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The map label for this gene is yfdE [H]

Identifier: 50085867

GI number: 50085867

Start: 2758727

End: 2759926

Strand: Direct

Name: yfdE [H]

Synonym: ACIAD2821

Alternate gene names: 50085867

Gene position: 2758727-2759926 (Clockwise)

Preceding gene: 50085866

Following gene: 50085868

Centisome position: 76.66

GC content: 38.92

Gene sequence:

>1200_bases
ATGAGTATTGAAAAACCAAATAATCTTCCGCTATCAGGTATTCGTGTACTTGAATTTGTTCATATGGTTATGGGACCAGC
ATGTGGATTAATGTTGGCTGACCTTGGAGCCGAGGTTATTAAAATTGAACCAATACCTCAGGGCGATAATACACGTCGAT
TAATGGGATCGGGTGCTGGTTATTGGATGACCTATAATCGAAATAAAAAGAGCCTTTCAGTTGATATTAAAACTGAAAAA
GGAATGAATCTTGTCAAAGAGCTGATTGCTACTGCCGATATTGTGATTGAGAATTTTCGTCCAGGTGCAATGAAAAAACT
AGGCTTAGATTATGAAGGTGTCAAAGCCATTAAGCCTGACATTATTTATGGTTCTATGAAAGGCTTCTTACCTGGCCCTT
ATGAACATCGAACTGCACTTGATGAAGTTGTTCAAATGATGACAGGTCTAGCTTATATGACGGGTCCTGTGGGTCGACCT
TTAAGGGCTGGTGCTTCTGTTAATGATGTTATGGGTGGAATGTTCTGTGCTTATTCAATTCTTGCAGCCCTATATCAAAG
ACAATTGACAGGCGAAGGACAATTTGTCGAAACAGGATTATTTGAAAACTCTGCATTTTTAGTAGCGCAGCATATGATGC
AGCGAGCTGTAACTGAAAAACCTGTTGCACCAATGCCAAATCGTGTTTCAGCTTGGGCTGTATATGATGTATTTAATACG
CAAGGCAATGAGCAAGTATTTATTGGAGTTGTTACCGATTCTCAATGGTTAGCTTTCTGTGAAGCCTTCGATTTGAATAG
TCTTAAAAATAACCCAGATTATGCTCTAAATAATCAAAGAGTTAAAGCAAGAGATGTAATTTTGCCAATTATTCGAGATG
CATTAAGTGCGCTTGAAAAGTCAAAAGTGATGGAACTATGCGAACAAGCTGGGTTACCGTTCTCACCAATTCAACGTCCA
GAAGACTTATTCCATGATAATCACCTAAATCAGTCAGGTGGTATGGGTGAGCTCAAACTAGAAAATGGTAAGCAAGTCAA
AGTGCCCTTATTACCTTTTACAATGAATGGTCATCGATTTGGTGTACGTGAGAATGTGCCTCAAGTTGGTGAGAATACTG
TAGAAGTGCTTACATCATTAGGCTATGGCGCTGCTGAAGTACAGCTTTTAACTGAAACTGAGATTATTAAATGTAGCTAA

Upstream 100 bases:

>100_bases
AGAGAGTGGTTAAAAAAAGCATTACCAAATGAACCGCTATATGGATTCATCCCTGATGCGGGTGTAGGTAAAGCTTTTAA
ATATGCAAAGGATATGTGAA

Downstream 100 bases:

>100_bases
TGATTGGCTATTTAATTTGTGTATTATGCAAGGACTGCATATATGAATACTTTAAATAAACTCCCAGATAATTGTAATTT
GTCTCATCAAGAGGCTTGTG

Product: acyl-CoA transferase/carnitine dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSIEKPNNLPLSGIRVLEFVHMVMGPACGLMLADLGAEVIKIEPIPQGDNTRRLMGSGAGYWMTYNRNKKSLSVDIKTEK
GMNLVKELIATADIVIENFRPGAMKKLGLDYEGVKAIKPDIIYGSMKGFLPGPYEHRTALDEVVQMMTGLAYMTGPVGRP
LRAGASVNDVMGGMFCAYSILAALYQRQLTGEGQFVETGLFENSAFLVAQHMMQRAVTEKPVAPMPNRVSAWAVYDVFNT
QGNEQVFIGVVTDSQWLAFCEAFDLNSLKNNPDYALNNQRVKARDVILPIIRDALSALEKSKVMELCEQAGLPFSPIQRP
EDLFHDNHLNQSGGMGELKLENGKQVKVPLLPFTMNGHRFGVRENVPQVGENTVEVLTSLGYGAAEVQLLTETEIIKCS

Sequences:

>Translated_399_residues
MSIEKPNNLPLSGIRVLEFVHMVMGPACGLMLADLGAEVIKIEPIPQGDNTRRLMGSGAGYWMTYNRNKKSLSVDIKTEK
GMNLVKELIATADIVIENFRPGAMKKLGLDYEGVKAIKPDIIYGSMKGFLPGPYEHRTALDEVVQMMTGLAYMTGPVGRP
LRAGASVNDVMGGMFCAYSILAALYQRQLTGEGQFVETGLFENSAFLVAQHMMQRAVTEKPVAPMPNRVSAWAVYDVFNT
QGNEQVFIGVVTDSQWLAFCEAFDLNSLKNNPDYALNNQRVKARDVILPIIRDALSALEKSKVMELCEQAGLPFSPIQRP
EDLFHDNHLNQSGGMGELKLENGKQVKVPLLPFTMNGHRFGVRENVPQVGENTVEVLTSLGYGAAEVQLLTETEIIKCS
>Mature_398_residues
SIEKPNNLPLSGIRVLEFVHMVMGPACGLMLADLGAEVIKIEPIPQGDNTRRLMGSGAGYWMTYNRNKKSLSVDIKTEKG
MNLVKELIATADIVIENFRPGAMKKLGLDYEGVKAIKPDIIYGSMKGFLPGPYEHRTALDEVVQMMTGLAYMTGPVGRPL
RAGASVNDVMGGMFCAYSILAALYQRQLTGEGQFVETGLFENSAFLVAQHMMQRAVTEKPVAPMPNRVSAWAVYDVFNTQ
GNEQVFIGVVTDSQWLAFCEAFDLNSLKNNPDYALNNQRVKARDVILPIIRDALSALEKSKVMELCEQAGLPFSPIQRPE
DLFHDNHLNQSGGMGELKLENGKQVKVPLLPFTMNGHRFGVRENVPQVGENTVEVLTSLGYGAAEVQLLTETEIIKCS

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=378, Percent_Identity=30.1587301587302, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI300863124, Length=325, Percent_Identity=32.6153846153846, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI300863126, Length=378, Percent_Identity=27.7777777777778, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI13376042, Length=325, Percent_Identity=28, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI266456254, Length=395, Percent_Identity=23.7974683544304, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI42794625, Length=396, Percent_Identity=23.989898989899, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI266458393, Length=205, Percent_Identity=30.7317073170732, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI266458397, Length=205, Percent_Identity=30.7317073170732, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI42822893, Length=122, Percent_Identity=32.7868852459016, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI266458395, Length=122, Percent_Identity=32.7868852459016, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI87082093, Length=313, Percent_Identity=31.3099041533546, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1788717, Length=418, Percent_Identity=28.9473684210526, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1786222, Length=200, Percent_Identity=29, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32564160, Length=249, Percent_Identity=26.1044176706827, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115535051, Length=204, Percent_Identity=25.4901960784314, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648431, Length=400, Percent_Identity=33.5, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24585488, Length=249, Percent_Identity=31.3253012048193, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 43917; Mature: 43786

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIEKPNNLPLSGIRVLEFVHMVMGPACGLMLADLGAEVIKIEPIPQGDNTRRLMGSGAG
CCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCCC
YWMTYNRNKKSLSVDIKTEKGMNLVKELIATADIVIENFRPGAMKKLGLDYEGVKAIKPD
EEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHCCCC
IIYGSMKGFLPGPYEHRTALDEVVQMMTGLAYMTGPVGRPLRAGASVNDVMGGMFCAYSI
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHH
LAALYQRQLTGEGQFVETGLFENSAFLVAQHMMQRAVTEKPVAPMPNRVSAWAVYDVFNT
HHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC
QGNEQVFIGVVTDSQWLAFCEAFDLNSLKNNPDYALNNQRVKARDVILPIIRDALSALEK
CCCCEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SKVMELCEQAGLPFSPIQRPEDLFHDNHLNQSGGMGELKLENGKQVKVPLLPFTMNGHRF
HHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEECCCCEEEEEEEEEEECCCEE
GVRENVPQVGENTVEVLTSLGYGAAEVQLLTETEIIKCS
CCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCEEEECC
>Mature Secondary Structure 
SIEKPNNLPLSGIRVLEFVHMVMGPACGLMLADLGAEVIKIEPIPQGDNTRRLMGSGAG
CCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCCC
YWMTYNRNKKSLSVDIKTEKGMNLVKELIATADIVIENFRPGAMKKLGLDYEGVKAIKPD
EEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHCCCC
IIYGSMKGFLPGPYEHRTALDEVVQMMTGLAYMTGPVGRPLRAGASVNDVMGGMFCAYSI
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHH
LAALYQRQLTGEGQFVETGLFENSAFLVAQHMMQRAVTEKPVAPMPNRVSAWAVYDVFNT
HHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC
QGNEQVFIGVVTDSQWLAFCEAFDLNSLKNNPDYALNNQRVKARDVILPIIRDALSALEK
CCCCEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SKVMELCEQAGLPFSPIQRPEDLFHDNHLNQSGGMGELKLENGKQVKVPLLPFTMNGHRF
HHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEECCCCEEEEEEEEEEECCCEE
GVRENVPQVGENTVEVLTSLGYGAAEVQLLTETEIIKCS
CCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]