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The map label for this gene is kdpE [H]

Identifier: 50085995

GI number: 50085995

Start: 2900378

End: 2901091

Strand: Reverse

Name: kdpE [H]

Synonym: ACIAD2973

Alternate gene names: 50085995

Gene position: 2901091-2900378 (Counterclockwise)

Preceding gene: 50085996

Following gene: 50085994

Centisome position: 80.62

GC content: 46.78

Gene sequence:

>714_bases
ATGTCGCACAGCTTTAATACACAGGCCTCGATTTTGATTATCGACGATGAGCCACAGATTCGTAAATTTCTCGATATTGC
CTTACGCGCGCAGGGTTATGCGGTGCATGTGGCTGAAACTGGCATGAAAGGGCTGGAAATTTTGGCCTCTCAAGGGGCAG
ATCTGCTGATTTTAGATTTGGGCCTACCCGACATGGATGGTGCAGAGGTATTAAAAGAGATGCGGCAATGGTCGCAAATT
CCGGTCATCGTACTCTCTGCACGTCCAGACGAGCAGCAAAAAATTAAGTTGCTCGATGCGGGTGCCAATGATTACGTGAC
CAAACCATTTAGTATTCAGGAGTTATGTGCCCGGATTCGGGTGATGTTTCGTCAGCAACCGAGTCAAAGTGAGCATAATC
TGGTTTTTAATGATGGACAGCTTTTTGTCGATGTCGCGGAGCATAGCGTGAAACTGGCTGGAGACGACGTGGTACTCACC
AAAAAAGAGTTTCAGCTACTGGCCTTACTCATTCGGCATCAGGGTAAAATTGTGACCCAAAAGCAGATCTTGTCGGAGCT
TTGGGGCATTACGCATGAAGAGGACACGCATTATTTGCGTATTTTGGTCAAAAAACTCAGAACCAAGCTAGGCGACTCAG
CGCTACAACCACATTATATTTTTACTGTTGCGGGCATTGGTTTGCGCTTTCAGAGTGATGTTGGCAGCTCTTAA

Upstream 100 bases:

>100_bases
CGGGGCACATATGGGGAGCATTGAAGCAATGGCTGGGCCGTATGGTCAAGGCACCCAAATTCGAATACGATTACCTCAAC
ACCAAGAATAACGATGATTT

Downstream 100 bases:

>100_bases
CGAGATGAGACCAAGGCGTCTGACATCACAAATTCTTCACCTTCATTTCGCTAAAGTGATGCACTAAAATCGCTGTGTTG
TCTCAGCAATCCTTAGTCAA

Product: regulator of kdp operon (transcriptional effector)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSHSFNTQASILIIDDEPQIRKFLDIALRAQGYAVHVAETGMKGLEILASQGADLLILDLGLPDMDGAEVLKEMRQWSQI
PVIVLSARPDEQQKIKLLDAGANDYVTKPFSIQELCARIRVMFRQQPSQSEHNLVFNDGQLFVDVAEHSVKLAGDDVVLT
KKEFQLLALLIRHQGKIVTQKQILSELWGITHEEDTHYLRILVKKLRTKLGDSALQPHYIFTVAGIGLRFQSDVGSS

Sequences:

>Translated_237_residues
MSHSFNTQASILIIDDEPQIRKFLDIALRAQGYAVHVAETGMKGLEILASQGADLLILDLGLPDMDGAEVLKEMRQWSQI
PVIVLSARPDEQQKIKLLDAGANDYVTKPFSIQELCARIRVMFRQQPSQSEHNLVFNDGQLFVDVAEHSVKLAGDDVVLT
KKEFQLLALLIRHQGKIVTQKQILSELWGITHEEDTHYLRILVKKLRTKLGDSALQPHYIFTVAGIGLRFQSDVGSS
>Mature_236_residues
SHSFNTQASILIIDDEPQIRKFLDIALRAQGYAVHVAETGMKGLEILASQGADLLILDLGLPDMDGAEVLKEMRQWSQIP
VIVLSARPDEQQKIKLLDAGANDYVTKPFSIQELCARIRVMFRQQPSQSEHNLVFNDGQLFVDVAEHSVKLAGDDVVLTK
KEFQLLALLIRHQGKIVTQKQILSELWGITHEEDTHYLRILVKKLRTKLGDSALQPHYIFTVAGIGLRFQSDVGSS

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=45.7013574660633, Blast_Score=196, Evalue=9e-52,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=36.8181818181818, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=33.4841628959276, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=33.9449541284404, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=35.3211009174312, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=31.390134529148, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=30.6306306306306, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=30.9417040358744, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=29.6943231441048, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787229, Length=208, Percent_Identity=29.3269230769231, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=29.004329004329, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=27.8969957081545, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI2367329, Length=223, Percent_Identity=30.9417040358744, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=39.622641509434, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=26.2931034482759, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1790299, Length=129, Percent_Identity=34.8837209302326, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=146, Percent_Identity=32.8767123287671, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=31.9327731092437, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790437, Length=110, Percent_Identity=33.6363636363636, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI145693157, Length=110, Percent_Identity=30, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789149, Length=109, Percent_Identity=31.1926605504587, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1788905, Length=110, Percent_Identity=34.5454545454545, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26566; Mature: 26435

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSFNTQASILIIDDEPQIRKFLDIALRAQGYAVHVAETGMKGLEILASQGADLLILDL
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCEEEEEC
GLPDMDGAEVLKEMRQWSQIPVIVLSARPDEQQKIKLLDAGANDYVTKPFSIQELCARIR
CCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHEEEEEECCCCCCCCCCCCHHHHHHHHH
VMFRQQPSQSEHNLVFNDGQLFVDVAEHSVKLAGDDVVLTKKEFQLLALLIRHQGKIVTQ
HHHHCCCCCCCCCEEEECCEEEEEEECCEEEECCCCEEEEHHHHHHHHHHHHHCCCEEHH
KQILSELWGITHEEDTHYLRILVKKLRTKLGDSALQPHYIFTVAGIGLRFQSDVGSS
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEECCCCCCC
>Mature Secondary Structure 
SHSFNTQASILIIDDEPQIRKFLDIALRAQGYAVHVAETGMKGLEILASQGADLLILDL
CCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCEEEEEC
GLPDMDGAEVLKEMRQWSQIPVIVLSARPDEQQKIKLLDAGANDYVTKPFSIQELCARIR
CCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHEEEEEECCCCCCCCCCCCHHHHHHHHH
VMFRQQPSQSEHNLVFNDGQLFVDVAEHSVKLAGDDVVLTKKEFQLLALLIRHQGKIVTQ
HHHHCCCCCCCCCEEEECCEEEEEEECCEEEECCCCEEEEHHHHHHHHHHHHHCCCEEHH
KQILSELWGITHEEDTHYLRILVKKLRTKLGDSALQPHYIFTVAGIGLRFQSDVGSS
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]