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The map label for this gene is prmA

Identifier: 50085527

GI number: 50085527

Start: 2408200

End: 2409111

Strand: Direct

Name: prmA

Synonym: ACIAD2443

Alternate gene names: 50085527

Gene position: 2408200-2409111 (Clockwise)

Preceding gene: 50085526

Following gene: 50085528

Centisome position: 66.92

GC content: 40.9

Gene sequence:

>912_bases
GTGAAGTGGTTACAAATACACATTACTGTCGATCAAGATCAAGTTGATTTTACCGAAACTTTACTCATGTCCCTAGGTGC
AGTAAGTGTGACTCTAGATGATGCCGAGGATCAGGCATTGCTTGAACCCCTTCCTGGAGAGACCCCTCTCTGGAATAAAG
TGATTGTTACTGGGATCTATCAAGAAGATGATAATGATCCAATTGATGTTGAAAAACTAAAAGCCTTTTTACAAGCACAA
CTTCCAAATATTCCCATGCGCCATGAACAATTGGAAGACCAAGTCTGGGAACGTGCTTGGATGGATTATTATGATCCGAT
TCAAATTGGTGAAAAATTTTGGATTGTTCCTGAATGGCTGGAGCCGCCTGAAGCAGATGCAACCAATATCAAGCTTGATC
CAGGGCTTGCTTTTGGAACAGGAAATCATGCCAGCACCTTTTTATGCTTGCAATGGTTGGGCAAGACAGACTTAAAAGAT
AAAGTCGTCATTGATTATGGCTGTGGTTCTGGGATTTTAGCCGTTGCAGCATTACTTTTGGGTGCCCAAAAAGTATATGC
GACAGATATCGACCCTCAAGCGGTACTGGCAACTAAGCAAAATGCCGAATTAAACAATGTGTTGGAACGACTTTATGTCG
GCTTACCTGAAGAATTTAATACAGAGTTCAAGGCTTCCGGTTCACAAGCAGATGTACTTGTTGCCAATATTCTTGCTAGC
CCACTCATGATGCTGGCACCAGAATTTGCGACATTAATTAAACCTCAAGGTGAGTTTGCACTGGCGGGCATCATTGAAGA
ACAAGTTGATGATGTTTCAGAAGTTTATCAACAATATTTTGATATTTTAAATATTGAAAAACGTGAAGAAAACTGGTGTC
GTATTTCAGGAAAGCGTCATTCTCAGGCTTAA

Upstream 100 bases:

>100_bases
TCAGTTATTCTGAGCCGTTTTCTTTTAGGTATATCTCCTTTATTTGCTGATCATCAGCTACAATACCCGACAATGTTGAA
ATGAAATTTAAGGTATTCCC

Downstream 100 bases:

>100_bases
ATAAGGCTAGTTTGTAAATGAGTGAAAAGCATACCCGTTGCCCTCGATGCGAAACGATCTATAAAGTTTCGCAAAAACAG
CTCACGCTGTCTCAAGGCAT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKWLQIHITVDQDQVDFTETLLMSLGAVSVTLDDAEDQALLEPLPGETPLWNKVIVTGIYQEDDNDPIDVEKLKAFLQAQ
LPNIPMRHEQLEDQVWERAWMDYYDPIQIGEKFWIVPEWLEPPEADATNIKLDPGLAFGTGNHASTFLCLQWLGKTDLKD
KVVIDYGCGSGILAVAALLLGAQKVYATDIDPQAVLATKQNAELNNVLERLYVGLPEEFNTEFKASGSQADVLVANILAS
PLMMLAPEFATLIKPQGEFALAGIIEEQVDDVSEVYQQYFDILNIEKREENWCRISGKRHSQA

Sequences:

>Translated_303_residues
MKWLQIHITVDQDQVDFTETLLMSLGAVSVTLDDAEDQALLEPLPGETPLWNKVIVTGIYQEDDNDPIDVEKLKAFLQAQ
LPNIPMRHEQLEDQVWERAWMDYYDPIQIGEKFWIVPEWLEPPEADATNIKLDPGLAFGTGNHASTFLCLQWLGKTDLKD
KVVIDYGCGSGILAVAALLLGAQKVYATDIDPQAVLATKQNAELNNVLERLYVGLPEEFNTEFKASGSQADVLVANILAS
PLMMLAPEFATLIKPQGEFALAGIIEEQVDDVSEVYQQYFDILNIEKREENWCRISGKRHSQA
>Mature_303_residues
MKWLQIHITVDQDQVDFTETLLMSLGAVSVTLDDAEDQALLEPLPGETPLWNKVIVTGIYQEDDNDPIDVEKLKAFLQAQ
LPNIPMRHEQLEDQVWERAWMDYYDPIQIGEKFWIVPEWLEPPEADATNIKLDPGLAFGTGNHASTFLCLQWLGKTDLKD
KVVIDYGCGSGILAVAALLLGAQKVYATDIDPQAVLATKQNAELNNVLERLYVGLPEEFNTEFKASGSQADVLVANILAS
PLMMLAPEFATLIKPQGEFALAGIIEEQVDDVSEVYQQYFDILNIEKREENWCRISGKRHSQA

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=302, Percent_Identity=45.364238410596, Blast_Score=232, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_ACIAD (Q6F9P9)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047037.1
- ProteinModelPortal:   Q6F9P9
- STRING:   Q6F9P9
- GeneID:   2880044
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD2443
- NMPDR:   fig|62977.3.peg.2046
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   EREEWCR
- PhylomeDB:   Q6F9P9
- ProtClustDB:   PRK00517
- BioCyc:   ASP62977:ACIAD2443-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33989; Mature: 33989

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWLQIHITVDQDQVDFTETLLMSLGAVSVTLDDAEDQALLEPLPGETPLWNKVIVTGIY
CCEEEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCHHHHCCCCCCCCCCCCEEEEEEE
QEDDNDPIDVEKLKAFLQAQLPNIPMRHEQLEDQVWERAWMDYYDPIQIGEKFWIVPEWL
ECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCEEEEECCCC
EPPEADATNIKLDPGLAFGTGNHASTFLCLQWLGKTDLKDKVVIDYGCGSGILAVAALLL
CCCCCCCCEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHH
GAQKVYATDIDPQAVLATKQNAELNNVLERLYVGLPEEFNTEFKASGSQADVLVANILAS
CCHHHEECCCCCHHEEEECCCCHHHHHHHHHHCCCCHHHCCCHHCCCCCHHHHHHHHHHH
PLMMLAPEFATLIKPQGEFALAGIIEEQVDDVSEVYQQYFDILNIEKREENWCRISGKRH
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCC
SQA
CCC
>Mature Secondary Structure
MKWLQIHITVDQDQVDFTETLLMSLGAVSVTLDDAEDQALLEPLPGETPLWNKVIVTGIY
CCEEEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCHHHHCCCCCCCCCCCCEEEEEEE
QEDDNDPIDVEKLKAFLQAQLPNIPMRHEQLEDQVWERAWMDYYDPIQIGEKFWIVPEWL
ECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCEEEEECCCC
EPPEADATNIKLDPGLAFGTGNHASTFLCLQWLGKTDLKDKVVIDYGCGSGILAVAALLL
CCCCCCCCEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHH
GAQKVYATDIDPQAVLATKQNAELNNVLERLYVGLPEEFNTEFKASGSQADVLVANILAS
CCHHHEECCCCCHHEEEECCCCHHHHHHHHHHCCCCHHHCCCHHCCCCCHHHHHHHHHHH
PLMMLAPEFATLIKPQGEFALAGIIEEQVDDVSEVYQQYFDILNIEKREENWCRISGKRH
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCC
SQA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA