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The map label for this gene is coaD

Identifier: 50085927

GI number: 50085927

Start: 2832530

End: 2833021

Strand: Reverse

Name: coaD

Synonym: ACIAD2893

Alternate gene names: 50085927

Gene position: 2833021-2832530 (Counterclockwise)

Preceding gene: 50085929

Following gene: 50085926

Centisome position: 78.73

GC content: 41.26

Gene sequence:

>492_bases
ATGTCTAAAACACGTGTTATTTATCCAGGCACATTTGATCCTATTACTAATGGTCATGTAGATTTAGTCACCCGTGCATC
AAGAATGTTTGATGAGGTTGTGGTTGCAATTGCAATCGGGCATCATAAAAAACCTCTTTTTAGTTTAGAAGAACGCGTCA
AGCTGGCTCAGTTATCATTGAGTCACTTGCACAATGTGGAATTTGTTGGTTTTGATGGCTTGCTGGTCAATTTTTTTCGT
GAACAAAATGCAACGGCTGTTTTGCGTGGGTTGCGCGCCGTTTCCGATTTTGAGTATGAATTTCAACTGGCCAATATGAA
TCGTCAGCTTGATCATCATTTTGAAGCGGTATTTTTAACGCCTTCAGAACAGTACTCGTTTATTTCATCGACTCTGGTGC
GTGAAATTGCACGCCTAAGAGGTGATGTCGCCAAGTTTGTGCCTCAGGCTGTGGTTGAGGCTTTTGAATATAAACATCAA
CAAGGTTGGTAG

Upstream 100 bases:

>100_bases
ACGACCGAGGTGAAGTTTTTTCATTTTAATGGAGTGACTTCGCTAAGAAATCAAGATTTGCTAGAATTAAGACTTACACA
ATAAACTAGAGTACAACCGG

Downstream 100 bases:

>100_bases
CGTGTCATTATATATCACTGAAGAATGCATCAATTGTGATGTCTGTGAACCCGTGTGTCCCAATGAAGCCATCTATATGG
GTGAATTGATTTATGAAATT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MSKTRVIYPGTFDPITNGHVDLVTRASRMFDEVVVAIAIGHHKKPLFSLEERVKLAQLSLSHLHNVEFVGFDGLLVNFFR
EQNATAVLRGLRAVSDFEYEFQLANMNRQLDHHFEAVFLTPSEQYSFISSTLVREIARLRGDVAKFVPQAVVEAFEYKHQ
QGW

Sequences:

>Translated_163_residues
MSKTRVIYPGTFDPITNGHVDLVTRASRMFDEVVVAIAIGHHKKPLFSLEERVKLAQLSLSHLHNVEFVGFDGLLVNFFR
EQNATAVLRGLRAVSDFEYEFQLANMNRQLDHHFEAVFLTPSEQYSFISSTLVREIARLRGDVAKFVPQAVVEAFEYKHQ
QGW
>Mature_162_residues
SKTRVIYPGTFDPITNGHVDLVTRASRMFDEVVVAIAIGHHKKPLFSLEERVKLAQLSLSHLHNVEFVGFDGLLVNFFRE
QNATAVLRGLRAVSDFEYEFQLANMNRQLDHHFEAVFLTPSEQYSFISSTLVREIARLRGDVAKFVPQAVVEAFEYKHQQ
GW

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=156, Percent_Identity=60.8974358974359, Blast_Score=202, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_ACIAD (Q6F8K0)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047437.1
- ProteinModelPortal:   Q6F8K0
- SMR:   Q6F8K0
- STRING:   Q6F8K0
- GeneID:   2877934
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD2893
- NMPDR:   fig|62977.3.peg.2630
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q6F8K0
- ProtClustDB:   PRK00168
- BioCyc:   ASP62977:ACIAD2893-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18679; Mature: 18547

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTRVIYPGTFDPITNGHVDLVTRASRMFDEVVVAIAIGHHKKPLFSLEERVKLAQLSL
CCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SHLHNVEFVGFDGLLVNFFREQNATAVLRGLRAVSDFEYEFQLANMNRQLDHHFEAVFLT
HHHCCCEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCHHHHCCEEEEEEC
PSEQYSFISSTLVREIARLRGDVAKFVPQAVVEAFEYKHQQGW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKTRVIYPGTFDPITNGHVDLVTRASRMFDEVVVAIAIGHHKKPLFSLEERVKLAQLSL
CCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SHLHNVEFVGFDGLLVNFFREQNATAVLRGLRAVSDFEYEFQLANMNRQLDHHFEAVFLT
HHHCCCEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCHHHHCCEEEEEEC
PSEQYSFISSTLVREIARLRGDVAKFVPQAVVEAFEYKHQQGW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA