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The map label for this gene is tolR [H]

Identifier: 50085690

GI number: 50085690

Start: 2573528

End: 2573974

Strand: Direct

Name: tolR [H]

Synonym: ACIAD2620

Alternate gene names: 50085690

Gene position: 2573528-2573974 (Clockwise)

Preceding gene: 50085689

Following gene: 50085691

Centisome position: 71.51

GC content: 40.27

Gene sequence:

>447_bases
ATGGCCATTCAGCGTTCTGGGCGCTTCGAGCGCATCAAAAAACCTTTAAAAAGTGACATGAATGTTGTGCCATACATTGA
TGTGATGCTGGTATTACTGGTCATTTTCATGGTCACTGCACCTATGATTACTAGCGGTATCAAAGTAGATTTACCTCAAG
CCAACAATACCCCCATTGAATCTAAAGAACCCGCAATTGTAACACTTGGTCAAGACGGCAATATCTATCTTCAATATAAA
GAACACAAAGAAGATCAAGTCACTCTTGCAGAACTCAAAACTATTTTGGGAGAAGCACAATCTCAAGCAGATGAGAGTAA
CCAGAAAATAACTGTATTGGTAAATGGTGAAAAATCCAGACCTTATGGAGATGTGGTTTCACTCATGTCGAGTTTGCAAG
AAGCAGGCTTGACTCAGGTTGGTCTACTCACTGAGCCTTTAAAGTAA

Upstream 100 bases:

>100_bases
CTAAAGGTGAAGCAATCTATTCTGATCGAGCACTTTTTGCCGAAGAAATGGTTGCTTTATTACAACGTCAGTCTGTGGGT
TCAACACAGGAAGATGCATA

Downstream 100 bases:

>100_bases
GTTATGAAGAATTTTCAGAAGCCCGCTTTTAAAGAAAAAACGATTGCGATCAGTTTTACGCTGGTTGTACATACAATTGC
AATCGTAGGCTTACTTTATT

Product: group A colicins tolerance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MAIQRSGRFERIKKPLKSDMNVVPYIDVMLVLLVIFMVTAPMITSGIKVDLPQANNTPIESKEPAIVTLGQDGNIYLQYK
EHKEDQVTLAELKTILGEAQSQADESNQKITVLVNGEKSRPYGDVVSLMSSLQEAGLTQVGLLTEPLK

Sequences:

>Translated_148_residues
MAIQRSGRFERIKKPLKSDMNVVPYIDVMLVLLVIFMVTAPMITSGIKVDLPQANNTPIESKEPAIVTLGQDGNIYLQYK
EHKEDQVTLAELKTILGEAQSQADESNQKITVLVNGEKSRPYGDVVSLMSSLQEAGLTQVGLLTEPLK
>Mature_147_residues
AIQRSGRFERIKKPLKSDMNVVPYIDVMLVLLVIFMVTAPMITSGIKVDLPQANNTPIESKEPAIVTLGQDGNIYLQYKE
HKEDQVTLAELKTILGEAQSQADESNQKITVLVNGEKSRPYGDVVSLMSSLQEAGLTQVGLLTEPLK

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family [H]

Homologues:

Organism=Escherichia coli, GI1789380, Length=128, Percent_Identity=34.375, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1786959, Length=136, Percent_Identity=37.5, Blast_Score=60, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014168
- InterPro:   IPR003400 [H]

Pfam domain/function: PF02472 ExbD [H]

EC number: NA

Molecular weight: Translated: 16312; Mature: 16181

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQRSGRFERIKKPLKSDMNVVPYIDVMLVLLVIFMVTAPMITSGIKVDLPQANNTPIE
CCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCC
SKEPAIVTLGQDGNIYLQYKEHKEDQVTLAELKTILGEAQSQADESNQKITVLVNGEKSR
CCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCC
PYGDVVSLMSSLQEAGLTQVGLLTEPLK
CHHHHHHHHHHHHHCCCCEECCCCCCCC
>Mature Secondary Structure 
AIQRSGRFERIKKPLKSDMNVVPYIDVMLVLLVIFMVTAPMITSGIKVDLPQANNTPIE
CCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCC
SKEPAIVTLGQDGNIYLQYKEHKEDQVTLAELKTILGEAQSQADESNQKITVLVNGEKSR
CCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCC
PYGDVVSLMSSLQEAGLTQVGLLTEPLK
CHHHHHHHHHHHHHCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]