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The map label for this gene is antA [H]

Identifier: 50085736

GI number: 50085736

Start: 2623093

End: 2624508

Strand: Direct

Name: antA [H]

Synonym: ACIAD2669

Alternate gene names: 50085736

Gene position: 2623093-2624508 (Clockwise)

Preceding gene: 50085732

Following gene: 50085737

Centisome position: 72.89

GC content: 44.21

Gene sequence:

>1416_bases
ATGACTGCACGTAACCTCGCCGAATGGCAAAATTTTGTACAAGGTTGTATCGATTTTCGCCCGAATGATGGTGTTTATCG
AATTGCTCGCGATATGTTTACCGAGCCTGAGTTATTTGAACTTGAAATGGAACTCATTTTTGAAAAGGTCTGGATCTACG
CCTGCCATGAAAGTGAAATCCCGAATAATAACGACTTCGTTACCGTACAGATTGGCCGCCAACCGATGATTGTGAGCCGT
GATGGTAAAGGCGAATTACATGCGATGGTCAATGCTTGCGAACATCGTGGTGCGACACTGACCCGAGTTGCCAAAGGCAA
TCAGTCGGTTTTTACCTGCCCATTTCATGCATGGTGCTACAAATCTGACGGTCGTTTAGTCAAGGTTAAAGCCCCTGGCG
AATACTGCGAAGATTTTGATAAATCAAGTCGCGGCTTAAAACAAGGGCGTATTGCCAGCTATCGTGGATTTGTGTTTGTC
AGTTTAGATACCCAAGCGACAGATTCTCTCGAAGACTTTTTAGGAGATGCCAAAGTATTTTTAGACCTGATGGTCGATCA
GTCTCCGACAGGTGAACTTGAAGTTCTGCAAGGTAAGTCTGCCTACACATTTGCAGGTAACTGGAAACTTCAAAATGAAA
ATGGCCTCGATGGCTACCACGTCAGTACCGTACATTATAACTATGTCTCTACTGTACAGCACCGCCAGCAAGTCAATGCA
GCCAAAGGCGATGAACTTGACACACTGGATTACAGCAAACTCGGTGCAGGTGATTCTGAAACCGATGATGGTTGGTTCAG
CTTTAAAAATGGTCACAGCGTACTGTTTAGTGATATGCCAAATCCAACCGTGCGTCCTGGCTACAATACTGTCATGCCGT
ACTTGGTGGAAAAGTTTGGCGAGAAACGTGCCGAATGGGCCATGCACCGTTTACGTAACTTGAATTTGTACCCAAGCCTG
TTCTTTATGGATCAGATCAGTTCTCAACTACGTATTATTCGCCCAGTGGCATGGAATAAAACTGAGGTGATTAGTCAGTG
TATTGGTGTTAAAGGCGAGTCTAGTGAAGCACGTCGTAACCGTATTCGCCAGTTTGAAGACTTCTTTAATGTTTCGGGTT
TAGGTACACCTGATGATCTGGTTGAATTTCGTGAACAACAAAAAGGATTTCAGGGACGTATCGAACGCTGGAGTGATATT
TCACGTGGTTACCATCAATGGACCTATGGCCCAACACAAAACTCGCAAGATTTAGGGATTGAGCCTGTGATTACTGGGCG
TGAATTTACTCACGAAGGTCTATATGTCAATCAACATGGACAGTGGCAACGTCTCATTTTGGATGGACTAAACAAAAAAG
CGCTCAAAATGCACGATGTTACTTTTGACAATCAATCTGTTATGGATGAGGTGTAA

Upstream 100 bases:

>100_bases
ACTGCATAAAGTGGATAAAGACAAGGAAAATCTGGATAGAGCACTTCTCAAATTCGCGGTTCAATCAGACAAAAGCACTG
ATTGGATAGAGGAAGAGCCC

Downstream 100 bases:

>100_bases
TCATGTCTCTCGAACTTCATTTTGCAGTTTCACAGTTCCTCTATAAAAAAGCAGAACTATGCGACAACTACGATTGGGAT
GCTTACATCGATTTATATGA

Product: anthranilate dioxygenase large subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MTARNLAEWQNFVQGCIDFRPNDGVYRIARDMFTEPELFELEMELIFEKVWIYACHESEIPNNNDFVTVQIGRQPMIVSR
DGKGELHAMVNACEHRGATLTRVAKGNQSVFTCPFHAWCYKSDGRLVKVKAPGEYCEDFDKSSRGLKQGRIASYRGFVFV
SLDTQATDSLEDFLGDAKVFLDLMVDQSPTGELEVLQGKSAYTFAGNWKLQNENGLDGYHVSTVHYNYVSTVQHRQQVNA
AKGDELDTLDYSKLGAGDSETDDGWFSFKNGHSVLFSDMPNPTVRPGYNTVMPYLVEKFGEKRAEWAMHRLRNLNLYPSL
FFMDQISSQLRIIRPVAWNKTEVISQCIGVKGESSEARRNRIRQFEDFFNVSGLGTPDDLVEFREQQKGFQGRIERWSDI
SRGYHQWTYGPTQNSQDLGIEPVITGREFTHEGLYVNQHGQWQRLILDGLNKKALKMHDVTFDNQSVMDEV

Sequences:

>Translated_471_residues
MTARNLAEWQNFVQGCIDFRPNDGVYRIARDMFTEPELFELEMELIFEKVWIYACHESEIPNNNDFVTVQIGRQPMIVSR
DGKGELHAMVNACEHRGATLTRVAKGNQSVFTCPFHAWCYKSDGRLVKVKAPGEYCEDFDKSSRGLKQGRIASYRGFVFV
SLDTQATDSLEDFLGDAKVFLDLMVDQSPTGELEVLQGKSAYTFAGNWKLQNENGLDGYHVSTVHYNYVSTVQHRQQVNA
AKGDELDTLDYSKLGAGDSETDDGWFSFKNGHSVLFSDMPNPTVRPGYNTVMPYLVEKFGEKRAEWAMHRLRNLNLYPSL
FFMDQISSQLRIIRPVAWNKTEVISQCIGVKGESSEARRNRIRQFEDFFNVSGLGTPDDLVEFREQQKGFQGRIERWSDI
SRGYHQWTYGPTQNSQDLGIEPVITGREFTHEGLYVNQHGQWQRLILDGLNKKALKMHDVTFDNQSVMDEV
>Mature_470_residues
TARNLAEWQNFVQGCIDFRPNDGVYRIARDMFTEPELFELEMELIFEKVWIYACHESEIPNNNDFVTVQIGRQPMIVSRD
GKGELHAMVNACEHRGATLTRVAKGNQSVFTCPFHAWCYKSDGRLVKVKAPGEYCEDFDKSSRGLKQGRIASYRGFVFVS
LDTQATDSLEDFLGDAKVFLDLMVDQSPTGELEVLQGKSAYTFAGNWKLQNENGLDGYHVSTVHYNYVSTVQHRQQVNAA
KGDELDTLDYSKLGAGDSETDDGWFSFKNGHSVLFSDMPNPTVRPGYNTVMPYLVEKFGEKRAEWAMHRLRNLNLYPSLF
FMDQISSQLRIIRPVAWNKTEVISQCIGVKGESSEARRNRIRQFEDFFNVSGLGTPDDLVEFREQQKGFQGRIERWSDIS
RGYHQWTYGPTQNSQDLGIEPVITGREFTHEGLYVNQHGQWQRLILDGLNKKALKMHDVTFDNQSVMDEV

Specific function: Degradation of benzoate to 2-hydro-1,2-dihydroxybenzoate (DHB) [H]

COG id: COG4638

COG function: function code PR; Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Rieske domain [H]

Homologues:

Organism=Escherichia coli, GI1788888, Length=387, Percent_Identity=30.4909560723514, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1788103, Length=254, Percent_Identity=31.496062992126, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017639
- InterPro:   IPR017941
- InterPro:   IPR015881
- InterPro:   IPR015879
- InterPro:   IPR001663 [H]

Pfam domain/function: PF00355 Rieske; PF00848 Ring_hydroxyl_A [H]

EC number: =1.14.12.10 [H]

Molecular weight: Translated: 53937; Mature: 53806

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00570 RING_HYDROXYL_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARNLAEWQNFVQGCIDFRPNDGVYRIARDMFTEPELFELEMELIFEKVWIYACHESEI
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCC
PNNNDFVTVQIGRQPMIVSRDGKGELHAMVNACEHRGATLTRVAKGNQSVFTCPFHAWCY
CCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEEECCEEEEE
KSDGRLVKVKAPGEYCEDFDKSSRGLKQGRIASYRGFVFVSLDTQATDSLEDFLGDAKVF
CCCCEEEEEECCHHHHHHHHHHHCCHHCCCCEEECCEEEEEECCCCHHHHHHHHCHHHHH
LDLMVDQSPTGELEVLQGKSAYTFAGNWKLQNENGLDGYHVSTVHYNYVSTVQHRQQVNA
HHHHCCCCCCCCEEEEECCCEEEEECCEEECCCCCCCCEEEEEEEEHHHHHHHHHHHHCC
AKGDELDTLDYSKLGAGDSETDDGWFSFKNGHSVLFSDMPNPTVRPGYNTVMPYLVEKFG
CCCCCCCCCCHHHCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
EKRAEWAMHRLRNLNLYPSLFFMDQISSQLRIIRPVAWNKTEVISQCIGVKGESSEARRN
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCCCCCCHHHHH
RIRQFEDFFNVSGLGTPDDLVEFREQQKGFQGRIERWSDISRGYHQWTYGPTQNSQDLGI
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
EPVITGREFTHEGLYVNQHGQWQRLILDGLNKKALKMHDVTFDNQSVMDEV
CEEECCCCCCCCCEEECCCCCHHHHHHHCCCCCCEEEEEECCCCHHHHHCC
>Mature Secondary Structure 
TARNLAEWQNFVQGCIDFRPNDGVYRIARDMFTEPELFELEMELIFEKVWIYACHESEI
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCC
PNNNDFVTVQIGRQPMIVSRDGKGELHAMVNACEHRGATLTRVAKGNQSVFTCPFHAWCY
CCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEEECCEEEEE
KSDGRLVKVKAPGEYCEDFDKSSRGLKQGRIASYRGFVFVSLDTQATDSLEDFLGDAKVF
CCCCEEEEEECCHHHHHHHHHHHCCHHCCCCEEECCEEEEEECCCCHHHHHHHHCHHHHH
LDLMVDQSPTGELEVLQGKSAYTFAGNWKLQNENGLDGYHVSTVHYNYVSTVQHRQQVNA
HHHHCCCCCCCCEEEEECCCEEEEECCEEECCCCCCCCEEEEEEEEHHHHHHHHHHHHCC
AKGDELDTLDYSKLGAGDSETDDGWFSFKNGHSVLFSDMPNPTVRPGYNTVMPYLVEKFG
CCCCCCCCCCHHHCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
EKRAEWAMHRLRNLNLYPSLFFMDQISSQLRIIRPVAWNKTEVISQCIGVKGESSEARRN
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCCCCCCHHHHH
RIRQFEDFFNVSGLGTPDDLVEFREQQKGFQGRIERWSDISRGYHQWTYGPTQNSQDLGI
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
EPVITGREFTHEGLYVNQHGQWQRLILDGLNKKALKMHDVTFDNQSVMDEV
CEEECCCCCCCCCEEECCCCCHHHHHHHCCCCCCEEEEEECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1885518 [H]