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The map label for this gene is lolB [H]

Identifier: 50085936

GI number: 50085936

Start: 2842341

End: 2842922

Strand: Direct

Name: lolB [H]

Synonym: ACIAD2902

Alternate gene names: 50085936

Gene position: 2842341-2842922 (Clockwise)

Preceding gene: 50085935

Following gene: 50085937

Centisome position: 78.98

GC content: 41.07

Gene sequence:

>582_bases
ATGTTTAAAACATCTCAACTTTCAATCGCATTATGCTGTACAAGTGCTTTATTGTTTAGCGGCTGTCAACACATTATAAA
ACCTCAGTCAGCACCGAGTACAGCTCAAGCTGAACAACCTAATGAATTTGATTTACAAGGTAAAATTGGTGTACGCACAC
CTCAACAATCTGGAAGTGCCTTTTTTACGTGGTCACAGCATCAAGATGATTTTGATATCGAGCTCAGCGGTATCCTGGGC
GTAGGTAAAACACAAATTGAGGGCAAACCAGGTGAAGTCACTCTAAATAGTGCCAAGACTGGCTTAATTACCGCCTCCAG
CCCAGAAGAACTACTAAAACGTGCAACAGGCTGGGATGCACCCATCACCCATATCGTAAGCTGGGTACAAGCTAAGCCAG
CAACACTTTTAGCAAAAACCATGCAAGATGATCAGGGTCGAATCAAGGATATTCAGGAAGATGGCTGGAATGTCAATCTA
AGTTATAATGCCCAGCAAACTCTTCCCAATAAACTGATTTTAAAGCAGTCACTTGCAGATAATCAGGAAAACCGTATTAC
AATGATTATTCAAAATCGTTAA

Upstream 100 bases:

>100_bases
CGAAGTGTTACAACAGCTCAAAGAAAAAAATGCAAATGATCCACAATTAAAACAGCTTGATGCGTTAATTTTACCGACAG
TGACTAAAAAGAGTTAATTT

Downstream 100 bases:

>100_bases
GTCAAGTTGGGTTTATGATTCGTGTAGCATCCCCTGCCAAAATTAATTTATTTTTGCATATTACAGGCCGTCGTAATGAC
GGCTATCACGAGTTACAAAG

Product: outer-membrane lipoprotein precursor

Products: 5-aminolevulinate; CoA; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MFKTSQLSIALCCTSALLFSGCQHIIKPQSAPSTAQAEQPNEFDLQGKIGVRTPQQSGSAFFTWSQHQDDFDIELSGILG
VGKTQIEGKPGEVTLNSAKTGLITASSPEELLKRATGWDAPITHIVSWVQAKPATLLAKTMQDDQGRIKDIQEDGWNVNL
SYNAQQTLPNKLILKQSLADNQENRITMIIQNR

Sequences:

>Translated_193_residues
MFKTSQLSIALCCTSALLFSGCQHIIKPQSAPSTAQAEQPNEFDLQGKIGVRTPQQSGSAFFTWSQHQDDFDIELSGILG
VGKTQIEGKPGEVTLNSAKTGLITASSPEELLKRATGWDAPITHIVSWVQAKPATLLAKTMQDDQGRIKDIQEDGWNVNL
SYNAQQTLPNKLILKQSLADNQENRITMIIQNR
>Mature_193_residues
MFKTSQLSIALCCTSALLFSGCQHIIKPQSAPSTAQAEQPNEFDLQGKIGVRTPQQSGSAFFTWSQHQDDFDIELSGILG
VGKTQIEGKPGEVTLNSAKTGLITASSPEELLKRATGWDAPITHIVSWVQAKPATLLAKTMQDDQGRIKDIQEDGWNVNL
SYNAQQTLPNKLILKQSLADNQENRITMIIQNR

Specific function: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein [H]

COG id: COG3017

COG function: function code M; Outer membrane lipoprotein involved in outer membrane biogenesis

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004565 [H]

Pfam domain/function: PF03550 LolB [H]

EC number: NA

Molecular weight: Translated: 21179; Mature: 21179

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKTSQLSIALCCTSALLFSGCQHIIKPQSAPSTAQAEQPNEFDLQGKIGVRTPQQSGSA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCE
FFTWSQHQDDFDIELSGILGVGKTQIEGKPGEVTLNSAKTGLITASSPEELLKRATGWDA
EEEECCCCCCCCEEEEEEEECCCEEECCCCCEEEECCCCCEEEECCCHHHHHHHHCCCCC
PITHIVSWVQAKPATLLAKTMQDDQGRIKDIQEDGWNVNLSYNAQQTLPNKLILKQSLAD
CHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHCC
NQENRITMIIQNR
CCCCEEEEEEECC
>Mature Secondary Structure
MFKTSQLSIALCCTSALLFSGCQHIIKPQSAPSTAQAEQPNEFDLQGKIGVRTPQQSGSA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCE
FFTWSQHQDDFDIELSGILGVGKTQIEGKPGEVTLNSAKTGLITASSPEELLKRATGWDA
EEEECCCCCCCCEEEEEEEECCCEEECCCCCEEEECCCCCEEEECCCHHHHHHHHCCCCC
PITHIVSWVQAKPATLLAKTMQDDQGRIKDIQEDGWNVNLSYNAQQTLPNKLILKQSLAD
CHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHCC
NQENRITMIIQNR
CCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Succinyl-CoA; glycine [C]

Specific reaction: Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA