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The map label for this gene is xerC [H]

Identifier: 50085725

GI number: 50085725

Start: 2611761

End: 2612678

Strand: Reverse

Name: xerC [H]

Synonym: ACIAD2657

Alternate gene names: 50085725

Gene position: 2612678-2611761 (Counterclockwise)

Preceding gene: 50085726

Following gene: 50085724

Centisome position: 72.6

GC content: 40.85

Gene sequence:

>918_bases
ATGTATAACAATCAGCAACTTTTAGCAATGTGGTTAAAAGAGCGCATGATTCAGAATCAGTCTGAGCATACGCTAAATGC
TTATCAAAGAGACTTAACCGACTTTTTTGATTTCTGTGAAAAACGAAAGCTGGAGTTGATGCAAGTTGAAGCCTCAGATT
TGCGCGAATATTTGGCGTATCGCGTGGAGCAGTCAAATCTAAGTAGTAGCAGTATTCAACGGCACCTTTCTTCAATCCGT
CAATTTATGAAGTGGGCGCAGCAAAGTCAGTTTCTCAATATGAATCCAGTTGAAGATTTTAAACTCAAACGGAAATCTCG
TCCTTTACCAGGCATGATTGACATTGAAACCGTGCACCAGATTCTGGATCAAACCGCACCAGAGGATGAGCTTGGTACAC
AGCTTTGGTTAAGAGATAAAGCAATATTGGAATTGTTATATTCGAGTGGATTACGTCTGGCAGAATTACAGGGTTTGAAA
CTGATTGATCTGGATTTTAATCGACAGTTATTACGAGTCACGGGGAAAGGTAATAAAACACGGGTGATTCCCTTTGGGAA
AAAGGCAAAGCAGAGTCTGATTGACTGGTTAAATGTGTACCGTTTATGGAAAGGACAATTCACCCAGCAAGATCCACTGT
TTGTATCACAAAATGGCGGTGCACTCACGCCGCGTCAAATTGAAAATCGAGTAAAACATCAGGCTTTACGTGCTGGTGTG
AATGTCGATTTACATCCGCATTTATTACGCCACTGCTTTGCCAGTCACATGTTATCGGCCAGTGGTGATTTACGTTCTGT
ACAGGAAATGCTGGGTCATTCCAATCTAAGCACTACTCAGATTTATACCCATATTGATTTTGATCATTTGGCACAAGTTT
ATGATCGTGCCCATCCAAGAGCACAAAAAATAAAGTAA

Upstream 100 bases:

>100_bases
TGGTCAGCATGATCTTGCAAACCAACACGCCAAGCAGGTTGCTGTTTGTGTATTAGACTATTTAAAAAGTATTGAATCTA
GGCTGGAGCGCTGAACAGTC

Downstream 100 bases:

>100_bases
TTAAAATGTAAAACGTCACAATCTGAACGGATCATCATCCTAAAATTCAGCATAAGATTTACAAAATATAAAACCTTACC
TGACTGACAATTTTGATCTC

Product: site-specific tyrosine recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MYNNQQLLAMWLKERMIQNQSEHTLNAYQRDLTDFFDFCEKRKLELMQVEASDLREYLAYRVEQSNLSSSSIQRHLSSIR
QFMKWAQQSQFLNMNPVEDFKLKRKSRPLPGMIDIETVHQILDQTAPEDELGTQLWLRDKAILELLYSSGLRLAELQGLK
LIDLDFNRQLLRVTGKGNKTRVIPFGKKAKQSLIDWLNVYRLWKGQFTQQDPLFVSQNGGALTPRQIENRVKHQALRAGV
NVDLHPHLLRHCFASHMLSASGDLRSVQEMLGHSNLSTTQIYTHIDFDHLAQVYDRAHPRAQKIK

Sequences:

>Translated_305_residues
MYNNQQLLAMWLKERMIQNQSEHTLNAYQRDLTDFFDFCEKRKLELMQVEASDLREYLAYRVEQSNLSSSSIQRHLSSIR
QFMKWAQQSQFLNMNPVEDFKLKRKSRPLPGMIDIETVHQILDQTAPEDELGTQLWLRDKAILELLYSSGLRLAELQGLK
LIDLDFNRQLLRVTGKGNKTRVIPFGKKAKQSLIDWLNVYRLWKGQFTQQDPLFVSQNGGALTPRQIENRVKHQALRAGV
NVDLHPHLLRHCFASHMLSASGDLRSVQEMLGHSNLSTTQIYTHIDFDHLAQVYDRAHPRAQKIK
>Mature_305_residues
MYNNQQLLAMWLKERMIQNQSEHTLNAYQRDLTDFFDFCEKRKLELMQVEASDLREYLAYRVEQSNLSSSSIQRHLSSIR
QFMKWAQQSQFLNMNPVEDFKLKRKSRPLPGMIDIETVHQILDQTAPEDELGTQLWLRDKAILELLYSSGLRLAELQGLK
LIDLDFNRQLLRVTGKGNKTRVIPFGKKAKQSLIDWLNVYRLWKGQFTQQDPLFVSQNGGALTPRQIENRVKHQALRAGV
NVDLHPHLLRHCFASHMLSASGDLRSVQEMLGHSNLSTTQIYTHIDFDHLAQVYDRAHPRAQKIK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=282, Percent_Identity=39.7163120567376, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1789261, Length=303, Percent_Identity=38.9438943894389, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1790768, Length=169, Percent_Identity=28.4023668639053, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790767, Length=165, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35595; Mature: 35595

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNNQQLLAMWLKERMIQNQSEHTLNAYQRDLTDFFDFCEKRKLELMQVEASDLREYLAY
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVEQSNLSSSSIQRHLSSIRQFMKWAQQSQFLNMNPVEDFKLKRKSRPLPGMIDIETVHQ
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEHHHHHH
ILDQTAPEDELGTQLWLRDKAILELLYSSGLRLAELQGLKLIDLDFNRQLLRVTGKGNKT
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHCCCEEEEECCCCEEEEEECCCCCE
RVIPFGKKAKQSLIDWLNVYRLWKGQFTQQDPLFVSQNGGALTPRQIENRVKHQALRAGV
EEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCC
NVDLHPHLLRHCFASHMLSASGDLRSVQEMLGHSNLSTTQIYTHIDFDHLAQVYDRAHPR
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCH
AQKIK
HHCCC
>Mature Secondary Structure
MYNNQQLLAMWLKERMIQNQSEHTLNAYQRDLTDFFDFCEKRKLELMQVEASDLREYLAY
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVEQSNLSSSSIQRHLSSIRQFMKWAQQSQFLNMNPVEDFKLKRKSRPLPGMIDIETVHQ
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEHHHHHH
ILDQTAPEDELGTQLWLRDKAILELLYSSGLRLAELQGLKLIDLDFNRQLLRVTGKGNKT
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHCCCEEEEECCCCEEEEEECCCCCE
RVIPFGKKAKQSLIDWLNVYRLWKGQFTQQDPLFVSQNGGALTPRQIENRVKHQALRAGV
EEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCC
NVDLHPHLLRHCFASHMLSASGDLRSVQEMLGHSNLSTTQIYTHIDFDHLAQVYDRAHPR
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCH
AQKIK
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA