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The map label for this gene is sucD [H]

Identifier: 50085912

GI number: 50085912

Start: 2812543

End: 2813433

Strand: Reverse

Name: sucD [H]

Synonym: ACIAD2872

Alternate gene names: 50085912

Gene position: 2813433-2812543 (Counterclockwise)

Preceding gene: 50085913

Following gene: 50085910

Centisome position: 78.18

GC content: 41.64

Gene sequence:

>891_bases
ATGAGCGTTTTAATTAATAAAGACACAAAAGTATTGGTACAAGGTTTTACTGGTAAAAATGGTACTTTCCATTCAGCACA
AGCTTTAGATTACGGCACAAAAGTAGTCGGTGGTGTTACACCAGGCAAGGGTGGTACAACTCATCTTGACTTACCCGTTT
TTAATACCATGAAAGATGCTGTACGTGAAACAGGTGCAGATGCATCTGTCATTTATGTTCCAGCACCATTTGTACTTGAT
TCAATTGTTGAAGCGGTTGATTCTGGCGTCGGTCTTATTGTTGTGATTACCGAAGGTGTTCCAACTTTAGATATGCTTAA
AGCCAAGCGTTATCTTGAAACCAATGGGAATGGAACTCGTTTGGTTGGACCAAACTGTCCAGGGGTAATTACACCAGGTG
AATGTAAAATTGGAATTATGCCAGGTCATATTCATCAACCAGGGCGTATTGGAATTATTTCACGTTCGGGTACATTAACC
TATGAAGCTGTGGCTCAAACCACTAAGCTTGGTTTAGGTCAGTCGACGTGTATTGGTATTGGTGGTGATCCAATTCCAGG
CATGAATCAAATTGATGCGTTGAAGTTGTTCCAAGATGATCCAGATACAGATGCCATCATTATGATTGGTGAGATTGGTG
GTACAGCAGAAGAAGAAGCTGCTGAATATATCCAGTCCAATGTAACCAAACCTGTTGTTGGTTATATCGCAGGTGTAACT
GCACCAAAAGGTAAACGTATGGGACATGCAGGCGCAATTATTTCGGGCGGTAAAGGAACAGCAGAAGAGAAATTTGCTGC
ATTTGAACGTGCTGGCATGGCATATACGCGTAGCCCTGCGGAATTGGGTTCAACGATGTTGCAAGTATTAAAAGAGAAAG
GTTTAGCTTAA

Upstream 100 bases:

>100_bases
ATTCTCGATGAATCTGGTTTAAAACTTACTTCTGCTAATGGTTTATCCGATGCGGCAGAAAAAATTGTTGCTGCAGTGAA
AGGGTAAGGGAGTATTCAGC

Downstream 100 bases:

>100_bases
TTTCTTAGCAAAATCTAAAAGCCCCTTATTCACTTGATCAAAATTTGGATAAATTCCTTTTTTGATATGAATAAGGGGCT
TTCTTTTTTTAGAAAACTAA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSVLINKDTKVLVQGFTGKNGTFHSAQALDYGTKVVGGVTPGKGGTTHLDLPVFNTMKDAVRETGADASVIYVPAPFVLD
SIVEAVDSGVGLIVVITEGVPTLDMLKAKRYLETNGNGTRLVGPNCPGVITPGECKIGIMPGHIHQPGRIGIISRSGTLT
YEAVAQTTKLGLGQSTCIGIGGDPIPGMNQIDALKLFQDDPDTDAIIMIGEIGGTAEEEAAEYIQSNVTKPVVGYIAGVT
APKGKRMGHAGAIISGGKGTAEEKFAAFERAGMAYTRSPAELGSTMLQVLKEKGLA

Sequences:

>Translated_296_residues
MSVLINKDTKVLVQGFTGKNGTFHSAQALDYGTKVVGGVTPGKGGTTHLDLPVFNTMKDAVRETGADASVIYVPAPFVLD
SIVEAVDSGVGLIVVITEGVPTLDMLKAKRYLETNGNGTRLVGPNCPGVITPGECKIGIMPGHIHQPGRIGIISRSGTLT
YEAVAQTTKLGLGQSTCIGIGGDPIPGMNQIDALKLFQDDPDTDAIIMIGEIGGTAEEEAAEYIQSNVTKPVVGYIAGVT
APKGKRMGHAGAIISGGKGTAEEKFAAFERAGMAYTRSPAELGSTMLQVLKEKGLA
>Mature_295_residues
SVLINKDTKVLVQGFTGKNGTFHSAQALDYGTKVVGGVTPGKGGTTHLDLPVFNTMKDAVRETGADASVIYVPAPFVLDS
IVEAVDSGVGLIVVITEGVPTLDMLKAKRYLETNGNGTRLVGPNCPGVITPGECKIGIMPGHIHQPGRIGIISRSGTLTY
EAVAQTTKLGLGQSTCIGIGGDPIPGMNQIDALKLFQDDPDTDAIIMIGEIGGTAEEEAAEYIQSNVTKPVVGYIAGVTA
PKGKRMGHAGAIISGGKGTAEEKFAAFERAGMAYTRSPAELGSTMLQVLKEKGLA

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=297, Percent_Identity=60.6060606060606, Blast_Score=319, Evalue=2e-87,
Organism=Homo sapiens, GI38569421, Length=262, Percent_Identity=30.5343511450382, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI38569423, Length=262, Percent_Identity=30.5343511450382, Blast_Score=105, Evalue=5e-23,
Organism=Escherichia coli, GI1786949, Length=291, Percent_Identity=72.1649484536082, Blast_Score=431, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17550194, Length=286, Percent_Identity=62.5874125874126, Blast_Score=337, Evalue=5e-93,
Organism=Caenorhabditis elegans, GI17553126, Length=293, Percent_Identity=60.4095563139932, Blast_Score=332, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI17551266, Length=323, Percent_Identity=29.7213622291022, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17557344, Length=320, Percent_Identity=28.125, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324716, Length=294, Percent_Identity=53.7414965986395, Blast_Score=291, Evalue=9e-80,
Organism=Drosophila melanogaster, GI21356559, Length=288, Percent_Identity=57.9861111111111, Blast_Score=343, Evalue=1e-94,
Organism=Drosophila melanogaster, GI28574296, Length=292, Percent_Identity=58.9041095890411, Blast_Score=319, Evalue=1e-87,
Organism=Drosophila melanogaster, GI281363477, Length=262, Percent_Identity=28.2442748091603, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281363475, Length=262, Percent_Identity=28.2442748091603, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281363473, Length=262, Percent_Identity=28.2442748091603, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30653; Mature: 30521

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLINKDTKVLVQGFTGKNGTFHSAQALDYGTKVVGGVTPGKGGTTHLDLPVFNTMKDA
CEEEECCCCEEEEEECCCCCCCCCCHHHHCCCCEEECCCCCCCCCCEEEECCHHHHHHHH
VRETGADASVIYVPAPFVLDSIVEAVDSGVGLIVVITEGVPTLDMLKAKRYLETNGNGTR
HHHCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCE
LVGPNCPGVITPGECKIGIMPGHIHQPGRIGIISRSGTLTYEAVAQTTKLGLGQSTCIGI
EECCCCCCEECCCCEEEEEECCCCCCCCEEEEEECCCCEEHHHHHHHHHCCCCCCEEEEC
GGDPIPGMNQIDALKLFQDDPDTDAIIMIGEIGGTAEEEAAEYIQSNVTKPVVGYIAGVT
CCCCCCCCCCHHHHHEECCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHCCC
APKGKRMGHAGAIISGGKGTAEEKFAAFERAGMAYTRSPAELGSTMLQVLKEKGLA
CCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVLINKDTKVLVQGFTGKNGTFHSAQALDYGTKVVGGVTPGKGGTTHLDLPVFNTMKDA
EEEECCCCEEEEEECCCCCCCCCCHHHHCCCCEEECCCCCCCCCCEEEECCHHHHHHHH
VRETGADASVIYVPAPFVLDSIVEAVDSGVGLIVVITEGVPTLDMLKAKRYLETNGNGTR
HHHCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCE
LVGPNCPGVITPGECKIGIMPGHIHQPGRIGIISRSGTLTYEAVAQTTKLGLGQSTCIGI
EECCCCCCEECCCCEEEEEECCCCCCCCEEEEEECCCCEEHHHHHHHHHCCCCCCEEEEC
GGDPIPGMNQIDALKLFQDDPDTDAIIMIGEIGGTAEEEAAEYIQSNVTKPVVGYIAGVT
CCCCCCCCCCHHHHHEECCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHCCC
APKGKRMGHAGAIISGGKGTAEEKFAAFERAGMAYTRSPAELGSTMLQVLKEKGLA
CCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]