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The map label for this gene is qseC [H]

Identifier: 50085984

GI number: 50085984

Start: 2889832

End: 2891157

Strand: Reverse

Name: qseC [H]

Synonym: ACIAD2960

Alternate gene names: 50085984

Gene position: 2891157-2889832 (Counterclockwise)

Preceding gene: 50085985

Following gene: 50085981

Centisome position: 80.34

GC content: 42.16

Gene sequence:

>1326_bases
ATGACCCAGCATTATTCACTACGACGTCGGTTAATCTGGGTCACCTCCATATTTAGTGTTCTACTTGGATGTGTATTGGT
CTTTACTGCCTATAAAGTGGCATTGCATGAGACCAATCAGATTCTGGATGAGCAGATGCGCTATCTGGCAGACCGTACTG
CACGCCAGCCGCTTTACAATGTCGATAGTCATTTTCAGGCCAATCATGAGTACCATGAAGAAGACCTGTTGGTTGATATC
TGGGCCTATGATGATCAAAGGCATCTACAAGATGAAAATCAGCTTCTGATTCCACCAGTTAAAAAAGCGGGATTTTATTC
GCAGGAAACCAAACAGGGCATTTTGCGCGCTTATGTACTACCTCTGGAAGATTATCAGATTCAGGTGAGCCAGTTAGAGA
AAGTGCGTAAAGTCGTAGCACTTGAACTGGCTGCAAGTATGTTCTTGCCTTACGGTATTATTTTACCGTTTGCCTTGATC
GGCTTGGCGGGAATTATCCGACGTAATCTTAAACCGTTTGATGACTTTAAGCGTGAGTTGACTCAGCGTGACTCTAGTGA
TTTATCTCCAATTCATGATGAAACTTATCCAGAAGAGCTGCTGCCAACGATTGAGGAAATGAATCGTTTATTTGAGCGAA
TATCTGAGTCGCAGCAGGAACAAAAACAGTTTGTGGCCGATGCCGCACATGAGTTAAGAACTCCTATTACCGCACTAAAT
TTACAGACCAAAATTCTGTTGAGCCAGTTTCCAGATCATGCAGCCTTACAAAACCTAGGCAAAGGTTTAGCACGTATTCA
GCATCTGGTGACGCAATTACTGGCGCTGGCCAAACAGGATGTATCGCTGAGTTCAATTGAACGCCATACCACTTTTTTAC
TCAATGATGTCACGCTCAACTGTGTAGAGCAGTTGATGAATATGGCCATGGAAAAAGAAATCGATTTAGGTTTTGAGAGA
AATGAAGATATTGAAATGGTGAGCATTGAACCGACAGTTCATTCTATTATTTTTAATTTAATTGATAATGCAATTAAATA
CACACCTGCTGCGGGCGTGATCAATATCTCTGTCTATCAAGATGAAAAAGCTTTCGCATGTGTGCAAATTGAAGACAGCG
GAGCAGGAATTGACCCACAGTATTACGATCAGGTATTGAAACGCTTTTATCGTGTTCATCATCATCTGGAAGTTGGAAGC
GGCTTAGGATTATCGATTGTTGATAAAGCCACGCAACGTTTGGGAGGTGAGCTTATTTTGGCGAAAAGCCCTGAACTTGG
CGGTTTAAGTGTATTGGTGCGCTTACCCAAGTTTTTAAAAACGTAA

Upstream 100 bases:

>100_bases
TGTATATTCATCACTTGCGCTCGAAGCTAGGCAAAAATTTTATTCGTACTATTCGTGGATTAGGCTACCGACTGGGTCAG
ACATCATAAGGAACTAGGGG

Downstream 100 bases:

>100_bases
TTTGATTGGGTCATGCAAAGCAGTTTTTGAAATCACTGGAAGTGGCTTATGCCGCTTCATGAGTCTGTTTTTAATATGCA
CACATCATGGCAATTTTAAC

Product: two-component sensor kinase transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MTQHYSLRRRLIWVTSIFSVLLGCVLVFTAYKVALHETNQILDEQMRYLADRTARQPLYNVDSHFQANHEYHEEDLLVDI
WAYDDQRHLQDENQLLIPPVKKAGFYSQETKQGILRAYVLPLEDYQIQVSQLEKVRKVVALELAASMFLPYGIILPFALI
GLAGIIRRNLKPFDDFKRELTQRDSSDLSPIHDETYPEELLPTIEEMNRLFERISESQQEQKQFVADAAHELRTPITALN
LQTKILLSQFPDHAALQNLGKGLARIQHLVTQLLALAKQDVSLSSIERHTTFLLNDVTLNCVEQLMNMAMEKEIDLGFER
NEDIEMVSIEPTVHSIIFNLIDNAIKYTPAAGVINISVYQDEKAFACVQIEDSGAGIDPQYYDQVLKRFYRVHHHLEVGS
GLGLSIVDKATQRLGGELILAKSPELGGLSVLVRLPKFLKT

Sequences:

>Translated_441_residues
MTQHYSLRRRLIWVTSIFSVLLGCVLVFTAYKVALHETNQILDEQMRYLADRTARQPLYNVDSHFQANHEYHEEDLLVDI
WAYDDQRHLQDENQLLIPPVKKAGFYSQETKQGILRAYVLPLEDYQIQVSQLEKVRKVVALELAASMFLPYGIILPFALI
GLAGIIRRNLKPFDDFKRELTQRDSSDLSPIHDETYPEELLPTIEEMNRLFERISESQQEQKQFVADAAHELRTPITALN
LQTKILLSQFPDHAALQNLGKGLARIQHLVTQLLALAKQDVSLSSIERHTTFLLNDVTLNCVEQLMNMAMEKEIDLGFER
NEDIEMVSIEPTVHSIIFNLIDNAIKYTPAAGVINISVYQDEKAFACVQIEDSGAGIDPQYYDQVLKRFYRVHHHLEVGS
GLGLSIVDKATQRLGGELILAKSPELGGLSVLVRLPKFLKT
>Mature_440_residues
TQHYSLRRRLIWVTSIFSVLLGCVLVFTAYKVALHETNQILDEQMRYLADRTARQPLYNVDSHFQANHEYHEEDLLVDIW
AYDDQRHLQDENQLLIPPVKKAGFYSQETKQGILRAYVLPLEDYQIQVSQLEKVRKVVALELAASMFLPYGIILPFALIG
LAGIIRRNLKPFDDFKRELTQRDSSDLSPIHDETYPEELLPTIEEMNRLFERISESQQEQKQFVADAAHELRTPITALNL
QTKILLSQFPDHAALQNLGKGLARIQHLVTQLLALAKQDVSLSSIERHTTFLLNDVTLNCVEQLMNMAMEKEIDLGFERN
EDIEMVSIEPTVHSIIFNLIDNAIKYTPAAGVINISVYQDEKAFACVQIEDSGAGIDPQYYDQVLKRFYRVHHHLEVGSG
LGLSIVDKATQRLGGELILAKSPELGGLSVLVRLPKFLKT

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=453, Percent_Identity=28.2560706401766, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1790551, Length=297, Percent_Identity=30.6397306397306, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788279, Length=254, Percent_Identity=30.3149606299213, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786600, Length=198, Percent_Identity=32.3232323232323, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1786783, Length=280, Percent_Identity=28.9285714285714, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790346, Length=253, Percent_Identity=25.296442687747, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788393, Length=251, Percent_Identity=26.6932270916335, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790861, Length=231, Percent_Identity=29.8701298701299, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081816, Length=238, Percent_Identity=28.9915966386555, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=27.3972602739726, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786912, Length=240, Percent_Identity=25.8333333333333, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1789149, Length=245, Percent_Identity=26.530612244898, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=24.7826086956522, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788549, Length=221, Percent_Identity=23.5294117647059, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50334; Mature: 50202

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQHYSLRRRLIWVTSIFSVLLGCVLVFTAYKVALHETNQILDEQMRYLADRTARQPLYN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VDSHFQANHEYHEEDLLVDIWAYDDQRHLQDENQLLIPPVKKAGFYSQETKQGILRAYVL
CCCHHCCCCCCCCCCEEEEEEECCCHHHCCCCCCEECCCCHHCCCCCHHHHHHHHHHHHC
PLEDYQIQVSQLEKVRKVVALELAASMFLPYGIILPFALIGLAGIIRRNLKPFDDFKREL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TQRDSSDLSPIHDETYPEELLPTIEEMNRLFERISESQQEQKQFVADAAHELRTPITALN
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LQTKILLSQFPDHAALQNLGKGLARIQHLVTQLLALAKQDVSLSSIERHTTFLLNDVTLN
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
CVEQLMNMAMEKEIDLGFERNEDIEMVSIEPTVHSIIFNLIDNAIKYTPAAGVINISVYQ
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEEE
DEKAFACVQIEDSGAGIDPQYYDQVLKRFYRVHHHLEVGSGLGLSIVDKATQRLGGELIL
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEE
AKSPELGGLSVLVRLPKFLKT
ECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQHYSLRRRLIWVTSIFSVLLGCVLVFTAYKVALHETNQILDEQMRYLADRTARQPLYN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VDSHFQANHEYHEEDLLVDIWAYDDQRHLQDENQLLIPPVKKAGFYSQETKQGILRAYVL
CCCHHCCCCCCCCCCEEEEEEECCCHHHCCCCCCEECCCCHHCCCCCHHHHHHHHHHHHC
PLEDYQIQVSQLEKVRKVVALELAASMFLPYGIILPFALIGLAGIIRRNLKPFDDFKREL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TQRDSSDLSPIHDETYPEELLPTIEEMNRLFERISESQQEQKQFVADAAHELRTPITALN
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LQTKILLSQFPDHAALQNLGKGLARIQHLVTQLLALAKQDVSLSSIERHTTFLLNDVTLN
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
CVEQLMNMAMEKEIDLGFERNEDIEMVSIEPTVHSIIFNLIDNAIKYTPAAGVINISVYQ
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEEE
DEKAFACVQIEDSGAGIDPQYYDQVLKRFYRVHHHLEVGSGLGLSIVDKATQRLGGELIL
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEE
AKSPELGGLSVLVRLPKFLKT
ECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]