Click here to switch to the map view.

The map label for this gene is tolQ [H]

Identifier: 50085689

GI number: 50085689

Start: 2572830

End: 2573528

Strand: Direct

Name: tolQ [H]

Synonym: ACIAD2619

Alternate gene names: 50085689

Gene position: 2572830-2573528 (Clockwise)

Preceding gene: 50085688

Following gene: 50085690

Centisome position: 71.49

GC content: 41.06

Gene sequence:

>699_bases
ATGGCAACACCGATCCAATCTTCATTGCACATTTCTGATCTTATTTTACAAGCAAGTCCTGTGGTACAGGCTGTAATGTT
GATCTTACTTTTAGCATCGATTTATAGTTGGTATCTGATTGCCAAGTTGCATCTGAGTTATAAAAAATCTGCCCAGCAGG
ATGAACATTTTCAAAAAATGTTTTGGTCTGGCGCAGAACTTAATACGCTTTATAACAATGCCCAACTCAATTCTAAACGT
ACTGGCTTAGAAGATATTTTCTATCATGGTTTAGGTGAGTTTTTTAAACTCAAAAAACGCCAAGCCACGTCCACTCAAAC
CATCGAAGGAACAGAGCGAATTTTGCGTGTGGGCCTTAGTCGTGATCAAAGTCAGCTCGAACAGGGTTTAGGCACTTTGG
CCAGTATTGGTTCTGTTGCACCTTACGTCGGTTTATTTGGTACGGTATGGGGCATTATGAATGCTTTTATTGGTTTAGCT
GCTGTGGATCAAGTAACGCTTGCAACTGTAGCACCAGGTATCGCGGAGGCCCTAATTGCAACAGCAATTGGTTTATTTGC
CGCAATTCCTGCAGTACTCGCTTTTAACCATTTTACTTCTAAAGGTGAAGCAATCTATTCTGATCGAGCACTTTTTGCCG
AAGAAATGGTTGCTTTATTACAACGTCAGTCTGTGGGTTCAACACAGGAAGATGCATAA

Upstream 100 bases:

>100_bases
AACGCTGAATTACGTCCTCGTCGTTTGCCAGATGAAATTCGTGATCTTATTCTGAAAGAATTAGAACAGGCTTAAAAAAC
ACACTTTGGCATTTGTAACT

Downstream 100 bases:

>100_bases
TGGCCATTCAGCGTTCTGGGCGCTTCGAGCGCATCAAAAAACCTTTAAAAAGTGACATGAATGTTGTGCCATACATTGAT
GTGATGCTGGTATTACTGGT

Product: group A colicins tolerance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MATPIQSSLHISDLILQASPVVQAVMLILLLASIYSWYLIAKLHLSYKKSAQQDEHFQKMFWSGAELNTLYNNAQLNSKR
TGLEDIFYHGLGEFFKLKKRQATSTQTIEGTERILRVGLSRDQSQLEQGLGTLASIGSVAPYVGLFGTVWGIMNAFIGLA
AVDQVTLATVAPGIAEALIATAIGLFAAIPAVLAFNHFTSKGEAIYSDRALFAEEMVALLQRQSVGSTQEDA

Sequences:

>Translated_232_residues
MATPIQSSLHISDLILQASPVVQAVMLILLLASIYSWYLIAKLHLSYKKSAQQDEHFQKMFWSGAELNTLYNNAQLNSKR
TGLEDIFYHGLGEFFKLKKRQATSTQTIEGTERILRVGLSRDQSQLEQGLGTLASIGSVAPYVGLFGTVWGIMNAFIGLA
AVDQVTLATVAPGIAEALIATAIGLFAAIPAVLAFNHFTSKGEAIYSDRALFAEEMVALLQRQSVGSTQEDA
>Mature_231_residues
ATPIQSSLHISDLILQASPVVQAVMLILLLASIYSWYLIAKLHLSYKKSAQQDEHFQKMFWSGAELNTLYNNAQLNSKRT
GLEDIFYHGLGEFFKLKKRQATSTQTIEGTERILRVGLSRDQSQLEQGLGTLASIGSVAPYVGLFGTVWGIMNAFIGLAA
VDQVTLATVAPGIAEALIATAIGLFAAIPAVLAFNHFTSKGEAIYSDRALFAEEMVALLQRQSVGSTQEDA

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=229, Percent_Identity=44.9781659388646, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1789381, Length=208, Percent_Identity=36.0576923076923, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25210; Mature: 25079

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPIQSSLHISDLILQASPVVQAVMLILLLASIYSWYLIAKLHLSYKKSAQQDEHFQKM
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
FWSGAELNTLYNNAQLNSKRTGLEDIFYHGLGEFFKLKKRQATSTQTIEGTERILRVGLS
HHCCCHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
RDQSQLEQGLGTLASIGSVAPYVGLFGTVWGIMNAFIGLAAVDQVTLATVAPGIAEALIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAIGLFAAIPAVLAFNHFTSKGEAIYSDRALFAEEMVALLQRQSVGSTQEDA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ATPIQSSLHISDLILQASPVVQAVMLILLLASIYSWYLIAKLHLSYKKSAQQDEHFQKM
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
FWSGAELNTLYNNAQLNSKRTGLEDIFYHGLGEFFKLKKRQATSTQTIEGTERILRVGLS
HHCCCHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
RDQSQLEQGLGTLASIGSVAPYVGLFGTVWGIMNAFIGLAAVDQVTLATVAPGIAEALIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAIGLFAAIPAVLAFNHFTSKGEAIYSDRALFAEEMVALLQRQSVGSTQEDA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]