGAAAGCACAAGGCTTACCTTTAGTTAAAGCAAAAACCA
AAGCTTAAGGAGTTAACCTC

Downstream 100 bases:

>100_bases
TCTCGCTTTGTACAGTAAAGGAAAAAAGAATGAGTGAAGAACAACAAACTCAACCACAACTTGCTTTAGAACGTCTTTAT
ACCAAAGATATTTCATTTGA

Product: glutaredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MAANITIYSTTVCPYCIRAKQLLERKGVKYKEINLSNEAPEVRVELMQRTHHRTVPQIFINDQFIGGFDQLYALERDGKL
DELLA

Sequences:

>Translated_85_residues
MAANITIYSTTVCPYCIRAKQLLERKGVKYKEINLSNEAPEVRVELMQRTHHRTVPQIFINDQFIGGFDQLYALERDGKL
DELLA
>Mature_84_residues
AANITIYSTTVCPYCIRAKQLLERKGVKYKEINLSNEAPEVRVELMQRTHHRTVPQIFINDQFIGGFDQLYALERDGKLD
ELLA

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=82, Percent_Identity=51.219512195122, Blast_Score=86, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9826; Mature: 9695

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAANITIYSTTVCPYCIRAKQLLERKGVKYKEINLSNEAPEVRVELMQRTHHRTVPQIFI
CCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEE
NDQFIGGFDQLYALERDGKLDELLA
CCCCCCCHHHHEEECCCCCHHHHCC
>Mature Secondary Structure 
AANITIYSTTVCPYCIRAKQLLERKGVKYKEINLSNEAPEVRVELMQRTHHRTVPQIFI
CCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEE
NDQFIGGFDQLYALERDGKLDELLA
CCCCCCCHHHHEEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]