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The map label for this gene is qseB [H]

Identifier: 50085985

GI number: 50085985

Start: 2891169

End: 2891849

Strand: Reverse

Name: qseB [H]

Synonym: ACIAD2961

Alternate gene names: 50085985

Gene position: 2891849-2891169 (Counterclockwise)

Preceding gene: 50085986

Following gene: 50085984

Centisome position: 80.36

GC content: 37.15

Gene sequence:

>681_bases
ATGACCAAAATATTGATTATTGAAGATGATTTCATGATCGCTGAATCTACCATTACCTTATTGAAATATCATCAATTTGA
GGTGGAATGGGTCAATAATGGATTTGATGGCTTGGCACACCTTGCAAAACAAAGTTTTGATTTGGTATTACTCGATCTTG
GCCTGCCTATGATGGATGGTATGCAGGTACTTAAGCAGATTCGTCAGAAAACTGGCGTACCAGTTTTAATTATTTCAGCA
CGTGATCAACTTGAAAATCGTGTTGAAGGTCTAAATCAGGGCGCAGATGATTATTTAATCAAGCCTTATGAATTTGATGA
ATTACTTGCACGTATTAATGCATTGTTACGCCGTACCAACAGCAAAGATGCATCTTCATTGCAACAAGATCAGGTCTTGA
GCAATGGTGAAGTGATTTTGAATGTTGAAAAACATATTGCAACTTTTCAAGGTAAGGAAATTGAACTTTCTAATCGTGAA
TGGGCGATTCTGATTCCATTGATGACGCACCCCAACAAGATTTTTTCTAAAGCCAATCTTGAAGATAAACTGTACGATTT
TGATAGTGAAGTGACCAGTAATACCATTGAAGTGTATATTCATCACTTGCGCTCGAAGCTAGGCAAAAATTTTATTCGTA
CTATTCGTGGATTAGGCTACCGACTGGGTCAGACATCATAA

Upstream 100 bases:

>100_bases
CTTCTCTAAAGTAGTCAGTGGATATGAAAAAAAACAATGTGTTGTTTATCCACTTGATATATTAGATCTATGCTATTCCA
CAGATGTGCGAGCTTAACTC

Downstream 100 bases:

>100_bases
GGAACTAGGGGATGACCCAGCATTATTCACTACGACGTCGGTTAATCTGGGTCACCTCCATATTTAGTGTTCTACTTGGA
TGTGTATTGGTCTTTACTGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTKILIIEDDFMIAESTITLLKYHQFEVEWVNNGFDGLAHLAKQSFDLVLLDLGLPMMDGMQVLKQIRQKTGVPVLIISA
RDQLENRVEGLNQGADDYLIKPYEFDELLARINALLRRTNSKDASSLQQDQVLSNGEVILNVEKHIATFQGKEIELSNRE
WAILIPLMTHPNKIFSKANLEDKLYDFDSEVTSNTIEVYIHHLRSKLGKNFIRTIRGLGYRLGQTS

Sequences:

>Translated_226_residues
MTKILIIEDDFMIAESTITLLKYHQFEVEWVNNGFDGLAHLAKQSFDLVLLDLGLPMMDGMQVLKQIRQKTGVPVLIISA
RDQLENRVEGLNQGADDYLIKPYEFDELLARINALLRRTNSKDASSLQQDQVLSNGEVILNVEKHIATFQGKEIELSNRE
WAILIPLMTHPNKIFSKANLEDKLYDFDSEVTSNTIEVYIHHLRSKLGKNFIRTIRGLGYRLGQTS
>Mature_225_residues
TKILIIEDDFMIAESTITLLKYHQFEVEWVNNGFDGLAHLAKQSFDLVLLDLGLPMMDGMQVLKQIRQKTGVPVLIISAR
DQLENRVEGLNQGADDYLIKPYEFDELLARINALLRRTNSKDASSLQQDQVLSNGEVILNVEKHIATFQGKEIELSNREW
AILIPLMTHPNKIFSKANLEDKLYDFDSEVTSNTIEVYIHHLRSKLGKNFIRTIRGLGYRLGQTS

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=45.7399103139013, Blast_Score=197, Evalue=4e-52,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=41.1504424778761, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=33.9285714285714, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=33.6283185840708, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=33.6283185840708, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=30.8370044052863, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=31.304347826087, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=31.5555555555556, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=30.2222222222222, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1787229, Length=222, Percent_Identity=30.1801801801802, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=30.3571428571429, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=33.6206896551724, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=27.6315789473684, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1790437, Length=126, Percent_Identity=41.2698412698413, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788550, Length=157, Percent_Identity=31.2101910828025, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=35.1851851851852, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25844; Mature: 25713

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKILIIEDDFMIAESTITLLKYHQFEVEWVNNGFDGLAHLAKQSFDLVLLDLGLPMMDG
CCEEEEEECCCEEHHHHHHHHHHHEEEEEEECCCHHHHHHHHHCCCCEEEEECCCCHHHH
MQVLKQIRQKTGVPVLIISARDQLENRVEGLNQGADDYLIKPYEFDELLARINALLRRTN
HHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHCC
SKDASSLQQDQVLSNGEVILNVEKHIATFQGKEIELSNREWAILIPLMTHPNKIFSKANL
CCCHHHHHHHHHHCCCCEEEEEHHHHHHHCCCEEEECCCCEEEEEEEECCCHHHHHHCCC
EDKLYDFDSEVTSNTIEVYIHHLRSKLGKNFIRTIRGLGYRLGQTS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCC
>Mature Secondary Structure 
TKILIIEDDFMIAESTITLLKYHQFEVEWVNNGFDGLAHLAKQSFDLVLLDLGLPMMDG
CEEEEEECCCEEHHHHHHHHHHHEEEEEEECCCHHHHHHHHHCCCCEEEEECCCCHHHH
MQVLKQIRQKTGVPVLIISARDQLENRVEGLNQGADDYLIKPYEFDELLARINALLRRTN
HHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHCC
SKDASSLQQDQVLSNGEVILNVEKHIATFQGKEIELSNREWAILIPLMTHPNKIFSKANL
CCCHHHHHHHHHHCCCCEEEEEHHHHHHHCCCEEEECCCCEEEEEEEECCCHHHHHHCCC
EDKLYDFDSEVTSNTIEVYIHHLRSKLGKNFIRTIRGLGYRLGQTS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]