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The map label for this gene is pkn1 [H]

Identifier: 50086116

GI number: 50086116

Start: 3038267

End: 3039250

Strand: Direct

Name: pkn1 [H]

Synonym: ACIAD3112

Alternate gene names: 50086116

Gene position: 3038267-3039250 (Clockwise)

Preceding gene: 50086115

Following gene: 50086117

Centisome position: 84.43

GC content: 39.33

Gene sequence:

>984_bases
ATGACTTATAAAAAGATGATGAAACAAAATCTTGTAATTTTTTTATTTTCAACTCTTGCTTTAAATGCCTGTGCAAAATC
GAGAGAAACATCCACCAAAGCAGCTCAGCCTTCAGCCGAATTACAACAAAAAATTCAAAAGCTCGTTGAGAAAACCCAAA
AAAATATGATTTTTGTTGAGGGTGGAAGCTTTATGATGGGTGATTTTGGTCATGTCACACGTAAAGATAAATTACCTATC
ACTGGCCTTTATGTAGCCATGCCTTTACATAAAGTCACCCTCGATAGTTTTAGTTTAAATGCGTATAAAACCACCTTTGA
TGAGTTTGATATTTATACTGAAGCGACTGGGCAGAAAAAAATTGCAATGCAAGAAATTTCCAAAAAGTTACGCGTACCAA
ATGCACCCGCAGGTGTGAGCTGGCAACAAGCACACGATTACTGTCAATGGCTAGGCCAACAAGTTGGAATACCTATGACC
CTACCAACCGAAGCGCAATGGGAATATGCTGCCAGAAACCGTGGGCAATATGTTATCTATCCAACGGATAATGGTGAATA
TGAGCCGGGACGAAATGTTTGGAGTGATGAACAAAGACGTGAATTTACTAAATCTATGCCCGATATTCATGGAGTAAAAG
TTCCGACACTTGGTCGGTTTCCTCCGACACCTTTAGGCTTTTATGACTTAGCAACTGATAGCTATGAATGGATGTCGGAT
TGGTTTGATCCTCAATATTATAAGCATTCACCAGAGAAAAACCCTCAAGGCCCAGCGACAGGGACACTCAAATCGGTTCG
AAGCACTTATCAGGAGGCTGGTGTTTTAGATCTAAAAATTGGCGGTAGTGTAACAACAATTTATAGATATGGTGTGGAAC
CTAATCCTAAATTTGATAAGGATGACAATGCTTTCAATACTATTAACCCAAATAGTGCAACCGCTGTAAGATGCGCCTCT
AACTCGCATAAACCATTTATCTAA

Upstream 100 bases:

>100_bases
AAACTATTTATGGCAATACTTCAAACTCTCATTAGCTAACACAAAGCTTCTTTTCAAGCAACTATACCTCACTTAAAATT
TATACAACATTCGTAACGTT

Downstream 100 bases:

>100_bases
AATAAAAGGAGTTAAATGACATTTTATAGGCTGTTAAATTTATTCATTGATAAATACAGCTAACTCTAATCATTTAACAT
TAAGTTTCTTTTCAAGAATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTYKKMMKQNLVIFLFSTLALNACAKSRETSTKAAQPSAELQQKIQKLVEKTQKNMIFVEGGSFMMGDFGHVTRKDKLPI
TGLYVAMPLHKVTLDSFSLNAYKTTFDEFDIYTEATGQKKIAMQEISKKLRVPNAPAGVSWQQAHDYCQWLGQQVGIPMT
LPTEAQWEYAARNRGQYVIYPTDNGEYEPGRNVWSDEQRREFTKSMPDIHGVKVPTLGRFPPTPLGFYDLATDSYEWMSD
WFDPQYYKHSPEKNPQGPATGTLKSVRSTYQEAGVLDLKIGGSVTTIYRYGVEPNPKFDKDDNAFNTINPNSATAVRCAS
NSHKPFI

Sequences:

>Translated_327_residues
MTYKKMMKQNLVIFLFSTLALNACAKSRETSTKAAQPSAELQQKIQKLVEKTQKNMIFVEGGSFMMGDFGHVTRKDKLPI
TGLYVAMPLHKVTLDSFSLNAYKTTFDEFDIYTEATGQKKIAMQEISKKLRVPNAPAGVSWQQAHDYCQWLGQQVGIPMT
LPTEAQWEYAARNRGQYVIYPTDNGEYEPGRNVWSDEQRREFTKSMPDIHGVKVPTLGRFPPTPLGFYDLATDSYEWMSD
WFDPQYYKHSPEKNPQGPATGTLKSVRSTYQEAGVLDLKIGGSVTTIYRYGVEPNPKFDKDDNAFNTINPNSATAVRCAS
NSHKPFI
>Mature_326_residues
TYKKMMKQNLVIFLFSTLALNACAKSRETSTKAAQPSAELQQKIQKLVEKTQKNMIFVEGGSFMMGDFGHVTRKDKLPIT
GLYVAMPLHKVTLDSFSLNAYKTTFDEFDIYTEATGQKKIAMQEISKKLRVPNAPAGVSWQQAHDYCQWLGQQVGIPMTL
PTEAQWEYAARNRGQYVIYPTDNGEYEPGRNVWSDEQRREFTKSMPDIHGVKVPTLGRFPPTPLGFYDLATDSYEWMSDW
FDPQYYKHSPEKNPQGPATGTLKSVRSTYQEAGVLDLKIGGSVTTIYRYGVEPNPKFDKDDNAFNTINPNSATAVRCASN
SHKPFI

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=297, Percent_Identity=26.5993265993266, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI38202250, Length=322, Percent_Identity=25.1552795031056, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 37005; Mature: 36874

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYKKMMKQNLVIFLFSTLALNACAKSRETSTKAAQPSAELQQKIQKLVEKTQKNMIFVE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCCEEEEE
GGSFMMGDFGHVTRKDKLPITGLYVAMPLHKVTLDSFSLNAYKTTFDEFDIYTEATGQKK
CCCEEECCCCCCCCCCCCCEEEEEEECCHHHEECCCEECCHHHCCHHHHHEEECCCCCHH
IAMQEISKKLRVPNAPAGVSWQQAHDYCQWLGQQVGIPMTLPTEAQWEYAARNRGQYVIY
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHCCCCCEEEE
PTDNGEYEPGRNVWSDEQRREFTKSMPDIHGVKVPTLGRFPPTPLGFYDLATDSYEWMSD
ECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHH
WFDPQYYKHSPEKNPQGPATGTLKSVRSTYQEAGVLDLKIGGSVTTIYRYGVEPNPKFDK
CCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCEEEEEEECCCCCCCCCC
DDNAFNTINPNSATAVRCASNSHKPFI
CCCCCCCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
TYKKMMKQNLVIFLFSTLALNACAKSRETSTKAAQPSAELQQKIQKLVEKTQKNMIFVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCCEEEEE
GGSFMMGDFGHVTRKDKLPITGLYVAMPLHKVTLDSFSLNAYKTTFDEFDIYTEATGQKK
CCCEEECCCCCCCCCCCCCEEEEEEECCHHHEECCCEECCHHHCCHHHHHEEECCCCCHH
IAMQEISKKLRVPNAPAGVSWQQAHDYCQWLGQQVGIPMTLPTEAQWEYAARNRGQYVIY
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHCCCCCEEEE
PTDNGEYEPGRNVWSDEQRREFTKSMPDIHGVKVPTLGRFPPTPLGFYDLATDSYEWMSD
ECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHH
WFDPQYYKHSPEKNPQGPATGTLKSVRSTYQEAGVLDLKIGGSVTTIYRYGVEPNPKFDK
CCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCEEEEEEECCCCCCCCCC
DDNAFNTINPNSATAVRCASNSHKPFI
CCCCCCCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]