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The map label for this gene is cbl [H]

Identifier: 50085670

GI number: 50085670

Start: 2554007

End: 2554930

Strand: Direct

Name: cbl [H]

Synonym: ACIAD2597

Alternate gene names: 50085670

Gene position: 2554007-2554930 (Clockwise)

Preceding gene: 50085669

Following gene: 50085672

Centisome position: 70.97

GC content: 40.58

Gene sequence:

>924_bases
ATGAATTTTCAACAGCTTAGAATTATTCGGGAAACCGTTCGTCAAAACTTTAATCTGACCGAGGCATCTGCTGCGTTATA
TACGTCTCAGTCTGGGGTAAGTAAACACATTAAAGACTTAGAAGATGAACTAGGTGTACAACTGTTCATCAGAAAAGGCA
AACGCTTACTTGGCCTGACCGAACCTGGACAATCCTTGCTGGGGATTGTAGAGCGTATGCTGGTCGATGCAGAAAATATC
AAACGTTTGGCTGATGATTTTAATAAAGTCGATGAAGGTACTCTTACTATCGCCACTACACATACTCAAGCACGCTATGT
CCTTCCGCCTATTGTCAATCAGTTTAAAAAACTGTTTCCCAAAGTTCATCTAATTTTGCAGCAGGCCAGCCCTACCGAAA
TTTCAGAGATGCTGTTACAGGGGGAAGCAGATATTGGAATTGCAACTGAATCTCTTACTACAGAAGAAAATTTGGCAAGC
ATTCCTTATTATCAGTGGGAACACAGTATTATTACCCCACAAAATCATCCCCTTACCCAAGTGCCTGAAATTACCTTAGA
AACATTGGCGCATTATCCAATCATTACCTATCATGGCGGCTTTACAGGTCGTTCTAAAATTGACAAAGCATTTGATGATG
CAGGCATTGATGTTGATATTGTCATGTCTGCACTTGATGCGGATGTGATCAAAACCTATGTAGAGCTAAATATGGGGGTG
GGTATTGTCAATGATGTGGCTTACGACAAAGAACGGGATTATCGTCTCAATCAAATCAAGACAGGTATCTTTGGTCTAAA
TACCACTTGGATTGCTGTGCGCAAAGGACATCTTTTGCGTGGATATGGCTATGAGTTCATTTCTCTATGCTCACCTGAAG
CCAATATTAAAGAGCTTAAAAAAATTGCCTACCCTGAAGATTAA

Upstream 100 bases:

>100_bases
TGGATTAGTGTTTCACAGCTTCATCTTTTTGCAGATCATGTTGCCTAAATAAATTTGATGGGGTAATGAACCCCATCCTC
GTTGAGAGGATAAAGAGAAT

Downstream 100 bases:

>100_bases
GCAAAACAATAAGCCATAAAAAACGGGATTGAAATCCCGTTTTTTTATTTGGATGGATCTTACCAGTAGAAGTTTACACC
TACTTTACCTACTGGTAACC

Product: CysB family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNFQQLRIIRETVRQNFNLTEASAALYTSQSGVSKHIKDLEDELGVQLFIRKGKRLLGLTEPGQSLLGIVERMLVDAENI
KRLADDFNKVDEGTLTIATTHTQARYVLPPIVNQFKKLFPKVHLILQQASPTEISEMLLQGEADIGIATESLTTEENLAS
IPYYQWEHSIITPQNHPLTQVPEITLETLAHYPIITYHGGFTGRSKIDKAFDDAGIDVDIVMSALDADVIKTYVELNMGV
GIVNDVAYDKERDYRLNQIKTGIFGLNTTWIAVRKGHLLRGYGYEFISLCSPEANIKELKKIAYPED

Sequences:

>Translated_307_residues
MNFQQLRIIRETVRQNFNLTEASAALYTSQSGVSKHIKDLEDELGVQLFIRKGKRLLGLTEPGQSLLGIVERMLVDAENI
KRLADDFNKVDEGTLTIATTHTQARYVLPPIVNQFKKLFPKVHLILQQASPTEISEMLLQGEADIGIATESLTTEENLAS
IPYYQWEHSIITPQNHPLTQVPEITLETLAHYPIITYHGGFTGRSKIDKAFDDAGIDVDIVMSALDADVIKTYVELNMGV
GIVNDVAYDKERDYRLNQIKTGIFGLNTTWIAVRKGHLLRGYGYEFISLCSPEANIKELKKIAYPED
>Mature_307_residues
MNFQQLRIIRETVRQNFNLTEASAALYTSQSGVSKHIKDLEDELGVQLFIRKGKRLLGLTEPGQSLLGIVERMLVDAENI
KRLADDFNKVDEGTLTIATTHTQARYVLPPIVNQFKKLFPKVHLILQQASPTEISEMLLQGEADIGIATESLTTEENLAS
IPYYQWEHSIITPQNHPLTQVPEITLETLAHYPIITYHGGFTGRSKIDKAFDDAGIDVDIVMSALDADVIKTYVELNMGV
GIVNDVAYDKERDYRLNQIKTGIFGLNTTWIAVRKGHLLRGYGYEFISLCSPEANIKELKKIAYPED

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=302, Percent_Identity=50.9933774834437, Blast_Score=337, Evalue=9e-94,
Organism=Escherichia coli, GI1787530, Length=294, Percent_Identity=44.8979591836735, Blast_Score=261, Evalue=4e-71,
Organism=Escherichia coli, GI157672245, Length=225, Percent_Identity=31.1111111111111, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788481, Length=299, Percent_Identity=27.7591973244147, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI2367136, Length=234, Percent_Identity=22.6495726495727, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790399, Length=253, Percent_Identity=24.1106719367589, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788887, Length=245, Percent_Identity=28.1632653061224, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082132, Length=137, Percent_Identity=32.8467153284672, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790262, Length=199, Percent_Identity=28.1407035175879, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI145693105, Length=230, Percent_Identity=22.1739130434783, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789204, Length=230, Percent_Identity=25.6521739130435, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787879, Length=196, Percent_Identity=25, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34534; Mature: 34534

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQQLRIIRETVRQNFNLTEASAALYTSQSGVSKHIKDLEDELGVQLFIRKGKRLLGLT
CCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHCCCEEEECC
EPGQSLLGIVERMLVDAENIKRLADDFNKVDEGTLTIATTHTQARYVLPPIVNQFKKLFP
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEECCCCEEECCHHHHHHHHHHH
KVHLILQQASPTEISEMLLQGEADIGIATESLTTEENLASIPYYQWEHSIITPQNHPLTQ
HHHHHHHCCCCHHHHHHHHCCCCCCEEEECCCCCHHHHHCCCCEECCCCEECCCCCCCCC
VPEITLETLAHYPIITYHGGFTGRSKIDKAFDDAGIDVDIVMSALDADVIKTYVELNMGV
CCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
GIVNDVAYDKERDYRLNQIKTGIFGLNTTWIAVRKGHLLRGYGYEFISLCSPEANIKELK
CCHHHHHCCCCCCCCHHHHHHCEECCCCEEEEEECCCEEECCCHHHHHHCCCCCCHHHHH
KIAYPED
HHCCCCC
>Mature Secondary Structure
MNFQQLRIIRETVRQNFNLTEASAALYTSQSGVSKHIKDLEDELGVQLFIRKGKRLLGLT
CCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHCCCEEEECC
EPGQSLLGIVERMLVDAENIKRLADDFNKVDEGTLTIATTHTQARYVLPPIVNQFKKLFP
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEECCCCEEECCHHHHHHHHHHH
KVHLILQQASPTEISEMLLQGEADIGIATESLTTEENLASIPYYQWEHSIITPQNHPLTQ
HHHHHHHCCCCHHHHHHHHCCCCCCEEEECCCCCHHHHHCCCCEECCCCEECCCCCCCCC
VPEITLETLAHYPIITYHGGFTGRSKIDKAFDDAGIDVDIVMSALDADVIKTYVELNMGV
CCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
GIVNDVAYDKERDYRLNQIKTGIFGLNTTWIAVRKGHLLRGYGYEFISLCSPEANIKELK
CCHHHHHCCCCCCCCHHHHHHCEECCCCEEEEEECCCEEECCCHHHHHHCCCCCCHHHHH
KIAYPED
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]