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The map label for this gene is ygcS [H]

Identifier: 50085612

GI number: 50085612

Start: 2492005

End: 2493486

Strand: Reverse

Name: ygcS [H]

Synonym: ACIAD2535

Alternate gene names: 50085612

Gene position: 2493486-2492005 (Counterclockwise)

Preceding gene: 50085613

Following gene: 50085609

Centisome position: 69.29

GC content: 39.61

Gene sequence:

>1482_bases
GTGTTTAAAATGAGTCAAATCAATTCGATTGATGCCAATCGATATGAAATTAAAAGTTCAGCCGATGTTTCAAGATTGGT
CTCAAAATTTGCTGGACAGGGGAAAAGTAATAAAGTGATTTGGTTGGCATTGATTGGGGTATTTATCGATGCATATGATC
TTACCACCTTATCTTTTGGTATAGATCAAGTGGTACAAGAGTTTTCACTGACTCCTGTTATGACTGGTGTCGTTGCCTCT
GCCATTATCTGCGGAACCATTGTGGGTAATCTTGTTGGTGGCTGGCTAACCGACAAAATCGGACGCTATCGAGTCTTTAT
GGCCGATATGGTGCTGTTTGTCATTGCGGCTATTGTTGCAGGTTTTGCACCCAATGTATGGGTTTTGATTATTGCACGAT
TTATTATGGGAATTAGTGTTGGAATAGATTTACCTGTTGCCATGTCTTATCTTTCAGAGTTCTCAAAGTTTAGTGGTAAA
AGTAACAAGGCTGCACGTTTAGCGGCATGGTGCCCAATGTGGTATGCAGCTTCTTCGGTATGTTTTGGAATTGTCTTGGC
ATTATATTTTTTATTACCACCCGAACATATCAATTGGTTATGGCGTGCTTCTCTAATTTTTGGTGCTGTTCCTGCTTTGT
TTATTATTTTTATTCGAAGTAAATACTTGACTGAATCTCCTATTTGGTTAGCCAATCAAGGCAATTTGGCAGGAGCTGCC
AAAATTTTACGTGAATCGTATGATATCAATGCTTTTGCAAGCCCTGAACCTGTAATAAAAAAAGCAGCAATTAAACCACC
TAAACTCAGTTTCAAGGTGCTATTCAATAAGACCTATTTGCCGAGAACTATTGTTTCTTTAGTGATTCATGTTTCGGTCG
CTTTTCAATATACAACGATTGCCTTCTTTCTACCGTCAATCTTAATGCGCTTTTTTCATACAGATGTGTTAACTACCATT
ACAACAACGTTAGGATTAAACCTGCTTTTTGCATTTACTGGTGGTTTACTCGGTATATATGTTGCGAGCCGCTTGGCATC
TAGACATATTTTACTTGTGGGATTTTTCTTGCAATTCATCGCTCTAATTGTTTTATCGTACATTGGAGAGCCTCAGAATC
CTTATCTGGTATATACCGCGATTATCATGTTGGGATTATGGTTGTTCGCAGAAGGTTTTGGGCCTGGCGCACAAATGATG
GTTTATCCAACTATGGCATATCCCGCCGAAATCCGTGGAATTGGCGTTGGTTTTAATCGTGCTGTAACTGGCGTGGCACA
GGCCAGTGCGATGTTTTTACTTCCTATCTGGATGGCACGTTATCAAACCGATGTGTTTTTAATCATCTCTATTTTTGCTG
TTATTCCGCTGGTTGTGATTGGACTGCTGATTAAGTATGAACCTACTGCACAGGATATTGATGCGAAAGATCCTGAACAT
GATAAAAAGTCAGGTTTGGATGCTGTAGCTGTGGCAGATTAA

Upstream 100 bases:

>100_bases
AGAAAATGATTAAATCATAAAAATGAATTTATTATAAATTTTTAATTATTTTATTTATTTATATCTCAACCTATATATTA
AGTTATACGAATAATGGGTT

Downstream 100 bases:

>100_bases
TCATTAAAACCTGCAAAAAATAAGAACCTAAATTTAGGTTCTTATTTTTGATGGATCTGGATAAATATAACCGTCAATTA
TCACATAGCGTATTTAATTG

Product: MFS family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MFKMSQINSIDANRYEIKSSADVSRLVSKFAGQGKSNKVIWLALIGVFIDAYDLTTLSFGIDQVVQEFSLTPVMTGVVAS
AIICGTIVGNLVGGWLTDKIGRYRVFMADMVLFVIAAIVAGFAPNVWVLIIARFIMGISVGIDLPVAMSYLSEFSKFSGK
SNKAARLAAWCPMWYAASSVCFGIVLALYFLLPPEHINWLWRASLIFGAVPALFIIFIRSKYLTESPIWLANQGNLAGAA
KILRESYDINAFASPEPVIKKAAIKPPKLSFKVLFNKTYLPRTIVSLVIHVSVAFQYTTIAFFLPSILMRFFHTDVLTTI
TTTLGLNLLFAFTGGLLGIYVASRLASRHILLVGFFLQFIALIVLSYIGEPQNPYLVYTAIIMLGLWLFAEGFGPGAQMM
VYPTMAYPAEIRGIGVGFNRAVTGVAQASAMFLLPIWMARYQTDVFLIISIFAVIPLVVIGLLIKYEPTAQDIDAKDPEH
DKKSGLDAVAVAD

Sequences:

>Translated_493_residues
MFKMSQINSIDANRYEIKSSADVSRLVSKFAGQGKSNKVIWLALIGVFIDAYDLTTLSFGIDQVVQEFSLTPVMTGVVAS
AIICGTIVGNLVGGWLTDKIGRYRVFMADMVLFVIAAIVAGFAPNVWVLIIARFIMGISVGIDLPVAMSYLSEFSKFSGK
SNKAARLAAWCPMWYAASSVCFGIVLALYFLLPPEHINWLWRASLIFGAVPALFIIFIRSKYLTESPIWLANQGNLAGAA
KILRESYDINAFASPEPVIKKAAIKPPKLSFKVLFNKTYLPRTIVSLVIHVSVAFQYTTIAFFLPSILMRFFHTDVLTTI
TTTLGLNLLFAFTGGLLGIYVASRLASRHILLVGFFLQFIALIVLSYIGEPQNPYLVYTAIIMLGLWLFAEGFGPGAQMM
VYPTMAYPAEIRGIGVGFNRAVTGVAQASAMFLLPIWMARYQTDVFLIISIFAVIPLVVIGLLIKYEPTAQDIDAKDPEH
DKKSGLDAVAVAD
>Mature_493_residues
MFKMSQINSIDANRYEIKSSADVSRLVSKFAGQGKSNKVIWLALIGVFIDAYDLTTLSFGIDQVVQEFSLTPVMTGVVAS
AIICGTIVGNLVGGWLTDKIGRYRVFMADMVLFVIAAIVAGFAPNVWVLIIARFIMGISVGIDLPVAMSYLSEFSKFSGK
SNKAARLAAWCPMWYAASSVCFGIVLALYFLLPPEHINWLWRASLIFGAVPALFIIFIRSKYLTESPIWLANQGNLAGAA
KILRESYDINAFASPEPVIKKAAIKPPKLSFKVLFNKTYLPRTIVSLVIHVSVAFQYTTIAFFLPSILMRFFHTDVLTTI
TTTLGLNLLFAFTGGLLGIYVASRLASRHILLVGFFLQFIALIVLSYIGEPQNPYLVYTAIIMLGLWLFAEGFGPGAQMM
VYPTMAYPAEIRGIGVGFNRAVTGVAQASAMFLLPIWMARYQTDVFLIISIFAVIPLVVIGLLIKYEPTAQDIDAKDPEH
DKKSGLDAVAVAD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI7662270, Length=322, Percent_Identity=22.6708074534161, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI262399383, Length=267, Percent_Identity=24.3445692883895, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87082159, Length=393, Percent_Identity=29.0076335877863, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786229, Length=405, Percent_Identity=24.4444444444444, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788068, Length=242, Percent_Identity=30.5785123966942, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789207, Length=321, Percent_Identity=28.6604361370716, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788074, Length=375, Percent_Identity=26.1333333333333, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789312, Length=410, Percent_Identity=25.609756097561, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082404, Length=395, Percent_Identity=21.5189873417722, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI87082231, Length=219, Percent_Identity=27.8538812785388, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320705, Length=382, Percent_Identity=23.5602094240838, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 54119; Mature: 54119

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCEEEECC
>Mature Secondary Structure
MFKMSQINSIDANRYEIKSSADVSRLVSKFAGQGKSNKVIWLALIGVFIDAYDLTTLSFG
CCCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IDQVVQEFSLTPVMTGVVASAIICGTIVGNLVGGWLTDKIGRYRVFMADMVLFVIAAIVA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFAPNVWVLIIARFIMGISVGIDLPVAMSYLSEFSKFSGKSNKAARLAAWCPMWYAASSV
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
CFGIVLALYFLLPPEHINWLWRASLIFGAVPALFIIFIRSKYLTESPIWLANQGNLAGAA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHH
KILRESYDINAFASPEPVIKKAAIKPPKLSFKVLFNKTYLPRTIVSLVIHVSVAFQYTTI
HHHHHHCCCCCCCCCCHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
AFFLPSILMRFFHTDVLTTITTTLGLNLLFAFTGGLLGIYVASRLASRHILLVGFFLQFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIVLSYIGEPQNPYLVYTAIIMLGLWLFAEGFGPGAQMMVYPTMAYPAEIRGIGVGFNR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHEEECCCHHH
AVTGVAQASAMFLLPIWMARYQTDVFLIISIFAVIPLVVIGLLIKYEPTAQDIDAKDPEH
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
DKKSGLDAVAVAD
HHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]