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The map label for this gene is trpS [H]

Identifier: 50085911

GI number: 50085911

Start: 2811122

End: 2812135

Strand: Direct

Name: trpS [H]

Synonym: ACIAD2871

Alternate gene names: 50085911

Gene position: 2811122-2812135 (Clockwise)

Preceding gene: 50085908

Following gene: 50085921

Centisome position: 78.12

GC content: 42.01

Gene sequence:

>1014_bases
ATGAGTAATGTTGATCAGCGTCCAATCATCTTGACAGGCGATCGCCCGACAGGACAACTTCATCTCGGGCATTTTGTGGG
TTCTTTACGTTCTCGCGTGGGTCTACAGGACAGTCATCATCAACATATTTTATTGGCAGATGCCCAAGCTTTAACAGATA
ACGCGGATAACCCAGATAAAGTCCGCCGTAATATTTTAGAAGTTGCACTGGATTATATGGCAGTTGGCATTGATCCATTA
AAGACCACTATCTGTGTGCAATCTTGCTTACCAGCACTCAATGAACTGACCATGCTGTATCTGAATTTTGTTACTGTGGC
ACGTCTTGAGCGCAACCCGACAATTAAGTCTGAAATTCAGATGCGCGGTTTTGAGCGTGATATTCCTGCAGGTTTCCTAT
GCTACCCAGTTGCCCAGGCAGCAGATATTACCGCTTTTAAAGCGACAGTCGTACCCGTCGGTGAAGATCAGATTCCAATG
ATCGAACAAACCAATGAGATTGTTCGTCGAGTTAATCGCCAGATTGGGCAAGATCTTTTACCTGAATGTAAAGCGCTACT
TTCCAATACAGGCCGCTTGCCTGGTTTTGATGGCAAAGCCAAAATGTCAAAATCTCTTGGAAATACCATTGTATTAAATG
CCACTGATAAAGATATTAAAAAAGCAGTGAATGCAATGTATACCGATCCAAACCACTTACGTATCGAAGATCCAGGTCAA
GTAGAAGGCAATATTGTATTTGCTTATTTAGATGCTTTCGATACCAACAAACAAGAAGTTGAAGAGCTCAAAGCACATTA
TCGCCGTGGTGGTTTAGGCGACGGTACAGTGAAAAAGCGTCTTGAAGGTATCTTAAAAGAGTTAATTATGCCAATTCGTG
AACGTCGTGAAGAACTTGCTAAGGATCCAGACTATATTATGGATGTGTTACGCGAAGGTACACTGAAATGCCAAAAAATT
ACTCAGCAGACACTGGACGAAGTAAAAGAAGGTTTAGGCTTATTTAAGTTCTGA

Upstream 100 bases:

>100_bases
TATCGCTGACGATTTTCCTTTATTTCCCGTACAATAACGCCAATCTTTTATATTACAGGGCACTTCCCCTGATTAAGCCA
ATACAATAGTGGGATAAATA

Downstream 100 bases:

>100_bases
TTAATAACCGTTCAATTAAACTTTATTACTCAAAAGATTTAACCTTGTGCGATCAATTGATCGCACTTTTATTTTGAGGT
TAAAGTTTATAATTTAATCG

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSNVDQRPIILTGDRPTGQLHLGHFVGSLRSRVGLQDSHHQHILLADAQALTDNADNPDKVRRNILEVALDYMAVGIDPL
KTTICVQSCLPALNELTMLYLNFVTVARLERNPTIKSEIQMRGFERDIPAGFLCYPVAQAADITAFKATVVPVGEDQIPM
IEQTNEIVRRVNRQIGQDLLPECKALLSNTGRLPGFDGKAKMSKSLGNTIVLNATDKDIKKAVNAMYTDPNHLRIEDPGQ
VEGNIVFAYLDAFDTNKQEVEELKAHYRRGGLGDGTVKKRLEGILKELIMPIRERREELAKDPDYIMDVLREGTLKCQKI
TQQTLDEVKEGLGLFKF

Sequences:

>Translated_337_residues
MSNVDQRPIILTGDRPTGQLHLGHFVGSLRSRVGLQDSHHQHILLADAQALTDNADNPDKVRRNILEVALDYMAVGIDPL
KTTICVQSCLPALNELTMLYLNFVTVARLERNPTIKSEIQMRGFERDIPAGFLCYPVAQAADITAFKATVVPVGEDQIPM
IEQTNEIVRRVNRQIGQDLLPECKALLSNTGRLPGFDGKAKMSKSLGNTIVLNATDKDIKKAVNAMYTDPNHLRIEDPGQ
VEGNIVFAYLDAFDTNKQEVEELKAHYRRGGLGDGTVKKRLEGILKELIMPIRERREELAKDPDYIMDVLREGTLKCQKI
TQQTLDEVKEGLGLFKF
>Mature_336_residues
SNVDQRPIILTGDRPTGQLHLGHFVGSLRSRVGLQDSHHQHILLADAQALTDNADNPDKVRRNILEVALDYMAVGIDPLK
TTICVQSCLPALNELTMLYLNFVTVARLERNPTIKSEIQMRGFERDIPAGFLCYPVAQAADITAFKATVVPVGEDQIPMI
EQTNEIVRRVNRQIGQDLLPECKALLSNTGRLPGFDGKAKMSKSLGNTIVLNATDKDIKKAVNAMYTDPNHLRIEDPGQV
EGNIVFAYLDAFDTNKQEVEELKAHYRRGGLGDGTVKKRLEGILKELIMPIRERREELAKDPDYIMDVLREGTLKCQKIT
QQTLDEVKEGLGLFKF

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=339, Percent_Identity=28.6135693215339, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI41352700, Length=185, Percent_Identity=32.4324324324324, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI1789786, Length=337, Percent_Identity=29.673590504451, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71982800, Length=353, Percent_Identity=27.4787535410765, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71982793, Length=353, Percent_Identity=27.4787535410765, Blast_Score=114, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6320474, Length=345, Percent_Identity=26.6666666666667, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24666151, Length=338, Percent_Identity=31.0650887573964, Blast_Score=133, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37685; Mature: 37554

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVDQRPIILTGDRPTGQLHLGHFVGSLRSRVGLQDSHHQHILLADAQALTDNADNPDK
CCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHCCCCCCHHH
VRRNILEVALDYMAVGIDPLKTTICVQSCLPALNELTMLYLNFVTVARLERNPTIKSEIQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MRGFERDIPAGFLCYPVAQAADITAFKATVVPVGEDQIPMIEQTNEIVRRVNRQIGQDLL
HCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
PECKALLSNTGRLPGFDGKAKMSKSLGNTIVLNATDKDIKKAVNAMYTDPNHLRIEDPGQ
HHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCEEEECCCCC
VEGNIVFAYLDAFDTNKQEVEELKAHYRRGGLGDGTVKKRLEGILKELIMPIRERREELA
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KDPDYIMDVLREGTLKCQKITQQTLDEVKEGLGLFKF
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SNVDQRPIILTGDRPTGQLHLGHFVGSLRSRVGLQDSHHQHILLADAQALTDNADNPDK
CCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHCCCCCCHHH
VRRNILEVALDYMAVGIDPLKTTICVQSCLPALNELTMLYLNFVTVARLERNPTIKSEIQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MRGFERDIPAGFLCYPVAQAADITAFKATVVPVGEDQIPMIEQTNEIVRRVNRQIGQDLL
HCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
PECKALLSNTGRLPGFDGKAKMSKSLGNTIVLNATDKDIKKAVNAMYTDPNHLRIEDPGQ
HHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCEEEECCCCC
VEGNIVFAYLDAFDTNKQEVEELKAHYRRGGLGDGTVKKRLEGILKELIMPIRERREELA
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KDPDYIMDVLREGTLKCQKITQQTLDEVKEGLGLFKF
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA