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The map label for this gene is qmcA [H]

Identifier: 50085990

GI number: 50085990

Start: 2895832

End: 2896689

Strand: Direct

Name: qmcA [H]

Synonym: ACIAD2967

Alternate gene names: 50085990

Gene position: 2895832-2896689 (Clockwise)

Preceding gene: 50085989

Following gene: 50085992

Centisome position: 80.47

GC content: 45.92

Gene sequence:

>858_bases
ATGTCAGTGGGTTTAATTATTGGCTTAGCCTTTCTTGTATTTGTTGGCGTCACTATTTTTAAAGGTGTACGCATTGTTCC
TCAGGGTTATAAATGGATTGTACAGCGTTTAGGTAAATACCATTCCACCCTGAATCCAGGTTTAAATTTTGTGATTCCTT
ATATTGATGAAATTGCATATAAAGTCACCACAAAGGACATTGTGCTGGATATTCCCTCGCAAGAAGTGATTACCCGTGAC
AATGCCGTGCTGGTGATGAATGCTGTTGCATATATTAACTTAACCACGCCTGAGAAAGCCGTGTATGGGATTGAAAACTA
TACATGGGCCATTCAAAATCTGGTGCAGACATCGCTTCGCTCGATTGTTGGTGAAATGGATCTGGATGATGCCTTGTCAT
CTCGTGATCACATCAAAGCCAAATTAAAAGCCGCGATTTCGGATGACATTTCAGATTGGGGCATTACCTTAAAAACAGTT
GAAATTCAGGATATCCAACCATCGACCACCATGCAGGCCGCGATGGAAGCACAAGCTGCAGCCGAGCGTCAGCGCCGTGC
GACCGTGACCCGTGCCGATGGTGAAAAACAGGCGGCGATTTTGGAAGCCGATGGCCGCCTTGAAGCATCAAGACGTGATG
CCGAAGCACAGGTCGTCCTTGCAGAAGCCTCTCAAAAGGCGATTGAAATGGTGACTTCTGCAGTAGGTGAACAGGAAATT
CCGGTTGCGTATTTGCTGGGTGAGCAATACATCAAAGCCATGCAAGAAATGGCAAAATCCAACAATGCCAAAACCGTGGT
GATTCCTGCCGATGTGCTGAGTACCATCCGAGGTGTGATGGGCCGTTCACAAAACTAA

Upstream 100 bases:

>100_bases
TCCTGTGGAAGTTGGTGATCGTGTCTGTGTCGTCGATATCATGGGCAATGATCTGGTTGTCCAGCCCCATATCCCAATAA
ACAATAAATGAGGACATTTT

Downstream 100 bases:

>100_bases
AGCCAGACGCATTCAATAAAAAAGCGGTTTCATCTTTTATGAAACCGCTTTTTTAATACAACAATTTTGGAAGAATTAAC
TTTTTCGCGATAATAAAAAC

Product: membrane protease subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSVGLIIGLAFLVFVGVTIFKGVRIVPQGYKWIVQRLGKYHSTLNPGLNFVIPYIDEIAYKVTTKDIVLDIPSQEVITRD
NAVLVMNAVAYINLTTPEKAVYGIENYTWAIQNLVQTSLRSIVGEMDLDDALSSRDHIKAKLKAAISDDISDWGITLKTV
EIQDIQPSTTMQAAMEAQAAAERQRRATVTRADGEKQAAILEADGRLEASRRDAEAQVVLAEASQKAIEMVTSAVGEQEI
PVAYLLGEQYIKAMQEMAKSNNAKTVVIPADVLSTIRGVMGRSQN

Sequences:

>Translated_285_residues
MSVGLIIGLAFLVFVGVTIFKGVRIVPQGYKWIVQRLGKYHSTLNPGLNFVIPYIDEIAYKVTTKDIVLDIPSQEVITRD
NAVLVMNAVAYINLTTPEKAVYGIENYTWAIQNLVQTSLRSIVGEMDLDDALSSRDHIKAKLKAAISDDISDWGITLKTV
EIQDIQPSTTMQAAMEAQAAAERQRRATVTRADGEKQAAILEADGRLEASRRDAEAQVVLAEASQKAIEMVTSAVGEQEI
PVAYLLGEQYIKAMQEMAKSNNAKTVVIPADVLSTIRGVMGRSQN
>Mature_284_residues
SVGLIIGLAFLVFVGVTIFKGVRIVPQGYKWIVQRLGKYHSTLNPGLNFVIPYIDEIAYKVTTKDIVLDIPSQEVITRDN
AVLVMNAVAYINLTTPEKAVYGIENYTWAIQNLVQTSLRSIVGEMDLDDALSSRDHIKAKLKAAISDDISDWGITLKTVE
IQDIQPSTTMQAAMEAQAAAERQRRATVTRADGEKQAAILEADGRLEASRRDAEAQVVLAEASQKAIEMVTSAVGEQEIP
VAYLLGEQYIKAMQEMAKSNNAKTVVIPADVLSTIRGVMGRSQN

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=288, Percent_Identity=32.2916666666667, Blast_Score=160, Evalue=9e-40,
Organism=Homo sapiens, GI38016911, Length=280, Percent_Identity=29.6428571428571, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI221316744, Length=281, Percent_Identity=28.1138790035587, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI21686995, Length=281, Percent_Identity=28.1138790035587, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI7657615, Length=183, Percent_Identity=26.775956284153, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1786697, Length=290, Percent_Identity=37.9310344827586, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1790616, Length=220, Percent_Identity=24.5454545454545, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32564147, Length=270, Percent_Identity=35.1851851851852, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17569493, Length=188, Percent_Identity=34.5744680851064, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI193209764, Length=188, Percent_Identity=34.5744680851064, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17569497, Length=202, Percent_Identity=31.6831683168317, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17569499, Length=205, Percent_Identity=29.7560975609756, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17570459, Length=185, Percent_Identity=29.1891891891892, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32566490, Length=200, Percent_Identity=29.5, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71989955, Length=184, Percent_Identity=31.5217391304348, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71989948, Length=184, Percent_Identity=31.5217391304348, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71987621, Length=269, Percent_Identity=26.0223048327138, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71987612, Length=269, Percent_Identity=26.3940520446097, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25153583, Length=269, Percent_Identity=26.3940520446097, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17542664, Length=167, Percent_Identity=27.5449101796407, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193210507, Length=208, Percent_Identity=25.4807692307692, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17570161, Length=208, Percent_Identity=25.4807692307692, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71989963, Length=135, Percent_Identity=31.1111111111111, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45550506, Length=267, Percent_Identity=33.7078651685393, Blast_Score=158, Evalue=4e-39,
Organism=Drosophila melanogaster, GI18860517, Length=198, Percent_Identity=33.3333333333333, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281361631, Length=249, Percent_Identity=26.9076305220884, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281361633, Length=249, Percent_Identity=26.9076305220884, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI45556022, Length=210, Percent_Identity=31.4285714285714, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356845, Length=188, Percent_Identity=26.063829787234, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI28573263, Length=183, Percent_Identity=27.3224043715847, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI62484448, Length=202, Percent_Identity=32.6732673267327, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI62484274, Length=202, Percent_Identity=32.6732673267327, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24657857, Length=202, Percent_Identity=32.6732673267327, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281365664, Length=202, Percent_Identity=32.6732673267327, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281361635, Length=181, Percent_Identity=25.9668508287293, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 31210; Mature: 31079

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVGLIIGLAFLVFVGVTIFKGVRIVPQGYKWIVQRLGKYHSTLNPGLNFVIPYIDEIAY
CCHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHH
KVTTKDIVLDIPSQEVITRDNAVLVMNAVAYINLTTPEKAVYGIENYTWAIQNLVQTSLR
HEECCEEEEECCCHHHEECCCEEEEEEEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHH
SIVGEMDLDDALSSRDHIKAKLKAAISDDISDWGITLKTVEIQDIQPSTTMQAAMEAQAA
HHHCCCCHHHHHCCHHHHHHHHHHHHHCCCHHCCEEEEEEEEECCCCHHHHHHHHHHHHH
AERQRRATVTRADGEKQAAILEADGRLEASRRDAEAQVVLAEASQKAIEMVTSAVGEQEI
HHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCC
PVAYLLGEQYIKAMQEMAKSNNAKTVVIPADVLSTIRGVMGRSQN
CHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SVGLIIGLAFLVFVGVTIFKGVRIVPQGYKWIVQRLGKYHSTLNPGLNFVIPYIDEIAY
CHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHH
KVTTKDIVLDIPSQEVITRDNAVLVMNAVAYINLTTPEKAVYGIENYTWAIQNLVQTSLR
HEECCEEEEECCCHHHEECCCEEEEEEEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHH
SIVGEMDLDDALSSRDHIKAKLKAAISDDISDWGITLKTVEIQDIQPSTTMQAAMEAQAA
HHHCCCCHHHHHCCHHHHHHHHHHHHHCCCHHCCEEEEEEEEECCCCHHHHHHHHHHHHH
AERQRRATVTRADGEKQAAILEADGRLEASRRDAEAQVVLAEASQKAIEMVTSAVGEQEI
HHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCC
PVAYLLGEQYIKAMQEMAKSNNAKTVVIPADVLSTIRGVMGRSQN
CHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]