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The map label for this gene is fabG [C]

Identifier: 50085645

GI number: 50085645

Start: 2529407

End: 2530099

Strand: Reverse

Name: fabG [C]

Synonym: ACIAD2570

Alternate gene names: 50085645

Gene position: 2530099-2529407 (Counterclockwise)

Preceding gene: 50085648

Following gene: 50085644

Centisome position: 70.31

GC content: 40.84

Gene sequence:

>693_bases
ATGAGCATTGTTATTGCAGGTGCATCAATAGGAATAGGACAAGCGCTTTATCAGCAATTGAAACGCGAGTCTTTAGATGC
CGTTTACACAATTAGCCGTCGGAATACAGGAAGCTCGAATTTACAGGCGGATTTGTCTAATCCTGCTGATATCGCGCGTG
TACGAGAATTTTTACAGGAGATTCAACCTTCACAGGTTTTTTGTTGTGCTGGACAACTACATGATCAAGATCATATGCCA
GAGAAGCGTTTAAGCCAGATAAATGATGAGTGGATATTCCAGTCTTTGAGGGCAAATCTTTTAAGTCATATTCACTTGGC
TCAGGCGCTTGATCCAATCTTGACCAGAAAGCATGCTTTAAAATGGATATCGCTTTCTGCAAAAGTTGGAAGTCTTGATG
ATAATGCCTTGGGTGGTTGGTACAGTTATCGAATGAGTAAAGCTGCGTTGAATATGTTTATTAAAAACTTGAGCATTGAG
TGGGCGAGAAAATCATCTGATATTCTGGTGGCAAGTGTACATCCTGGTACCACGGATTCTGAGTTGTCTAAACCTTTTCA
GTCTCATATTGTGTCTGATCGGCTTTACACGCCTCAGCAAACGGCAATACGTTTGATTTCGATTATGCAACGTTTATCTT
CAGCACAGCATGGTAAATTACTACATTGGGATGGCAGTGTTATTGCATATTGA

Upstream 100 bases:

>100_bases
AATAGATGAGAATTCAGCCATTTTGATGAGTGACATAAATTTCACATCGATTCATCTAAAATGTACCCAAAATTTATGAA
TACAAGAACAAGAGAGATTT

Downstream 100 bases:

>100_bases
ATGCGATGGCTAAGCCTTGAAAAATCAGAATTTGACCAGATTAATGTTATAAATCCAATTTAATTTTTTAATCATAGAGA
GTGCGTGTGAACGACAACCA

Product: cell-cell signaling protein, C-factor (CsgA)

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: C Factor Cell-Cell Signaling Protein; Oxidoreductase Short Chain Dehydrogenase/Reductase Family; Short Chain Dehydrogenase/Reductase Family Oxidoreductase; C Factor; Short Chain Dehydrogenase; Cell-Cell Signaling Protein C-Factor; CsgA C-Factor Signaling Protein; CsgA Rossman Fold Oxidoreductase; Short-Chain Dehydrogenase/Reductase Superfamily Protein; Dehydrogenase; Cell-Cell Signaling Protein CsgA; SDR Family Dehydrogenase/Reductase; Glucose/Ribitol Dehydrogenase; 2-Methylthioadenine Synthetase; NAD Dependent Epimerase/Dehydratase Family; Oxidoreductase Short-Chain Dehydrogenase/Reductase Family; C-Factor; C Factor Cell Signaling Protein; Short-Chain Dehydrogenase/Reductase Family Protein; Short-Chain Dehydrogenase/Oxidoreductase

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSIVIAGASIGIGQALYQQLKRESLDAVYTISRRNTGSSNLQADLSNPADIARVREFLQEIQPSQVFCCAGQLHDQDHMP
EKRLSQINDEWIFQSLRANLLSHIHLAQALDPILTRKHALKWISLSAKVGSLDDNALGGWYSYRMSKAALNMFIKNLSIE
WARKSSDILVASVHPGTTDSELSKPFQSHIVSDRLYTPQQTAIRLISIMQRLSSAQHGKLLHWDGSVIAY

Sequences:

>Translated_230_residues
MSIVIAGASIGIGQALYQQLKRESLDAVYTISRRNTGSSNLQADLSNPADIARVREFLQEIQPSQVFCCAGQLHDQDHMP
EKRLSQINDEWIFQSLRANLLSHIHLAQALDPILTRKHALKWISLSAKVGSLDDNALGGWYSYRMSKAALNMFIKNLSIE
WARKSSDILVASVHPGTTDSELSKPFQSHIVSDRLYTPQQTAIRLISIMQRLSSAQHGKLLHWDGSVIAY
>Mature_229_residues
SIVIAGASIGIGQALYQQLKRESLDAVYTISRRNTGSSNLQADLSNPADIARVREFLQEIQPSQVFCCAGQLHDQDHMPE
KRLSQINDEWIFQSLRANLLSHIHLAQALDPILTRKHALKWISLSAKVGSLDDNALGGWYSYRMSKAALNMFIKNLSIEW
ARKSSDILVASVHPGTTDSELSKPFQSHIVSDRLYTPQQTAIRLISIMQRLSSAQHGKLLHWDGSVIAY

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 25721; Mature: 25589

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVIAGASIGIGQALYQQLKRESLDAVYTISRRNTGSSNLQADLSNPADIARVREFLQE
CEEEEECCCCCHHHHHHHHHHHHCHHHEEEEECCCCCCCCCEECCCCCHHHHHHHHHHHH
IQPSQVFCCAGQLHDQDHMPEKRLSQINDEWIFQSLRANLLSHIHLAQALDPILTRKHAL
CCCCCEEEECCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KWISLSAKVGSLDDNALGGWYSYRMSKAALNMFIKNLSIEWARKSSDILVASVHPGTTDS
HHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEEECCCCCHH
ELSKPFQSHIVSDRLYTPQQTAIRLISIMQRLSSAQHGKLLHWDGSVIAY
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCEECC
>Mature Secondary Structure 
SIVIAGASIGIGQALYQQLKRESLDAVYTISRRNTGSSNLQADLSNPADIARVREFLQE
EEEEECCCCCHHHHHHHHHHHHCHHHEEEEECCCCCCCCCEECCCCCHHHHHHHHHHHH
IQPSQVFCCAGQLHDQDHMPEKRLSQINDEWIFQSLRANLLSHIHLAQALDPILTRKHAL
CCCCCEEEECCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KWISLSAKVGSLDDNALGGWYSYRMSKAALNMFIKNLSIEWARKSSDILVASVHPGTTDS
HHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEEECCCCCHH
ELSKPFQSHIVSDRLYTPQQTAIRLISIMQRLSSAQHGKLLHWDGSVIAY
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA