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The map label for this gene is sucC

Identifier: 50085913

GI number: 50085913

Start: 2813447

End: 2814613

Strand: Reverse

Name: sucC

Synonym: ACIAD2873

Alternate gene names: 50085913

Gene position: 2814613-2813447 (Counterclockwise)

Preceding gene: 50085914

Following gene: 50085912

Centisome position: 78.21

GC content: 42.59

Gene sequence:

>1167_bases
ATGAACTTACATGAGTATCAAGCCAAAGCACTGTTGAAAAAATATGGAGTGTCTGTCCAAGAAGGAATTTTGGCAAGAAG
TGCAGAAGAAGCAGTCGCTGCATTTGAACAATTAGGTGGCAAATTTGCTGTGATCAAAGCGCAGGTACATGCGGGTGGTC
GTGGTAAGGCAGGTGGTGTAAAAGTTGTTAAATCAAAAGAAGAAGCCGCTGATTATGCAAACCAGTTGATTGGTACCAAT
CTTGTGACCTATCAGACGGATGCGAATGGACAACCAGTCAATAGCGTCCTTGTTTGCGAAGATGTATATCCTGTTGAGCG
TGAACTGTATCTCGGTGCTGTGGTCGACCGTTCCTCACGCCGTGTGACGTTCATGGCATCCACTGAAGGTGGGGTGGAAA
TTGAGAAAGTTGCTGAAGAAACACCAGAAAAAATTATCAAAGTTGAAGTGGATCCACTTGTAGGTTTACAACCGTTTCAA
GCGCGTGAAGTTGCTTTTGCATTAGGTTTAAAAGACAAGCAGATTGGTCAGTTTGTCAAGCTGATGGCAGGTGCTTATCA
GGCATTCGTTGAAAATGATTTTGCCCTATTTGAAATCAACCCACTCTCAGTTCGTGAAAACGGCGATATTCTTGCAGTCG
ATGCTAAAATTGGAATCGATTCAAATGCATTGTACCGTTTGCCTGAAATCGCAGCATCTCGTGACAAGTCACAAGAAAAC
GAGCGTGAATTAAAAGCGTCTGAGTTTGAACTGAATTACGTTGCGCTTGAAGGGAATATTGGTTGTATGGTCAATGGTGC
TGGTCTGGCTATGGCAACCATGGACATTATTAAACTTTATGGCGGTCAACCTGCAAACTTCCTTGACGTAGGTGGTGGTG
CAACCAAAGAGCGTGTAATTGAAGCGTTTAAACTCATTTTAGCCGATACATCTGTACAAGGTGTATTGATTAATATCTTC
GGTGGAATTGTGCGTTGTGACATGATTGCTGAAGCAATTATTGCAGCAGTTCAAGAGGTTAATGTGACTGTTCCTGTTGT
TGTCCGTTTAGAGGGTAATAATGCAGAACTAGGCGCAAAAATTCTCGATGAATCTGGTTTAAAACTTACTTCTGCTAATG
GTTTATCCGATGCGGCAGAAAAAATTGTTGCTGCAGTGAAAGGGTAA

Upstream 100 bases:

>100_bases
AAGTACAAACGAAATTGAAAAAATGATCTGTATTTACTGAGATGGATGTTTAAGTACGGGTCAGTTATAACTAAGGGCAC
AAGTAGTAAAAGGTAACTAA

Downstream 100 bases:

>100_bases
GGGAGTATTCAGCATGAGCGTTTTAATTAATAAAGACACAAAAGTATTGGTACAAGGTTTTACTGGTAAAAATGGTACTT
TCCATTCAGCACAAGCTTTA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKALLKKYGVSVQEGILARSAEEAVAAFEQLGGKFAVIKAQVHAGGRGKAGGVKVVKSKEEAADYANQLIGTN
LVTYQTDANGQPVNSVLVCEDVYPVERELYLGAVVDRSSRRVTFMASTEGGVEIEKVAEETPEKIIKVEVDPLVGLQPFQ
AREVAFALGLKDKQIGQFVKLMAGAYQAFVENDFALFEINPLSVRENGDILAVDAKIGIDSNALYRLPEIAASRDKSQEN
ERELKASEFELNYVALEGNIGCMVNGAGLAMATMDIIKLYGGQPANFLDVGGGATKERVIEAFKLILADTSVQGVLINIF
GGIVRCDMIAEAIIAAVQEVNVTVPVVVRLEGNNAELGAKILDESGLKLTSANGLSDAAEKIVAAVKG

Sequences:

>Translated_388_residues
MNLHEYQAKALLKKYGVSVQEGILARSAEEAVAAFEQLGGKFAVIKAQVHAGGRGKAGGVKVVKSKEEAADYANQLIGTN
LVTYQTDANGQPVNSVLVCEDVYPVERELYLGAVVDRSSRRVTFMASTEGGVEIEKVAEETPEKIIKVEVDPLVGLQPFQ
AREVAFALGLKDKQIGQFVKLMAGAYQAFVENDFALFEINPLSVRENGDILAVDAKIGIDSNALYRLPEIAASRDKSQEN
ERELKASEFELNYVALEGNIGCMVNGAGLAMATMDIIKLYGGQPANFLDVGGGATKERVIEAFKLILADTSVQGVLINIF
GGIVRCDMIAEAIIAAVQEVNVTVPVVVRLEGNNAELGAKILDESGLKLTSANGLSDAAEKIVAAVKG
>Mature_388_residues
MNLHEYQAKALLKKYGVSVQEGILARSAEEAVAAFEQLGGKFAVIKAQVHAGGRGKAGGVKVVKSKEEAADYANQLIGTN
LVTYQTDANGQPVNSVLVCEDVYPVERELYLGAVVDRSSRRVTFMASTEGGVEIEKVAEETPEKIIKVEVDPLVGLQPFQ
AREVAFALGLKDKQIGQFVKLMAGAYQAFVENDFALFEINPLSVRENGDILAVDAKIGIDSNALYRLPEIAASRDKSQEN
ERELKASEFELNYVALEGNIGCMVNGAGLAMATMDIIKLYGGQPANFLDVGGGATKERVIEAFKLILADTSVQGVLINIF
GGIVRCDMIAEAIIAAVQEVNVTVPVVVRLEGNNAELGAKILDESGLKLTSANGLSDAAEKIVAAVKG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=47.4358974358974, Blast_Score=345, Evalue=3e-95,
Organism=Homo sapiens, GI157779135, Length=388, Percent_Identity=44.8453608247423, Blast_Score=301, Evalue=7e-82,
Organism=Homo sapiens, GI294862256, Length=367, Percent_Identity=44.4141689373297, Blast_Score=281, Evalue=6e-76,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=63.659793814433, Blast_Score=480, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=43.9588688946015, Blast_Score=323, Evalue=7e-89,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=43.2911392405063, Blast_Score=319, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=43.765903307888, Blast_Score=329, Evalue=6e-91,
Organism=Drosophila melanogaster, GI21356231, Length=398, Percent_Identity=44.2211055276382, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI161078106, Length=387, Percent_Identity=42.8940568475452, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI24645208, Length=387, Percent_Identity=42.8940568475452, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI281361397, Length=388, Percent_Identity=43.0412371134021, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI281361395, Length=388, Percent_Identity=43.0412371134021, Blast_Score=296, Evalue=1e-80,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_ACIAD (Q6F8L4)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047423.1
- ProteinModelPortal:   Q6F8L4
- STRING:   Q6F8L4
- GeneID:   2879236
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD2873
- NMPDR:   fig|62977.3.peg.2616
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   NPLIVMK
- PhylomeDB:   Q6F8L4
- ProtClustDB:   PRK00696
- BioCyc:   ASP62977:ACIAD2873-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41376; Mature: 41376

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKALLKKYGVSVQEGILARSAEEAVAAFEQLGGKFAVIKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KVVKSKEEAADYANQLIGTNLVTYQTDANGQPVNSVLVCEDVYPVERELYLGAVVDRSSR
EEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCHHEEEEEEEECCCC
RVTFMASTEGGVEIEKVAEETPEKIIKVEVDPLVGLQPFQAREVAFALGLKDKQIGQFVK
EEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHEEECCCHHHHHHHHH
LMAGAYQAFVENDFALFEINPLSVRENGDILAVDAKIGIDSNALYRLPEIAASRDKSQEN
HHHHHHHHHHCCCEEEEEECCEEEECCCCEEEEEEEECCCCCHHEECHHHHHCCCCCCHH
ERELKASEFELNYVALEGNIGCMVNGAGLAMATMDIIKLYGGQPANFLDVGGGATKERVI
HHHHCCCEEEEEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHH
EAFKLILADTSVQGVLINIFGGIVRCDMIAEAIIAAVQEVNVTVPVVVRLEGNNAELGAK
HHHHHHHCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHH
ILDESGLKLTSANGLSDAAEKIVAAVKG
HHCCCCCEEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNLHEYQAKALLKKYGVSVQEGILARSAEEAVAAFEQLGGKFAVIKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KVVKSKEEAADYANQLIGTNLVTYQTDANGQPVNSVLVCEDVYPVERELYLGAVVDRSSR
EEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCHHEEEEEEEECCCC
RVTFMASTEGGVEIEKVAEETPEKIIKVEVDPLVGLQPFQAREVAFALGLKDKQIGQFVK
EEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHEEECCCHHHHHHHHH
LMAGAYQAFVENDFALFEINPLSVRENGDILAVDAKIGIDSNALYRLPEIAASRDKSQEN
HHHHHHHHHHCCCEEEEEECCEEEECCCCEEEEEEEECCCCCHHEECHHHHHCCCCCCHH
ERELKASEFELNYVALEGNIGCMVNGAGLAMATMDIIKLYGGQPANFLDVGGGATKERVI
HHHHCCCEEEEEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHH
EAFKLILADTSVQGVLINIFGGIVRCDMIAEAIIAAVQEVNVTVPVVVRLEGNNAELGAK
HHHHHHHCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHH
ILDESGLKLTSANGLSDAAEKIVAAVKG
HHCCCCCEEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA